Search Results for: chemical containment level program

Chemical Containment Levels (CCL) for Animal Administration

To Print or Save: Download the guidance below as a PDF Introduction/Background This program is intended to provide a standardized, risk-assessment based approach to engineering controls, PPE, and husbandry in BU’s animal spaces for work with rodents. Other animals (i.e., birds, aquatic species, sheep, pigs, non-human primates) will require additional risk assessment to determine an […]

Comprehensive Risk-Based Laboratory Inspection Program

Prepared by: Environmental Health & Safety 1. Introduction Academic research and teaching laboratories at Boston University (BU) and Boston Medical Center (BMC) use a variety of hazardous materials (e.g., chemical, biological, radiological), perform procedures with potential risks, use laboratory equipment (e.g., centrifuges, x-rays, lasers) that pose potential hazards, or pose risks of fire and life […]

Chemical Hygiene Plan

To Print or Save: Download the guidance below as a PDF. Approved Mar 1, 2023 Introduction Purpose Boston University (BU) is committed to the safe and compliant use of chemicals in the laboratory. The Chemical Hygiene Plan (CHP) sets forth the policies, procedures and guidelines in place to protect laboratory workers (and those supporting laboratories at […]

Chemical Labeling

Globally Harmonized System Compliance Guidance Effective June 1st, 2016 All secondary (non –manufacturer) containers of hazardous chemicals MUST adhere to the Global Harmonizes System (GHS) format. All relevant information can be found in section 2 of the Safety Data Sheet, titled Hazard Identification. New GHS compliant label must include the following: Product Identifier (ingredient disclosure): […]

Appendix B: Laboratory Ventilation and Containment for Biosafety

Laboratory-ventilated containment equipment fall into three (3) major categories: Laboratory Chemical (Fume) Hoods Traditional laboratory chemical (or fume) hoods are designed to capture and control chemical vapors and pull them away from the worker. Although the inward flow of air protects the user, chemical hoods do not protect the product (the desired organism being manipulated). […]

Appendix C: Autoclave Quality Assurance Program

Autoclaving is an accepted procedure for the decontamination of certain biohazardous waste. Biological cultures and stocks, contaminated solid waste, and liquid waste can be sterilized through autoclaving. After sterilization in a steam autoclave, these materials are considered non-infectious. All autoclaved waste is placed into the solid biohazard waste stream. Wastes from the BSL4 and BSL3 […]

Appendix D: Biosafety Level 2 (BSL2) Requirements

Biosafety Level 2 (BSL2) is suitable for experiments involving agents of moderate potential hazard to personnel and the environment. For example: Microorganisms of low biohazard potential, such as those in Risk Group 2 or BSL2. Recombinant DNA activity requiring BSL2 physical containment including animal studies that involve the construction of transgenic animals. Non-recombinant cell and/or […]

Chapter 1: Biological Safety Program: Purpose, Scope, and Responsibilities

Purpose The purpose of this Biosafety Manual is to define policies and procedures pertaining to use of biological materials in research at Boston University (BU) and Boston Medical Center (BMC). The policies and procedures within this document are designed to safeguard personnel and the environment from biologically hazardous materials without unduly limiting academic research. This […]

Highly Hazardous Chemicals Program Guidance Document

Approved: January 2022 To Print or Save: Download the guidance below as a PDF 1. Purpose Boston University (BU) is committed to the safe and compliant use of highly hazardous chemicals (HHCs) in the laboratory. This document sets forth procedures and guidelines in place to protect laboratory workers, those supporting laboratories at BU, and students […]

Prions Agent Information Sheet

Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Agent Prion diseases are a variety of neurodegenerative diseases which affect humans, as well as both domestic and wild animal species.  In prion diseases, a cellular prion protein (PrPc) normally found in humans is transformed into a pathogenic isoform (PrPSc) upon exposure to a misfolded prion […]

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