{"id":1987,"date":"2022-06-28T16:36:06","date_gmt":"2022-06-28T20:36:06","guid":{"rendered":"https:\/\/www.bu.edu\/photonics-ret\/?page_id=1987"},"modified":"2022-06-28T16:36:06","modified_gmt":"2022-06-28T20:36:06","slug":"mohamed-azize","status":"publish","type":"page","link":"https:\/\/www.bu.edu\/photonics-ret\/research-projects\/projects-2025\/2022-summer-projects\/mohamed-azize\/","title":{"rendered":"Mohamed Azize"},"content":{"rendered":"

Lab-on-chip for Molecular\u00a0Diagnosis\u00a0<\/strong><\/h3>\n

PROJECT DESCRIPTION
\n<\/strong>The Analog Devices Inc. (ADI) team in the Business Innovation Center (BIC) at the Photonics Center provides a case study in how ADI executes intrapreneurship with their Analog Garage model. Now known as NTDHC, the team is focused on developing the next generation of Biosensor platform-on-chip for diagnostics and therapeutics. To deliver point-of-care, low-cost, rapid, disposable diagnostics that don\u2019t require sample prep and still having molecular accuracy to \u201cgold standard\u201d techniques requires a skilled team with expertise across multiple disciplines. Being part of a larger organization, NTDHC can draw from ADI\u2019s expertise in Biology, Chemistry and Materials Science as well as ADI\u2019s analog\/mixed signal electronics expertise and capabilities in device manufacturing.<\/p>\n

Here in this project is proposed a disruptive low-cost & rapid disposable instrument-free route to develop disposable nanoLab-on-a-chip for molecular diagnostic to tackle the current COVID 19 Pandemic and beyond. Conventional Electrochemistry methods will be used to characterize the electro-chemical nanomaterial-based sensor.<\/p>\n

Such a novel disposable biosensor device would be a promising alternative to the current gold standard of reverse transcription-polymerase chain reaction (RT-PCR) and to the other emerging nanotechnology-based diagnostic testing systems. The instrument-free MDx could pave the way for an efficient transformation of the Digital Health Care industry.<\/p>\n

The summer research participant will be in charge to evaluate the multiple optical and EC sensor used by the competition prior to performing a benchmark study (e.g. COVID 19) with the ADI EC nanomaterial-based sensor. Furthermore, a novel bacteria use case will be explored using the ADI EC nanomaterial-based sensor.<\/p>\n

LABORATORY MENTOR
\n<\/strong>Hari Chauhan<\/p>\n

RESEARCH GOALS
\n<\/strong>\u2013 Competition landscape in Molecular diagnostic
\n\u2013 Develop a lab-on-chip method for benchmarking internally the different biosensors used in MDx
\n\u2013 Development of low cost Cartridge for Molecular assays
\n\u2013 A novel bacteria use case to be explored and characterized using ADI nano-sensor versus conventional methods<\/p>\n

LEARNING GOALS
\n<\/strong>– Learn about Optical &Electrical characterization for Molecular assays as well as nanomaterial used for Biosensors
\n\u2013 Learn about the design and fabrication of Biosensors chips in cleanroom
\n\u2013 Learn about SolidWorks, laser cutting and 3D printing for quick prototyping
\n\u2013 Learn about how teamwork is organized in a large US corporation vs a startup company
\n\u2013 Learn about Entrepreneur vs Intrapreneur<\/p>\n

Learn more about\u00a0Mohamed Azize on his faculty page.<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Lab-on-chip for Molecular\u00a0Diagnosis\u00a0 PROJECT DESCRIPTION The Analog Devices Inc. (ADI) team in the Business Innovation Center (BIC) at the Photonics Center provides a case study in how ADI executes intrapreneurship with their Analog Garage model. Now known as NTDHC, the team is focused on developing the next generation of Biosensor platform-on-chip for diagnostics and therapeutics. […]<\/p>\n","protected":false},"author":19768,"featured_media":0,"parent":1983,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/photonics-ret\/wp-json\/wp\/v2\/pages\/1987"}],"collection":[{"href":"https:\/\/www.bu.edu\/photonics-ret\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bu.edu\/photonics-ret\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-ret\/wp-json\/wp\/v2\/users\/19768"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-ret\/wp-json\/wp\/v2\/comments?post=1987"}],"version-history":[{"count":1,"href":"https:\/\/www.bu.edu\/photonics-ret\/wp-json\/wp\/v2\/pages\/1987\/revisions"}],"predecessor-version":[{"id":1988,"href":"https:\/\/www.bu.edu\/photonics-ret\/wp-json\/wp\/v2\/pages\/1987\/revisions\/1988"}],"up":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-ret\/wp-json\/wp\/v2\/pages\/1983"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/photonics-ret\/wp-json\/wp\/v2\/media?parent=1987"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}