Call for Proposals: Lung Cancer Research
We are seeking to fund pilot programs focused on preventing, intercepting, or curing lung cancer at early stages. Research teams from across BU are invited to apply.
Pre-proposals are due by Friday, July 23. Projects will be selected by a joint steering committee for funding up to a maximum of $250,000 (inclusive of indirect costs) per year, with the opportunity to renew for a second year.
Research Focus
Proposals should be focused on preventing, intercepting, or curing lung cancer at early stages and should consider the concepts that lung cancer is often caused by chronic exposure to respiratory carcinogens that produce cellular/genomic damage, chronic inflammation, and alterations in innate/adaptive immunity—all may trigger the escape of transformed cells from immune surveillance.
Additionally, proposals of interest could include: orthotopic lung cancer animal models (small and large animals) for investigating treatments, intratumoral injection technologies (e.g., formulation, delivery device, procedure enablers), characterization of immunogenic cell death pathways, as well as the use of analytics to develop algorithms to better predict healthcare outcomes (e.g., risk of disease/recurrence).
Proposals that characterize the biology of premalignant lesions, early (resectable) lung cancers, or that substantially improve the detection and treatment of lung cancer at more curable, early stages will also be prioritized for funding. Proposals that investigate immunological changes to the tumor microenvironment after chemotherapy or radiotherapy in advanced diseased will be considered.
Proposal Process
This RFP involves a two-stage process for submission and review of applications. Following the initial pre-proposal deadline, the joint steering committee will identify promising pre-proposals to be expanded into full proposals.
View details about the proposal process and download the full RFP and pre-proposal template on the Industry Engagement website (Kerberos log-in required).