EH Seminar-W. MICHAEL CAUDLE, Ph.D.-In Vitro, in Vivo, and Proteomic Approaches to Investigate the Effects of Halogenated Flame Retardants on the Nigrostriatal Dopamine System and Risk of Parkinson's Disease
- 12:00 pm on Friday, January 17, 2014
- 1:00 pm on Friday, January 17, 2014
- Contact Name:
- Jean van Seventer
- Contact Email:
Research in the Caudle lab has focused on investigating the neurological effects of exposure to halogenated compounds, such as insecticides and industrial chemicals, that demonstrate significant levels in our environment as well as human tissue. The majority of these studies have concentrated on the effects of these compounds on the nigrostriatal dopamine system in the context of Parkinson's disease. The lab works with multiple experimental systems in order to gain an enriched understanding of the cellular and molecular targets and pathological cascades involved in flame-retardant mediated damage to dopamine neurons. This online presentation will highlight past, present, and future work with these compounds and the dopamine system and how different experimental models are leveraged to accomplish these goals.