{"id":91849,"date":"2016-10-16T05:00:39","date_gmt":"2016-10-16T09:00:39","guid":{"rendered":"https:\/\/www.bu.edu\/sph\/?p=91849"},"modified":"2021-02-16T16:23:45","modified_gmt":"2021-02-16T21:23:45","slug":"on-knowledge-and-values","status":"publish","type":"bu-article","link":"https:\/\/www.bu.edu\/sph\/news\/articles\/2016\/on-knowledge-and-values\/","title":{"rendered":"On Knowledge and Values"},"content":{"rendered":"\n<div class=\"wp-prepress-component-metabar sphnews-prepress-layout-metabar\">\n\t<div class=\"wp-prepress-component-metabar-wrapper\">\n\t\t\t\t\t<div class=\"wp-prepress-component-metabar-date\">October 16, 2016<\/div>\n\t\t\n\t\t\t\t<div class=\"wp-prepress-component-metabar-credits\">\n\t\t\t\t\t<\/div>\n\t\t<div class=\"wp-prepress-component-metabar-share js-bu-prepress-share-tools\">\n\t\t\t<span class=\"icon-twitter\"><span>Twitter<\/span><\/span>\n\t\t\t<span class=\"icon-facebook\"><span>Facebook<\/span><\/span>\n\t\t\t<span class=\"icon-action\"><\/span>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<p><strong><img loading=\"lazy\" src=\"\/sph\/files\/2014\/12\/thisweek365-deans-note.png\" alt=\"thisweek365-deans-note\" class=\"alignleft size-full wp-image-59530\" width=\"400\" height=\"241\" \/><\/strong><\/p>\n<p><strong><\/strong>Before I start today\u2019s note, a quick coda to last week\u2019s Dean\u2019s Note about obesity. A new <a href=\"http:\/\/apps.who.int\/iris\/bitstream\/10665\/250131\/1\/9789241511247-eng.pdf?ua=1\" target=\"_blank\" rel=\"noopener noreferrer\">World Health Organization technical report<\/a>\u00a0 endorses soda taxes to reduce the spread of obesity, aligning well, to my mind, with the evidence that ultimately we shall need to change context, <a href=\"https:\/\/www.bu.edu\/sph\/2016\/03\/13\/paternalism-and-public-health\/\">including behavioral incentives<\/a> to drink or not to drink sugary soda, if we are to combat the obesity epidemic.<\/p>\n<p>On to today\u2019s note. There is an <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18287920\" target=\"_blank\" rel=\"noopener noreferrer\">abundance<\/a> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19794192\" target=\"_blank\" rel=\"noopener noreferrer\">of<\/a> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25155527\" target=\"_blank\" rel=\"noopener noreferrer\">writing<\/a> about the translation of science to practice. We have <a href=\"https:\/\/www.bu.edu\/sph\/2015\/01\/11\/some-thoughts-on-the-future-of-academic-public-health\/\">talked<\/a> <a href=\"https:\/\/www.bu.edu\/sph\/2015\/02\/28\/an-agenda-for-an-activist-academic-public-health\/\">frequently<\/a> about the core role of a school of public health in contributing to this translation process. Yet we are often confronted with the seeming immutability of some poor population health conditions. <a href=\"http:\/\/www.webmd.com\/diet\/obesity\/features\/obesity-epidemic-astronomical#1\" target=\"_blank\" rel=\"noopener noreferrer\">Obesity continues to rise<\/a>. <a href=\"https:\/\/www.wired.com\/2016\/10\/america-battling-horrific-opioid-epidemic\/\" target=\"_blank\" rel=\"noopener noreferrer\">The opioid epidemic rages<\/a>. <a href=\"http:\/\/www.bradycampaign.org\/key-gun-violence-statistics\" target=\"_blank\" rel=\"noopener noreferrer\">And tens of thousands of people are killed by guns every year<\/a>. Why? Why is there a gap between science and action? Why does science not always result in clearer action, particularly when we may have data suggesting how we may improve the health of populations?<\/p>\n<p>I have come to feel that the core challenge of the evidence-to-practice gap rests around the intersection of two areas: our knowledge and our values, i.e., what we know and what we hold to be important.