Medicine, Nephrology, Molecular Genetics

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Volunteer Basis, Potential for UROP Funding, Potential for Work-Study Funding, Potential for Academic Credit

Overview

Chronic kidney disease (CKD) is one of the top 10 leading causes of death globally. CKD affects an estimated 13% of the population (~37 million) in the US and over 850 million people worldwide and costs the US at least $50 billion each year. However, few kidney-specific medical therapies are currently available for CKD, posing a significant unmet medical need. The ultimate goals of research programs in Dr. Lu’s laboratory are to understand the pathobiology of kidney diseases and discover and develop novel therapeutics for patients with CKD.

The current research opportunities of Dr. Lu’s laboratory are in the following four scientific areas: 1) Molecular genetics of the kidney and urinary tract development and congenital anomalies of the kidney and urinary tract (CAKUT). 2) Biological function and disease mechanism of kidney and urinary tract congenital disability genes and their roles after birth in CKD. 3) SLIT/ROBO and ZEB signaling in kidney and urinary tract development and CKD. 4) Discovery and development of novel drug targets and therapeutics for patients with CKD. The research programs in Dr. Lu’s Lab can be found on BU’s website: https://profiles.bu.edu/Weining.Lu.

We welcome motivated and engaged undergraduate researchers participating in basic, translational, and clinical research projects in the LU lab. The research projects are suitable for students who make a longitudinal long–term commitment to biomedical research and future career in medicine and biological sciences. Previous students in Dr. Lu’s lab have gone to medical school, graduate school, dental school, academic medical center, and industry. For inquiries regarding UROP research opportunities in the LU lab, please get in touch with Dr. Lu at wlu@bu.edu.

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