{"id":547,"date":"2012-11-29T11:55:08","date_gmt":"2012-11-29T16:55:08","guid":{"rendered":"https:\/\/www.bu.edu\/slone\/?page_id=547"},"modified":"2015-02-11T16:23:58","modified_gmt":"2015-02-11T21:23:58","slug":"breast-cancer-subtypes","status":"publish","type":"page","link":"https:\/\/www.bu.edu\/slone\/research\/studies\/breast-cancer-subtypes\/","title":{"rendered":"Epidemiology of Breast Cancer Subtypes in African-American Women"},"content":{"rendered":"

The purpose of this collaborative Program Project is to understand the etiology of specific subtypes of breast cancer in African American women, in particular, the basal-like subtype, which occurs about twice as often in African American women as in other ethnic groups and is associated with a worse prognosis than other subtypes.\u00a0\u00a0 Questionnaire, genetic, and pathology data from four large epidemiologic studies, including the Black Women\u2019s Health Study (BWHS)<\/a>, will be pooled in order to have sufficient numbers of cases of the basal-like subtype.\u00a0 The data coordinating center will reside at the Slone Epidemiology Center.\u00a0 Archived tumor blocks will be requested from the pathology departments of hospitals where study participants receive treatments.\u00a0 Tumor tissue microarrays will be created and the tissue will be assayed by immunohistochemistry to establish the subtypes.\u00a0 Both non-genetic and genetic factors will be assessed in relation to breast cancer subtypes.\u00a0 In addition, analyses of gene-environment interactions will be carried out.<\/p>\n

Investigators and Study Staff<\/h3>
<\/p>\n

Investigators: <\/strong><\/p>\n

Julie R. Palmer, Sc.D., Principal Investigator
\nSlone Epidemiology Center<\/p>\n

Christine Ambrosone, Ph.D., Principal Investigator
\nRoswell Park Cancer Institute<\/p>\n

Andrew Olshan, M.D.
\nUniversity of North Carolina Lineberger Cancer Center<\/p>\n

Lynn Rosenberg, Sc.D., Co-Investigator
\nSlone Epidemiology Center<\/p>\n

Edward Ruiz-Narv\u00e1ez, Sc.D., Co-Investigator
\nSlone Epidemiology Center<\/p>\n

Patricia F. Coogan, D.Sc., Co-Investigator
\nSlone Epidemiology Center<\/p>\n

Kathryn Lunetta, Sc.D.,
\nDirector of Biostatistics and Data Management Core
\nBoston University School of Public Health<\/p>\n

Study Staff:<\/strong><\/p>\n

Traci Bethea, Postdoctoral Fellow
Katie McInerney, Data Manager
\nStephen Haddad, Data Analyst
\nHannah Lord, Research Supervisor
\nJackie Smith, Research Nurse
\nSharon Cornelius, Research Assistant
\nOleg Starobinets, Systems Analyst<\/p>\n

<\/div>\n<\/div>\n\n

Study Details<\/h3>
<\/p>\n

Source of Funding:<\/strong><\/p>\n

National Cancer Institute<\/p>\n

Study Period:<\/strong><\/p>\n

2011 to 2016<\/p>\n

<\/div>\n<\/div>\n\n

Contact Information<\/h3>
<\/p>\n

Email Julie R. Palmer, Sc.D., at jpalmer@bu.edu<\/a><\/p>\n

<\/div>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"

The purpose of this collaborative Program Project is to understand the etiology of specific subtypes of breast cancer in African American women, in particular, the basal-like subtype, which occurs about twice as often in African American women as in other ethnic groups and is associated with a worse prognosis than other subtypes.\u00a0\u00a0 Questionnaire, genetic, and […]<\/p>\n","protected":false},"author":4351,"featured_media":0,"parent":37,"menu_order":80,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/slone\/wp-json\/wp\/v2\/pages\/547"}],"collection":[{"href":"https:\/\/www.bu.edu\/slone\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bu.edu\/slone\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/slone\/wp-json\/wp\/v2\/users\/4351"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/slone\/wp-json\/wp\/v2\/comments?post=547"}],"version-history":[{"count":13,"href":"https:\/\/www.bu.edu\/slone\/wp-json\/wp\/v2\/pages\/547\/revisions"}],"predecessor-version":[{"id":2447,"href":"https:\/\/www.bu.edu\/slone\/wp-json\/wp\/v2\/pages\/547\/revisions\/2447"}],"up":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/slone\/wp-json\/wp\/v2\/pages\/37"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/slone\/wp-json\/wp\/v2\/media?parent=547"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}