\u00a0 And that we need to have both clarity of evidence pointing to effective action and societal buy-In supporting that action in order for us to improve the health of populations. Our knowledge anchors our aspirations in the realm of the possible\u2014what we can appreciably <em>do<\/em> at a given time, informed by what we know. Our values shape the direction we would like to go in as a community, the issues we would like to move forward; indeed, our priorities. While we are certainly able to act, and to succeed, without full knowledge, and while we have sometimes acted with imperfect knowledge when we have felt that the occasion required it, I would argue that public health is best able to point to solutions when we provide data that suggest clarity of action, and contribute to an environment where societal values are welcoming of these data. A Note, then, on striking the knowledge-values balance, to improve the health of populations.<\/p>\n<p>How do we generate knowledge? What does it really mean to \u201cknow\u201d something? A traditional approach to epistemology\u2014the study of knowledge\u2014holds that there are <a href=\"http:\/\/plato.stanford.edu\/entries\/knowledge-analysis\/#BelCon\" target=\"_blank\" rel=\"noopener noreferrer\">three components<\/a> to knowledge: truth, belief, and justification. \u201cTruth\u201d simply means that, for something to be genuine knowledge, it must be true. This was famously expressed by Aristotle, in his <a href=\"http:\/\/www.logicmuseum.com\/wiki\/Truth_(Aristotle)\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Metaphysics<\/em><\/a>: &#8220;To say of something which is that it is not, or to say of something which is not that it is, is false. However, to say of something which is that it is, or of something which is not that it is not, is true.&#8221; The importance of \u201cbelief\u201d is fairly straightforward, as <a href=\"http:\/\/www.philosophybasics.com\/branch_epistemology.html\" target=\"_blank\" rel=\"noopener noreferrer\">it would be contradictory<\/a> to claim to both know something and not believe in it. \u201cJustification\u201d is less clear-cut. <a href=\"http:\/\/plato.stanford.edu\/entries\/plato-theaetetus\/\" target=\"_blank\" rel=\"noopener noreferrer\">In Plato\u2019s <em>Theaetetus<\/em><\/a>, Socrates considers that knowledge might be defined as \u201ctrue belief with an account.\u201d This is to say that knowledge is not merely belief in a true proposition; it is true belief that is supported by some kind of evidence, true belief that has been properly accounted for. This process of justification, of accounting for what we believe to be true, is a key function of our school and our scholarship.\u00a0To say that we \u201cknow\u201d something, within the context of our field, emerges from the work of many, through iterative research, writing, and debate. The scientific method and the rigor of peer review exist to provide a framework for this work of justification. Our tradition of discussion and argument\u2014both among ourselves and through the structure of various fora\u2014allows us to further refine what we know. This process is, by design, neither easy nor quick. Yet for us to call \u201cknowledge\u201d what may have started as an idea, a hunch, means we must engage with each step along the road from supposition, to proof, to, ultimately, consensus around a given issue.<\/p>\n<p>What are values? What do we mean when we say we care about something? Values are what we choose to focus on, in a world of limited time and resources. This choice is both necessary\u2014if we are to get anything done\u2014and deeply revealing. Indeed, the philosopher Jos\u00e9 Ortega y Gasset <a href=\"https:\/\/en.wikiquote.org\/wiki\/Jos\u00e9_Ortega_y_Gasset\" target=\"_blank\" rel=\"noopener noreferrer\">once wrote<\/a>, \u201cTell me to what you pay attention, and I will tell you who you are.