Glycoproteomics, Mass Spectrometry

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Volunteer Basis, Independent Funding Available, Potential for UROP Funding, Potential for Academic Credit

Overview

Protein glycosylation, the study of complex sugars (glycans) to polypeptides, is an important post-translational modification that play diverse roles in intercellular processes. Viral proteins, for example in SARS-CoV-2 and Influenza viruses, are heavily glycosylated that help them in host cell invasion, budding and infection. Quantifying glycosylation changes is vital for mechanistic understanding of human health and disease processes. We are working on characterizing the viral glycopeptides and understanding their roles in viral infection using a versatile mass spectrometry approach.

Boston University undergraduates are welcome to apply for short-term research internship in the lab. This is an excellent opportunity for students who are curious and motivated and want to gain hands-on experience in the lab. Basic molecular and cell biology techniques, hands-on training of mass spectrometer and handling of relevant software and bio-informatics tools will be taught to incoming candidates. This will form valuable early-on training to students who want to pursue a long-term research career and we will provide committed guidance (training, recommendation letters) that will help you in your next career stages.

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