David W. Kaufman, ScD

Professor, Epidemiology
David Kaufman
(617) 206-6146dwk@bu.edu
Slone Epidemiology Center
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Biography

David W. Kaufman is Professor of Epidemiology at the Boston University School of Public Health and Director of the Slone Epidemiology Center. He obtained his M.S. and Sc.D. in Epidemiology from Harvard School of Public Health. In 1975 he joined the newly created Drug Epidemiology Unit (now the Slone Epidemiology Center ) as a Research Associate. His early career as an epidemiologist at the DEU was primarily spent in studies of drugs and other factors in relation to cancer, heart disease, and various other conditions. Together with Drs. Slone, Shapiro, and Lynn Rosenberg, he participated in the development of Case-Control Surveillance. In the 1980s, Dr. Kaufman was co-investigator of the International Agranulocytosis and Aplastic Anemia Study, a pioneering effort in the evaluation of these extremely rare but often drug-induced blood dyscrasias that was conducted in seven countries with several hundred cases enrolled. He has directed studies of aplastic anemia in Thailand and the United States. The Thai study is the largest epidemiological investigation of aplastic anemia that has been conducted, with over 500 cases and 2200 controls. Dr. Kaufman pursued his interest in rare drug induced diseases as principal investigator of an international study of Stevens-Johnson syndrome and toxic epidermal necrolysis conducted in four countries in Europe, and a study of anaphylaxis conducted in Spain, Hungary, India, and Sweden. Other major activities have included an international study of analgesics in relation to upper gastrointestinal bleeding and the National Analgesic Nephropathy Study, a multicenter study of end stage renal disease patients in three regions of the U.S. Dr. Kaufman worked closely with Allen Mitchell in the implementation of the Slone Survey, a U.S. population-based survey of medication use. He was principal investigator of a recently completed study that documented an inverse relationship between Oxalobacter formigenes, an oxalate metabolizing bacterium found in the colons of about 40% of the normal population, and calcium oxalate kidney stones. He also directed the Patient Registries at Slone: Myeloma and MDS, a recent nationwide effort that followed patients with the two diseases through the course of their illness. Currently Dr. Kaufman is co-principal investigator for a large scale behavioral surveillance program of acetaminophen users and is involved in other postmarketing surveillance activities. He was Assistant Director of the Slone Epidemiology Unit from 1986 to 1997, and was Associate Director from 1998 to 2016.

Other Positions

  • Director, Slone Epidemiology Center, Boston University Medical Campus

Education

  • Harvard University, ScD
  • Harvard University, MS
  • Bethel College, BA

Publications

  • Published on 3/18/2019

    Kaufman DW, Kelly JP, Battista DR, Malone MK, Weinstein RB, Shiffman S. Five-year trends in acetaminophen use exceeding the recommended daily maximum dose. Br J Clin Pharmacol. 2019 05; 85(5):1028-1034. PMID: 30740763.

    Read at: PubMed
  • Published on 7/21/2018

    Kelly JP, Battista DR, Shiffman S, Malone MK, Weinstein RB, Kaufman DW. Knowledge of dosing directions among current users of acetaminophen-containing medications. J Am Pharm Assoc (2003). 2018 Sep - Oct; 58(5):492-498. PMID: 30041852.

    Read at: PubMed
  • Published on 7/17/2018

    Shiffman S, Battista DR, Kelly JP, Malone MK, Weinstein RB, Kaufman DW. Exceeding the maximum daily dose of acetaminophen with use of different single-ingredient OTC formulations. J Am Pharm Assoc (2003). 2018 Sep - Oct; 58(5):499-504. PMID: 30030041.

    Read at: PubMed
  • Published on 3/25/2018

    Shiffman S, Battista DR, Kelly JP, Malone MK, Weinstein RB, Kaufman DW. Prevalence of exceeding maximum daily dose of paracetamol, and seasonal variations in cold-flu season. Br J Clin Pharmacol. 2018 06; 84(6):1250-1257. PMID: 29516533.

    Read at: PubMed
  • Published on 1/26/2018

    Kaufman DW, Kelly JP, Battista DR, Malone MK, Weinstein RB, Shiffman S. Exceeding the daily dosing limit of nonsteroidal anti-inflammatory drugs among ibuprofen users. Pharmacoepidemiol Drug Saf. 2018 03; 27(3):322-331. PMID: 29372579.

    Read at: PubMed
  • Published on 5/23/2017

    Borgatta L, Kaufman D, Kelly JP, Babaian D, Banks M. Applications for Research Concerning Fetal or Placental Tissue and Expected Institutional Review Board Responses. J Empir Res Hum Res Ethics. 2017 Jul; 12(3):150-160. PMID: 28535711.

    Read at: PubMed
  • Published on 5/1/2016

    Ernst FR, Pocoski J, Cutter G, Kaufman DW, Pleimes D. Analysis of Diagnoses Associated with Multiple Sclerosis-Related In-Hospital Mortality Using the Premier Hospital Database. Int J MS Care. 2016 May-Jun; 18(3):154-61. PMID: 27252603.

    Read at: PubMed
  • Published on 1/1/2016

    Public Policy Committee, International Society of Pharmacoepidemiology. Guidelines for good pharmacoepidemiology practice (GPP). Pharmacoepidemiol Drug Saf. 2016; 25:2-10.

    Read at: Custom
  • Published on 12/11/2015

    Kaufman DW, Kelly JP, Battista DR, Malone MK, Weinstein RB, Shiffman S. Relation of Health Literacy to Exceeding the Labeled Maximum Daily Dose of Acetaminophen. Am J Prev Med. 2016 Jun; 50(6):e183-e190. PMID: 26689980.

    Read at: PubMed
  • Published on 7/7/2015

    Shiffman S, Rohay JM, Battista D, Kelly JP, Malone MK, Weinstein RB, Kaufman DW. Patterns of acetaminophen medication use associated with exceeding the recommended maximum daily dose. Pharmacoepidemiol Drug Saf. 2015 Sep; 24(9):915-21. PMID: 26149538.

    Read at: PubMed

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