\u201d Normative ethics, the branch of ethics that assigns moral value to actions, puts forth three types of ethical theories to inform action: virtue, deontology, and consequentialism. Virtue ethics are concerned with the moral character of the person or people performing an action\u2014i.e. are they good people acting in good faith? This means that, for an action to be ethical, it does not necessarily have to produce positive results, as long as it is performed by virtuous people. Deontology is concerned with the action itself\u2014i.e. is it the right step to take? Is it being performed correctly? Under this system, intrinsically bad actions should be avoided, even if they may lead to positive results. Consequentialism is concerned with outcomes\u2014i.e. what did this action, in the end, actually do? In all of these cases, values are defined by their relationship to what we do, and I have previously argued for a particular role for <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24022890\" target=\"_blank\" rel=\"noopener noreferrer\">consequentialism<\/a> in informing population health science. I argue for this, in part, because I see it as speaking to a fundamental truth about values\u2014they tend to catalyze action. When we genuinely care about something, particularly when it is an injustice in need of correcting or a matter of lives to be saved, it is difficult to remain a spectator, or to limit our activities to the accumulation of knowledge for its own sake. Our values push us to mobilize our knowledge in pursuit of healthier populations, guiding our priorities towards the areas where we can best make a difference.<\/p>\n<p>So, what of the intersection of knowledge and values? To illustrate the intersection, and occasional gulf, between our knowledge and our values, I would like to propose a 2-by-2 grid inspired <a href=\"https:\/\/www.brookings.edu\/book\/pasteurs-quadrant\/\" target=\"_blank\" rel=\"noopener noreferrer\">by Donald Stokes and his Pasteur\u2019s quadrant<\/a>, which I cited <a href=\"https:\/\/www.bu.edu\/sph\/2015\/10\/11\/pasteurs-quadrant-and-population-heal\/\">in a previous note<\/a>.<\/p>\n<figure id=\"attachment_91866\" aria-describedby=\"caption-attachment-91866\" style=\"width: 777px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" src=\"\/sph\/files\/2016\/10\/knowledge.png\" alt=\"Figure 1\" class=\"wp-image-91866 size-full\" width=\"767\" height=\"649\" srcset=\"https:\/\/www.bu.edu\/sph\/files\/2016\/10\/knowledge.png 767w, https:\/\/www.bu.edu\/sph\/files\/2016\/10\/knowledge-636x538.png 636w, https:\/\/www.bu.edu\/sph\/files\/2016\/10\/knowledge-755x639.png 755w\" sizes=\"(max-width: 767px) 100vw, 767px\" \/><figcaption id=\"caption-attachment-91866\" class=\"wp-caption-text\"><strong>Figure 1<\/strong><\/figcaption><\/figure>\n<p>At the top right of the table are issues where we know what to do, and where public consensus, informed by values, is indeed aligned with action. At the bottom left, we encounter cases where the way forward is less clear, where our data are incomplete and our actions not yet bolstered by public opinion. In between, the table holds cases where we may have value-informed consensus on the need for action but little data to inform that action, and, vice versa, where we have our data in hand, but no clear mandate from the public to proceed with our efforts.<\/p>\n<p>Four examples to illustrate this framework. At the confluence of knowledge and values is the worldwide fight against polio. In 2016, polio is on the brink of global eradication due to <a href=\"https:\/\/www.devex.com\/news\/polio-on-the-brink-of-eradication-87156\" target=\"_blank\" rel=\"noopener noreferrer\">a combination<\/a> of good data, well-tested methods, and the values-driven decision of governments and public health professionals to <a href=\"https:\/\/www.bu.edu\/sph\/2016\/02\/07\/the-aspirations-and-strategies-of-public-health\/\">prioritize<\/a> ending this terrible disease. Humanity\u2019s <a href=\"http:\/\/www.historyofvaccines.org\/content\/articles\/history-polio-poliomyelitis\" target=\"_blank\" rel=\"noopener noreferrer\">long history with polio<\/a>, and the epoch-changing <a href=\"http:\/\/www.pbs.org\/wgbh\/aso\/databank\/entries\/dm52sa.html\" target=\"_blank\" rel=\"noopener noreferrer\">development of a vaccine<\/a>, has placed efforts against the disease in the strongest possible position for a public health intervention. Governments and NGOs have mobilized resources in order to wipe out polio, and the aims of the scientific community have dovetailed with the will of the public.