Lawrence Mwananyanda
Profiles

Lawrence Mwananyanda, MD

Adjunct Research Assistant Professor, Global Health - Boston University School of Public Health

(617) 414-1268
lawyanda@bu.edu
Lusaka, Zambia
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Biography

Dr. Lawrence Mwananyanda is a clinician/scientist with a wealth of experience in conducting medical and public health research. He has been Principal Investigator or Co-PI on multiple research project. His portfolio includes being the Director of the HIV Vaccines Trials Unit at the Botswana Harvard Partnership where he and colleagues worked on the first Phase 1 HIV vaccine trials to be conducted in Africa. His interest with HIV vaccines research continued with his stint at the Emory University under the Zambia HIV Research Project where they studied conformational changes of the HIV at infection in a cohort of discordant couples to aid in design of next generation HIV trial vaccines.

With colleagues at Boston University, Dr. Mwananyanda’s focus has been research on child survival. Ongoing research include the Zambia Pertussis RSV Infant Mortality Estimation Study (ZPRIME) Southern Africa Mother Infant Pertussis Study – Nasopharyngeal Carriage (SAMIPS-NPC), Zambia Infant Cohort Study (ZICS) whose overall goal is to determine if HIV-exposed but uninfected infants (HEU) infants born to HIV-infected mothers on antiretroviral therapy have increased morbidity and mortality, and to correlate maternal Immune Activation (with infant clinical outcome, and immune dysregulation as a potential mechanism for the poor HEU outcome. All these studies are based in Lusaka, Zambia. Dr. Mwananyanda is also the Zambia Site Director for the Harvard-Boston University-Northwestern University-New Mexico Fogarty Global Health program.

Education

  • Jagiellonian University, MD Field of Study: Medicine
  • University of Alabama at Birmingham, MPH Field of Study: Epidemiology
  • Jagiellonian University, BSc Field of Study: Biology

Websites

Publications

  • Published on 1/18/2023

    Sialubanje C, Kaiser JL, Ngoma T, Mwananyanda L, Fong RM, Hamer DH, Scott NA. Postnatal care services in rural Zambia: a qualitative exploration of user, provider, and community perspectives on quality of care. BMC Pregnancy Childbirth. 2023 Jan 18; 23(1):39. PMID: 36653751.

     Read At: PubMed
  • Published on 12/6/2022

    Gill CJ, Mwananyanda L, MacLeod WB, Kwenda G, Pieciak RC, Etter L, Bridges D, Chikoti C, Chirwa S, Chimoga C, Forman L, Katowa B, Lapidot R, Lungu J, Matoba J, Mwinga G, Mubemba B, Mupila Z, Muleya W, Mwenda M, Ngoma B, Nakazwe R, Nzara D, Pawlak N, Pemba L, Saasa N, Simulundu E, Yankonde B, Thea DM. What is the prevalence of COVID-19 detection by PCR among deceased individuals in Lusaka, Zambia? A postmortem surveillance study. BMJ Open. 2022 Dec 06; 12(12):e066763. PMID: 36600354.

     Read At: PubMed
  • Published on 11/15/2022

    Osei-Poku GK, Mwananyanda L, Elliot PA, MacLeod WB, Somwe SW, Pieciak RC, Gill CJ. Assessing infant sleep practices and other risk factors of SIDS in Zambia: a cross-sectional survey of mothers in Lusaka, Zambia. BMC Pediatr. 2022 Nov 15; 22(1):660. PMID: 36380292.

     Read At: PubMed
  • Published on 9/15/2022

    Nawa M, Mwansa J, Mwaba J, Kaonga P, Mukubesa AN, Simuyandi M, Chisenga CC, Alabi P, Mwananyanda L, Thea DM, Chilengi R, Kwenda G. Microbiologic and virulence characteristics of Moraxella catarrhalis isolates from Zambian children presenting with acute pneumonia. Pediatr Pulmonol. 2022 Dec; 57(12):3084-3093. PMID: 36056795.

