{"id":6615,"date":"2024-05-01T09:00:01","date_gmt":"2024-05-01T13:00:01","guid":{"rendered":"https:\/\/www.bu.edu\/photonics-programs\/?p=6615"},"modified":"2025-09-10T11:17:51","modified_gmt":"2025-09-10T15:17:51","slug":"population-responses-of-living-neural-networks-to-periodic-drive","status":"publish","type":"post","link":"https:\/\/www.bu.edu\/photonics-programs\/2024\/05\/01\/population-responses-of-living-neural-networks-to-periodic-drive\/","title":{"rendered":"Population Responses of Living Neural Networks to Periodic Drive"},"content":{"rendered":"<h3>Mentors<\/h3>\n<table width=\"357\" height=\"42\" style=\"border: 2px solid white; margin-bottom: 0;\">\n<tbody>\n<tr>\n<td style=\"border: 2px solid white;\">\n\t<ul class=\"profile-listing profile-format-basic\">\n\t\t\t\t\t\n<li class=\"profile-item profile-item-basic has-title post-4531 profile type-profile status-publish hentry departments-bme departments-pbs affiliation-faculty program-year-yr-2017 program-year-yr-2019 program-year-yr-2022 program-year-yr-2024\">\n\t<a href=\"https:\/\/www.bu.edu\/photonics-programs\/profile\/john-white\/\" class=\"profile-link profile-link-basic\">\n\t\t\t\t\t<figure class=\"profile-photo profile-photo-basic\"><img width=\"150\" height=\"150\" src=\"\/photonics-programs\/files\/2025\/04\/john_white-300x300.png\" alt=\"\" \/><\/figure>\t\t\t\t<h6 class=\"profile-name profile-name-basic\">John White<\/h6>\n\t\t<p class=\"profile-title profile-title-basic\">Professor, BME, Pharmacology and Experimental Therapeutics, Neuroscience<\/p>\t<\/a>\n\n\t\n<\/li>\n\t\t\t<\/ul>\n\t<\/td>\n<td style=\"border: 2px solid white;\">\n\t<ul class=\"profile-listing profile-format-basic\">\n\t\t\t\t\t\n<li class=\"profile-item profile-item-basic has-title post-6771 profile type-profile status-publish hentry departments-bme affiliation-graduate-student program-year-yr-2024\">\n\t<a href=\"https:\/\/www.bu.edu\/photonics-programs\/profile\/brandon-williams\/\" class=\"profile-link profile-link-basic\">\n\t\t\t\t\t<figure class=\"profile-photo profile-photo-basic\"><img width=\"150\" height=\"150\" src=\"\/photonics-programs\/files\/2025\/04\/brandon_williams-300x300.jpg\" alt=\"\" \/><\/figure>\t\t\t\t<h6 class=\"profile-name profile-name-basic\">Brandon Williams<\/h6>\n\t\t<p class=\"profile-title profile-title-basic\">PhD Candidate<\/p>\t<\/a>\n\n\t\n<\/li>\n\t\t\t<\/ul>\n\t<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 style=\"margin-top: 0;\">Project Description<\/h3>\n<p>The hippocampal formation (HF) in mammals is responsible for collecting information about the sensory world and, if appropriate, storing that information as memories, to be offloaded to other brain structures later. The HF has a number of notable response properties, including nested, quasi-periodic activity. In this project, the student will work with us to collect and analyze data related to responses to periodic drive, collected via novel microscopy and voltage-imaging methods.<\/p>\n<div class=\" bu-callout alignright\"><img loading=\"lazy\" src=\"\/photonics-programs\/files\/2025\/01\/20240801_REU-Lab-Headshots-Lea-001-636x424.jpg\" alt=\"\" width=\"636\" height=\"424\" class=\"alignnone size-medium wp-image-5958\" srcset=\"https:\/\/www.bu.edu\/photonics-programs\/files\/2025\/01\/20240801_REU-Lab-Headshots-Lea-001-636x424.jpg 636w, https:\/\/www.bu.edu\/photonics-programs\/files\/2025\/01\/20240801_REU-Lab-Headshots-Lea-001-1024x683.jpg 1024w, https:\/\/www.bu.edu\/photonics-programs\/files\/2025\/01\/20240801_REU-Lab-Headshots-Lea-001-768x512.jpg 768w, https:\/\/www.bu.edu\/photonics-programs\/files\/2025\/01\/20240801_REU-Lab-Headshots-Lea-001-1536x1024.jpg 1536w, https:\/\/www.bu.edu\/photonics-programs\/files\/2025\/01\/20240801_REU-Lab-Headshots-Lea-001-2048x1365.jpg 2048w\" sizes=\"(max-width: 636px) 100vw, 636px\" \/><\/p>\n<h3>Research Participant<\/h3>\n<p><span style=\"color: #808080;\"><em>Program: MSE REU\u00a0<\/em><\/span><\/p>\n<p>Hear what Anastasiia Rudaeva&#8217;s taking with her from her time at BU.<br \/>\n<a href='#' class='button button'>Learn More<\/a><\/div>\n<div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h3 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">Research Goals<\/h3><div class=\"bu_collapsible_section\" style=\"display: none;\">\n<ul>\n<li>Biological preparations for in vitro recordings.<\/li>\n<li>Novel confocal microscopy methods.<\/li>\n<li>Introduction of genetically encoded agents for imaging membrane potential in neurons with cellular resolution.<\/li>\n<li>Analysis of imaging data.<\/li>\n<li>Post-hoc imaging analysis to identify specific neuronal cell types in the preparation.<\/div>\n<\/div>\n<\/li>\n<\/ul>\n<div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h3 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">Learning Goals<\/h3><div class=\"bu_collapsible_section\" style=\"display: none;\">\n<ul>\n<li>Lab safety.<\/li>\n<li>Humane use of experimental animals.<\/li>\n<li>Applied molecular biology.<\/li>\n<li>Advanced microscopy.<\/li>\n<li>Signal processing methods.<\/li>\n<li>Image registration.<\/div>\n<\/div>\n<\/li>\n<\/ul>\n<h3>Timeline<\/h3>\n<p><span style=\"color: #003366;\"><strong>Weeks 1-4:<\/strong><\/span> Safety and animal-use training, shadowing Mr. Williams.<br \/>\n<span style=\"color: #003366;\"><strong>Weeks 5-8:<\/strong><\/span> Participating in experiments, ownership of data processing sub-projects.<br \/>\n<span style=\"color: #003366;\"><strong>Weeks 9-10:<\/strong><\/span> Preparation for the presentation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mentors Project Description The hippocampal formation (HF) in mammals is responsible for collecting information about the sensory world and, if appropriate, storing that information as memories, to be offloaded to other brain structures later. The HF has a number of notable response properties, including nested, quasi-periodic activity. In this project, the student will work with [&hellip;]<\/p>\n","protected":false},"author":22960,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[118],"tags":[125,137,67],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/posts\/6615"}],"collection":[{"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/users\/22960"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/comments?post=6615"}],"version-history":[{"count":4,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/posts\/6615\/revisions"}],"predecessor-version":[{"id":8088,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/posts\/6615\/revisions\/8088"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/media?parent=6615"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/categories?post=6615"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/tags?post=6615"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}