<\/p>\n<p>On the opposite end of the grid is the example of gun-related injury. Gun violence is a clear threat to public health\u2014<a href=\"https:\/\/www.bostonglobe.com\/opinion\/2016\/08\/09\/getting-smarter-about-guns-one-state-time\/68YctBIyldI9zDOo2lIxeO\/story.html\" target=\"_blank\" rel=\"noopener noreferrer\">in the US there have been more than\u00a08,000 gun deaths and over 17,000 gun-related injuries this year<\/a>. However, our efforts to prevent this ongoing tragedy are not yet supported by sufficient data. Interest group success <a href=\"http:\/\/www.wbur.org\/cognoscenti\/2016\/06\/03\/gun-violence-as-a-public-health-issue-sandro-galea\" target=\"_blank\" rel=\"noopener noreferrer\">at blocking federal funding for gun violence research<\/a> means that <a href=\"http:\/\/www.theatlantic.com\/politics\/archive\/2016\/01\/gun-control-laws-research\/424956\/\" target=\"_blank\" rel=\"noopener noreferrer\">we do not yet know<\/a> all we should about the epidemiology of this problem, hindering our attempts to move the issue forward. The gun lobby has also succeeded, far better than we have, at framing their case <a href=\"https:\/\/www.nraila.org\/second-amendment\/\" target=\"_blank\" rel=\"noopener noreferrer\">as a matter of values<\/a>, whereas our efforts, while certainly motivated by our values, have been hindered by a lack of broad, organized public support.<\/p>\n<p>Closer to the \u201cknowledge\u201d axis, we have the problem of <a href=\"http:\/\/www.cdc.gov\/pwud\/\" target=\"_blank\" rel=\"noopener noreferrer\">injection drug use<\/a>. Injection drug use poses health threats on multiple levels, including the possibility of addiction and overdose presented by the drugs themselves and the risk of diseases like <a href=\"http:\/\/www.cdc.gov\/hepatitis\/populations\/idu.htm\" target=\"_blank\" rel=\"noopener noreferrer\">Hepatitis<\/a> and <a href=\"http:\/\/www.avert.org\/professionals\/hiv-social-issues\/key-affected-populations\/people-inject-drugs\" target=\"_blank\" rel=\"noopener noreferrer\">HIV<\/a> associated with needle-sharing. We know that supervised injection sites and <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1307729\/\" target=\"_blank\" rel=\"noopener noreferrer\">needle exchanges<\/a> can go far towards mitigating these risks. However, despite the clear benefit of these measures, efforts to implement them have been slow to gain traction, due largely to the <a href=\"http:\/\/www.usnews.com\/news\/articles\/2016-04-20\/a-controversial-response-to-heroin-epidemic-supervised-injections\" target=\"_blank\" rel=\"noopener noreferrer\">social<\/a> <a href=\"http:\/\/www.huffingtonpost.com\/2015\/03\/27\/needle-exchanges-indiana_n_6949734.html\" target=\"_blank\" rel=\"noopener noreferrer\">stigma<\/a> <a href=\"http:\/\/www.nytimes.com\/2016\/03\/23\/nyregion\/fighting-heroin-ithaca-looks-to-injection-centers.html?_r=0\" target=\"_blank\" rel=\"noopener noreferrer\">around<\/a> this issue. As a result, our investment in these potentially lifesaving interventions has not been commensurate with the scale of the threat.<\/p>\n<p>Finally, there is the challenge of Zika; an area where we have had to act decisively on our values of safeguarding population health, even as our knowledge of the disease remains in its adolescence. We are still learning about <a href=\"http:\/\/www.scientificamerican.com\/article\/zika-mystery-case-raises-questions-about-new-transmission-route\/\" target=\"_blank\" rel=\"noopener noreferrer\">how Zika spreads<\/a>, <a href=\"http:\/\/qz.com\/635161\/even-in-the-place-where-zika-virus-was-first-discovered-its-true-origin-is-a-mystery\/\" target=\"_blank\" rel=\"noopener noreferrer\">its origin<\/a>, and <a href=\"http:\/\/fortune.com\/2016\/08\/03\/nih-launches-zika-vaccine-trial\/\" target=\"_blank\" rel=\"noopener noreferrer\">how it can be stopped<\/a>. Despite these unknowns, <a href=\"http:\/\/www.miamiherald.com\/news\/business\/tourism-cruises\/article100848577.html\" target=\"_blank\" rel=\"noopener noreferrer\">the danger of the virus<\/a> means that we cannot delay our interventions until our knowledge is more fully formed. As best we can, we <a href=\"http:\/\/www.cbsnews.com\/news\/florida-starts-aerial-spraying-zika-virus-miami-beach\/\" target=\"_blank\" rel=\"noopener noreferrer\">have<\/a> <a href=\"https:\/\/www.cdc.gov\/zika\/prevention\/\" target=\"_blank\" rel=\"noopener noreferrer\">taken<\/a> <a href=\"http:\/\/wwwnc.cdc.gov\/travel\/page\/zika-information\" target=\"_blank\" rel=\"noopener noreferrer\">action<\/a> to prevent Zika using what we know, while working assiduously to learn what we do not.