{"id":54830,"date":"2014-09-30T13:13:58","date_gmt":"2014-09-30T17:13:58","guid":{"rendered":"https:\/\/www.bu.edu\/sph\/?p=54830"},"modified":"2020-09-17T10:30:05","modified_gmt":"2020-09-17T14:30:05","slug":"contaminated-water-linked-to-pregnancy-complications-study-finds","status":"publish","type":"bu-article","link":"https:\/\/www.bu.edu\/sph\/news\/articles\/2014\/contaminated-water-linked-to-pregnancy-complications-study-finds\/","title":{"rendered":"Contaminated Water Linked to Pregnancy Complications, Study Finds"},"content":{"rendered":"\n<div class=\"wp-prepress-component-metabar sphnews-prepress-layout-metabar\">\n\t<div class=\"wp-prepress-component-metabar-wrapper\">\n\t\t\t\t\t<div class=\"wp-prepress-component-metabar-date\">September 30, 2014<\/div>\n\t\t\n\t\t\t\t<div class=\"wp-prepress-component-metabar-credits\">\n\t\t\t\t\t<\/div>\n\t\t<div class=\"wp-prepress-component-metabar-share js-bu-prepress-share-tools\">\n\t\t\t<span class=\"icon-twitter\"><span>Twitter<\/span><\/span>\n\t\t\t<span class=\"icon-facebook\"><span>Facebook<\/span><\/span>\n\t\t\t<span class=\"icon-action\"><\/span>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n\n\n\t<div class=\"profile-listing-container single-profile-format\">\n\t\t<ul class=\"profile-listing profile-format-single\">\n\n\t\t\t\n\t\t\t\t\n\t\t\t\t<li>\n\t\t\t\t\t<a class=\"sph-profile-basic-card\" href=\"https:\/\/www.bu.edu\/sph\/profile\/ann-aschengrau\/\">\n\n\t\t\t\t\t\t<div class=\"sph-profile-basic-media\">\n\t\t\t\t\t\t\t<div class=\"sph-profile-basic-image\"><figure class=\"profile-photo profile-single-photo\"><img width=\"600\" height=\"600\" src=\"\/sph\/files\/2013\/10\/Ann-Aschengrau-1.jpg\" alt=\"Ann Aschengrau\" \/><\/figure><\/div>\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t<div class=\"sph-profile-basic-content\">\n\n\t\t\t\t\t\t\t<h2 class=\"sph-profile-title\">\n\t\t\t\t\t\t\t\t<span class=\"sph-profile-name\" data-name=\"Ann  Aschengrau\"><span class=\"sph-profile-name-full\">Ann Aschengrau<\/span>, <span class=\"sph-profile-name-degrees\"> ScD<\/span><\/span>\t\t\t\t\t\t\t<\/h2>\n\n\t\t\t\t\t\t\t<h6 class=\"sph-profile-main-position\">\n\t\t\t\t\t\t\t\t<span class=\"sph-profile-main-position\"><span class=\"sph-profile-position-title\"> Professor<\/span><span class=\"sph-profile-position-department\"><span>, <\/span>Epidemiology<\/span> <span class=\"sph-profile-position-institution\"> <span>- <\/span>Boston University School of Public Health<\/span><\/span>\t\t\t\t\t\t\t<\/h6>\n\n\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\n\t\t\t\n\t\t<\/ul>\n\t<\/div><!--\/.profile-listing-->\n\n\n<p>Prenatal exposure to tetrachloroethylene (PCE) in drinking water may increase the risk of stillbirth and placental abruption, according to a new study led by a BUSPH researcher.<\/p>\n<p>The study, published in the journal Environmental Health, compared 1,091 PCE-exposed pregnancies and 1,019 unexposed pregnancies among 1,766 women in Cape Cod, Ma., where water was contaminated in the late 1960s to the early 1980s by the installation of vinyl-lined asbestos cement pipes. PCE exposure was estimated using water-distribution system modeling software. Data on pregnancy complications were self-reported by mothers.<\/p>\n<p>Of the more than 2,000 pregnancies, 9 percent were complicated by pregnancy disorders associated with placental dysfunction. Pregnancies among women with high PCE exposure had 2.38 times the risk of stillbirth and 1.35 times the risk of placental abruption, compared to unexposed pregnancies. Also, the study found an elevated risk of vaginal bleeding in pregnancies where women had PCE exposure greater than or equal to the sample median.<\/p>\n<p>Lead researcher Ann Aschengrau, professor of epidemiology at BUSPH, said the study findings support a small body of prior research indicating that PCE exposure may impact placental function and fetal growth. However, further investigation of related disorders is needed, she said.