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Mouse Assisted Reproductive Technology (MART) Core

Last updated on June 3, 2024 4 min read Working with Animal Subjects - Mouse Assisted Reproductive Technology (MART) Core

Overview

Boston University Mouse Assisted Reproductive Technology (MART) Core is part of the BU Animal Science Center (ASC) with a mandate not only to oversee the breeding of complex genetically modified mice, but also to generate and preserve rare and valuable strains for later use.

The MART core maintains a large repository of frozen sperm and embryo collections for the research community that can be revived anytime to generate live mice. MART core staff are experienced in collecting mouse sperm, recovery of unfertilized and fertilized eggs, conducting in-vitro fertilization and embryo transfer (ET). In addition, in order to eliminate common mouse pathogens detected in offspring born to mice of uncertain health status (for example, mice coming from other facilities and countries), we perform a number of rederivations, notably IVF, embryo transfer as well as cesarean section and neonatal cross-fostering rederivations. All of the above procedures are conducted in our barrier facilities to preserve the specific pathogen-free health status of our mouse colonies and breeding program.

If you have a breeding or model generation issue that does not fall under our listed services or you are not sure which services may best fit your goals, please reach out, and we’d be happy to assist.

Services

2024 Pricing for Services

BU PIs External
Sperm Collection and Cryopreservation$698$1,243
In Vitro Fertilization (IVF) Rederivation$1,591$2,833
Embryo Transfer Rederivation$1,884$3,354
Cesarean Cross-Fostering Rederivation$2,001$3,563
Neonatal Rederivation and Cross-fostering Rederivation$1,939$3,453
Embryo Collection and Cryopreservation$1,315$2,341
Blastocyst Complementation: Mouse model generation for gene function assessment$1,500$1,500
Transgenic Technology and Assisted Reproductive Technology Practicum: Training module for graduate students and the BU community$1,400$1,400
Sperm and Embryo Banking: Storage/ line/ year$197$350

More Information

Contact

Colleen Thurman
Director, Animal Science Center
cthurman@bu.edu

John Mkandawire
MART Core Services Specialist
(617) 358-8429│FAX (617) 358-8277 │jmmn@bu.edu

Mailing Address:

Mouse Assisted Reproductive Technology Core
Boston University Medical Center
700 Albany St., W707
Boston, MA 02118

Disclaimer: Reproductive performance of each MART service tends to vary with intrinsic strain viability.

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