Immunology / Opthalmology

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Volunteer Basis, Potential for UROP Funding, Potential for Academic Credit

Overview

Within the healthy eye are mechanisms to control and manipulate immunity necessary to preserve vision. Several specific neuropeptides within the eye regulate different immune cells and different immune cell functions. Collectively they suppress inflammation and promote immune cell-mediated anti-inflammatory activity and immune tolerance. Understanding how these neuropeptides alter immunity and work together to suppress inflammation profoundly impacts finding ways to reestablish health in eyes following infection, graft rejection, autoimmune disease, and trauma. In addition, advances in understanding how these neuropeptides regulate immunity within the eye lead to using these same neuropeptides to regulate immunity in other tissues. Our experimental approach uses molecular biology, biochemistry, histology, immunohistochemistry, flow cytometry, gene expression, cultured immune cells, and immune model techniques. There is a separate research opportunity for each student linked to the general study of vision science and immunobiology. These opportunities, based on accomplishment, could contribute to conference abstracts and publications. We are looking for sophomore and junior students interested in a multi-year research experience in our lab.

Contact Dr. Taylor at awtaylor@bu.edu with your CV and your sophomore or junior class schedule.

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