URL: https://grants.nih.gov/grants/guide/rfa-files/RFA-ES-25-002.html
Objectives
The NIEHS Environmental Health Sciences Core Centers (EHSCC) Program aims to foster understanding of human health effects of exposure to environmental agents. An EHSCC is expected to support innovation and be on the cutting edge of science. As such, research activities should cross a variety of disciplines to bring multiple perspectives and approaches to bear on significant environmental health research questions and health impacts. The overall goal of an EHSCC is to identify and capitalize on emerging issues that advance improving the understanding of the relationships among environmental exposures, human biology, and disease.
As intellectual hubs for environmental health science research, the EHSCC are expected to be the thought leaders for the field and advance the goals of the 2025-2029 NIEHS Strategic Plan. The Core Centers provide critical research infrastructure, shared facilities, services and/or resources, to groups of investigators conducting environmental health sciences research. Ultimately the EHSCC should create a flexible structure that allows center members with different expertise to come together to answer complex and/or emerging questions, capitalize on the latest scientific trends, and accelerate the translation of research.
Additionally, community engagement and multi-directional communication should play an essential role to advance the goals and relevance of an EHSCC. Therefore, the structure of the Center should facilitate multi-directional interaction with communities (broadly defined) and EHSCC members through the required Community Engagement Core (CEC).
Funding Information
Up to $850,000 in direct costs per year for up to 4 years ($3.4 million total).
Eligibility
Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support.
Internal Selection Process
BU may submit one proposal.
Interested applicants should submit the following materials via InfoReady Review by: 10/13/2026
- Proposal Summary (2 pages max) describing the central theme of the center and its relevance to environmental health, the goals and directions for the planned projects, and the significance of the research for environmental health sciences. References/citations may be included on one additional page.
- List of proposed collaborators
As necessary, a faculty committee will review internal applications and select an institutional proposal.
Deadlines
Internal Materials Due: Tuesday, October 13, 2026 by 11:59 pm ET
Anticipated Notification Date: Friday, October 30, 2026
External Materials Due: Tuesday, April 20, 2027