     Read At: PubMed
  • Published on 8/8/2022

    Mazur NI, Terstappen J, Baral R, Bardají A, Beutels P, Buchholz UJ, Cohen C, Crowe JE, Cutland CL, Eckert L, Feikin D, Fitzpatrick T, Fong Y, Graham BS, Heikkinen T, Higgins D, Hirve S, Klugman KP, Kragten-Tabatabaie L, Lemey P, Libster R, Löwensteyn Y, Mejias A, Munoz FM, Munywoki PK, Mwananyanda L, Nair H, Nunes MC, Ramilo O, Richmond P, Ruckwardt TJ, Sande C, Srikantiah P, Thacker N, Waldstein KA, Weinberger D, Wildenbeest J, Wiseman D, Zar HJ, Zambon M, Bont L. Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape. Lancet Infect Dis. 2023 Jan; 23(1):e2-e21. PMID: 35952703.

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  • Published on 5/19/2022

    Li Y, Wang X, Blau DM, Caballero MT, Feikin DR, Gill CJ, Madhi SA, Omer SB, Simões EAF, Campbell H, Pariente AB, Bardach D, Bassat Q, Casalegno JS, Chakhunashvili G, Crawford N, Danilenko D, Do LAH, Echavarria M, Gentile A, Gordon A, Heikkinen T, Huang QS, Jullien S, Krishnan A, Lopez EL, Markic J, Mira-Iglesias A, Moore HC, Moyes J, Mwananyanda L, Nokes DJ, Noordeen F, Obodai E, Palani N, Romero C, Salimi V, Satav A, Seo E, Shchomak Z, Singleton R, Stolyarov K, Stoszek SK, von Gottberg A, Wurzel D, Yoshida LM, Yung CF, Zar HJ, Nair H. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis. Lancet. 2022 05 28; 399(10340):2047-2064. PMID: 35598608.

     Read At: PubMed
  • Published on 5/1/2022

    Park DE, Watson NL, Focht C, Feikin D, Hammit L, Brooks WA, Howie SRC, Kotloff KL, Levine OS, Madhi SA, Murdoch DR, O'Brien KL, Scott JAG, Thea DM, Amorninthapichet T, Awori J, Bunthi C, Ebruke B, Elhilali M, Higdon M, Hossain L, Jahan Y, Moore DP, Mulindwa J, Mwananyanda L, Naorat S, Prosperi C, Thamthitiwat S, Verwey C, Jablonski KA, Power MC, Young HA, Deloria Knoll M, McCollum ED. Digitally recorded and remotely classified lung auscultation compared with conventional stethoscope classifications among children aged 1-59 months enrolled in the Pneumonia Etiology Research for Child Health (PERCH) case-control study. BMJ Open Respir Res. 2022 May; 9(1). PMID: 35577452.

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  • Published on 4/1/2022

    Lohman-Payne B, Koster J, Gabriel B, Chilengi R, Forman LS, Heeren T, Duffy CR, Herlihy J, Crimaldi S, Gill C, Chavuma R, Mwananyanda L, Thea DM. Persistent Immune Activation in Human Immunodeficiency Virus-Infected Pregnant Women Starting Combination Antiretroviral Therapy After Conception. J Infect Dis. 2022 Apr 01; 225(7):1162-1167. PMID: 33780543.

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  • Published on 2/1/2022

    Gill CJ, Mwananyanda L, MacLeod WB, Kwenda G, Pieciak R, Mupila Z, Murphy C, Chikoti C, Forman L, Berklein F, Lapidot R, Chimoga C, Ngoma B, Larson A, Lungu J, Nakazwe R, Nzara D, Pemba L, Yankonde B, Chirwa A, Mwale M, Thea DM. Infant deaths from respiratory syncytial virus in Lusaka, Zambia from the ZPRIME study: a 3-year, systematic, post-mortem surveillance project. Lancet Glob Health. 2022 02; 10(2):e269-e277. PMID: 35063114.

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  • Published on 12/25/2021

    Osei-Poku GK, Thomas S, Mwananyanda L, Lapidot R, Elliott PA, Macleod WB, Somwe SW, Gill CJ. A systematic review of the burden and risk factors of sudden infant death syndrome (SIDS) in Africa. J Glob Health. 2021; 11:04075. PMID: 35003713.

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