<\/p>\n<p>\u201cWe need to have a better understanding of the impact of this common drinking water contaminant on all aspects of pregnancy,\u201d said Aschengrau, who has led numerous prior studies on the health effects of PCE.<\/p>\n<p>Researchers used data from the Cape Cod Family Health Study, a population-based retrospective study designed to examine the influence of prenatal exposure to PCE-contaminated drinking water on multiple outcomes during pregnancy and childhood. Women were considered eligible for the parent cohort if they gave birth to at least one child between 1969 and 1983 and were living in one of eight Cape Cod towns with some contaminated pipes at the time of the child\u2019s birth.<\/p>\n<p>The study found no link between PCE exposure and preeclampsia or delivery of small-for-gestational-age (SGA) infants.<\/p>\n<p>\u201cOur results suggest that prenatal PCE exposure is not associated with all obstetric complications, but may increase the risk of certain ones, including stillbirth and placental abruption,\u201d the study says.<\/p>\n<p>The study was conducted as part of BU\u2019s Superfund Research Program. Co-authors include: Dr. Shruthi Mahalingaiah, assistant professor at the BU School of Medicine; Michael Winter, associate director of the BUSPH Data Coordinating Center, and Jenny Carwile, postdoctoral associate in epidemiology at BUSPH.<\/p>\n<p>The study is available here: <a target=\"_blank\" href=\"http:\/\/www.ehjournal.net\/content\/13\/1\/72\" rel=\"noopener noreferrer\"><\/a><a href=\"http:\/\/www.ehjournal.net\/content\/13\/1\/72\">http:\/\/www.ehjournal.net\/content\/13\/1\/72<\/a><\/p>\n<p>Submitted by: <a title=\"Contaminated Water Linked to Pregnancy Complications, Study Finds\" href=\"https:\/\/www.bu.edu\/sph\/2014\/09\/30\/contaminated-water-linked-to-pregnancy-complications-study-finds\/\">Lisa Chedekel<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prenatal exposure to tetrachloroethylene (PCE) in drinking water may increase the risk of stillbirth and placental abruption.<\/p>\n","protected":false},"author":8472,"featured_media":54853,"comment_status":"closed","ping_status":"closed","template":"","meta":{"bu_prepress_billboard":"","_bu_prepress_primary_term":"","_bu_prepress_primary_term_manual":""},"tags":[1535,2261,1536,1537],"bu-publication":[3516],"sphnews-article-category":[3519,3529,3540],"sphnews-topic":[],"bu_edition":[],"media_type":[],"profile_tax":[368],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu-article\/54830"}],"collection":[{"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu-article"}],"about":[{"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/types\/bu-article"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/users\/8472"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/comments?post=54830"}],"version-history":[{"count":8,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu-article\/54830\/revisions"}],"predecessor-version":[{"id":174663,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu-article\/54830\/revisions\/174663"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/media\/54853"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/media?parent=54830"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/tags?post=54830"},{"taxonomy":"bu-publication","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu-publication?post=54830"},{"taxonomy":"sphnews-article-category","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/sphnews-article-category?post=54830"},{"taxonomy":"sphnews-topic","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/sphnews-topic?post=54830"},{"taxonomy":"bu_edition","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/bu_edition?post=54830"},{"taxonomy":"media_type","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/media_type?post=54830"},{"taxonomy":"profile_tax","embeddable":true,"href":"https:\/\/www.bu.edu\/sph\/wp-json\/wp\/v2\/profile_tax?post=54830"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}