Christopher Chen, M.D., Ph.D. Professor (BME, MSE)
Education A.B., Biochemistry, Harvard College
M.S., Mechanical Engineering, Massachusetts Institute of Technology
Ph.D., Medical Engineering and Medical Physics, Harvard-MIT Health Sciences and Technology Program.
M.D., Harvard Medical SchoolPrimary Appointment William F. Warren Distinguished Professor of Biomedical EngineeringAdditional Affiliations Founding Director, Biological Design Center (BDC)
The Wyss Institute for Biologically Inspired Engineering at Harvard University
Division of Materials Science & Engineering
Deputy Director of the NSF Engineering Research Center in Cellular Metamaterials
Co-PI of the NSF Science and Technology Center for Engineering Mechanobiology
Director, SB2 NIH/NIGMS T32 Training Program
In the News
With an NSF grant, a BU program will train a diverse group of PhD students for tomorrow’s workforce in biotech, synthetic biology, and other sectors. [ More ]
Recognition for pioneering cures for heart attacks, liver disease, and more.
[ More ]
Convergent Themes
Christopher Chen is an active interdisciplinary researcher in the following area:
Synthetic Biology, Tissue Engineering, & Mechanobiology |͟↗̱|
Our research transcends disciplines across Boston University and the College of Engineering, drawing upon diverse thinking to solve societal challenges.
Areas of Interest Vascular, Cardiac, and Stem Cell Biology and Engineering; Mechanobiology; Micro- and Nanotechnology; Biomaterials; Cell Adhesion and Extracellular Matrix
Research Areas Prof. Chen’s laboratory seeks
1) to understand how adhesive, mechanical, and biochemical interactions drive cell and tissue function
2) to use this knowledge to build biomimetic tissues as experimental models of disease and physiology
3) to direct tissue remodeling and regeneration
Prof. Chen is studying how the cooperation between adhesive, mechanical and biochemical signaling drives tissues to organize during development, adapt to physical stresses, and devolve during disease. Dr. Chen’s laboratory examines these questions through the development and application of innovative technologies to control how cells interact with their surroundings, advancing numerous technologies from microfluidics, microelectromechanical systems (MEMS), nanofabrication, mechanobiology, biomaterials, and synthetic and stem cell biology. Dr. Chen’s research applies insights from these efforts to the biology and engineering of stem cells, tissue vascularization, cardiac tissue, and cancer.
At this interface between technology, cell biology, and medicine, Chen and his lab’s mission is to provide new tools for biomedicine, to gain new insights into the control of cell and tissue function, to train scientific leaders that transcend traditional disciplines, and to demonstrate the boundless opportunities for impacting the future of research, medicine, and education.
Publications
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