<\/p>\n<p>We are in the business of safeguarding the health of populations. An appreciation of the dual role of knowledge and values in this regard suggests that we need to work on both axes: improving knowledge and influencing values. The more we know about a problem, the more options we are able to apply towards solving it. At the same time, that knowledge is unlikely to result in much action absent a broad, value-informed consensus on the need for action. That is in no small part why we, to my mind, have as a school articulated our broad aspirational common purpose as \u201cThink. Teach. Do.\u201d\u2014because we shall not be meeting our goals without both generating knowledge (\u201cthinking\u201d) and acting to influence and inflect the public conversation (\u201cdoing\u201d). It is my hope that what we do as a school rises to the challenge on both these axes.<\/p>\n<p>I hope everyone has a terrific week. Until next week.<\/p>\n<p>Warm regards,<\/p>\n<p>Sandro<\/p>\n<p>Sandro Galea, MD, DrPH<br \/>Dean and Robert A. Knox Professor<br \/>Boston University School of Public Health<br \/>Twitter: <a href=\"https:\/\/twitter.com\/sandrogalea\" target=\"_blank\" rel=\"noopener noreferrer\">@sandrogalea<\/a><\/p>\n<p><em>Acknowledgement: I am grateful to Eric DelGizzo and Catherine Ettman for their contributions to this Dean\u2019s Note.<\/em><\/p>\n<p>Previous Dean\u2019s Notes are archived at: <a href=\"https:\/\/www.bu.edu\/sph\/tag\/deans-note\/\">https:\/\/www.bu.edu\/sph\/tag\/deans-note\/<\/a><\/p>\n<p><strong>\u00a0<\/strong><\/p>","protected":false},"excerpt":{"rendered":"<p>Some thoughts on knowledge and values, and how striking a balance between the two can help us create a healthier public.<\/p>\n","protected":false},"author":10951,"featured_media":68217,"comment_status":"closed","ping_status":"open","template":"","meta":{"bu_prepress_billboard":"","_bu_prepress_primary_term":"","_bu_prepress_primary_term_manual":""},"tags":[1729],"bu-publication":[3516],"sphnews-article-category":[3519,3527,3531],"sphnews-topic":[],"bu_edition":[],"media_type":[],"profile_tax":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu-article\/91849"}],"collection":[{"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu-article"}],"about":[{"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/types\/bu-article"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/users\/10951"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/comments?post=91849"}],"version-history":[{"count":10,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu-article\/91849\/revisions"}],"predecessor-version":[{"id":191634,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu-article\/91849\/revisions\/191634"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/media\/68217"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/media?parent=91849"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/tags?post=91849"},{"taxonomy":"bu-publication","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu-publication?post=91849"},{"taxonomy":"sphnews-article-category","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/sphnews-article-category?post=91849"},{"taxonomy":"sphnews-topic","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/sphnews-topic?post=91849"},{"taxonomy":"bu_edition","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu_edition?post=91849"},{"taxonomy":"media_type","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/media_type?post=91849"},{"taxonomy":"profile_tax","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/profile_tax?post=91849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}