{"id":10794,"date":"2026-03-04T10:25:36","date_gmt":"2026-03-04T15:25:36","guid":{"rendered":"https:\/\/www.bu.edu\/photonics-programs\/?p=10794"},"modified":"2026-03-04T20:14:10","modified_gmt":"2026-03-05T01:14:10","slug":"lookadoo","status":"publish","type":"post","link":"https:\/\/www.bu.edu\/photonics-programs\/2026\/03\/04\/lookadoo\/","title":{"rendered":"Electrode Design for Integrated Flow Metering in Microfluidics"},"content":{"rendered":"<h3>Mentors<\/h3>\n\n\t<ul class=\"profile-listing profile-format-advanced\">\n\t\t\t\t\t\n<li class=\"profile-item profile-item-advanced has-title post-4523 profile type-profile status-publish hentry departments-bme departments-me affiliation-business-innovation-center program-year-yr-2021 program-year-yr-2022 program-year-yr-2023 program-year-186\">\n\t<a href=\"https:\/\/www.bu.edu\/photonics-programs\/profile\/daniel-lookadoo\/\" class=\"profile-link profile-link-advanced\">\n\t\t\t\t\t<figure class=\"profile-photo profile-photo-advanced\"><img width=\"150\" height=\"150\" src=\"\/photonics-programs\/files\/2025\/04\/daniel_lookadoo-300x300.jpg\" alt=\"\" \/><\/figure>\t\t\t\t<h6 class=\"profile-name profile-name-advanced\">Daniel Lookadoo<\/h6>\n\t\t<p class=\"profile-title profile-title-advanced\">Chief Scientific Officer, StataDX<\/p>\t<\/a>\n\n\t\n<\/li>\n\t\t\t\t\t\n<li class=\"profile-item profile-item-advanced post-8217 profile type-profile status-publish hentry affiliation-graduate-student program-year-186 profile-field-mentor\">\n\t<a href=\"https:\/\/www.bu.edu\/photonics-programs\/profile\/hilena-frew-2\/\" class=\"profile-link profile-link-advanced\">\n\t\t\t\t\t<figure class=\"profile-photo profile-photo-advanced\"><img width=\"150\" height=\"150\" src=\"\/photonics-programs\/files\/2025\/09\/IMG_20180921_162131_1-225x300-1.jpg\" alt=\"\" \/><\/figure>\t\t\t\t<h6 class=\"profile-name profile-name-advanced\">Hilena Frew<\/h6>\n\t\t\t<\/a>\n\n\t\n<\/li>\n\t\t\t<\/ul>\n\t\n<h3><span data-preserver-spaces=\"true\">Project Description<\/span><\/h3>\n<div>\n<p>Our research lab, in Boston University Photonics Center\u2019s Business Innovation Center, is focused on the development of new diagnostic tests to support personalized therapeutic strategies for patients suffering from neurological conditions. Given the increasingly decentralized nature of healthcare and clinical trials, there is a need for easy-to-use, cost-effective remote monitoring tools in near-patient settings. To address this unmet need, we are focused on developing an electrochemical-based microfluidic platform to bridge the gap between multiple-biomarker strategies\u2014that are more optimistic with complex, multifactorial diseases\/conditions\u2014and their implementation as a part of routine clinical care\/trials. Our platform\u2014based on novel electrochemical sensing technology developed at Harvard University\u2019s Wyss Institute\u2014selectively detects protein biomarkers captured by antibodies that are coupled to a nano-composite coating on the electrode surface. The goal of this project will be to design and optimize an electrode chip that integrates impedance-based flow metering to support reliable remote monitoring of Multiple Sclerosis disease activity. Researchers working on this project will learn about the application of protein biomarkers for neurological conditions and some of the interdisciplinary challenges associated with developing near-patient diagnostics.<\/p>\n<h3><span data-preserver-spaces=\"true\">Research goals\u00a0<\/span><\/h3>\n<div>\n<p>\u25cf Design and characterize an electrode chip for impedance-based flow metering.<br \/>\n\u25cf Optimize electrode geometry and measurement parameters to maximize signal contrast.<br \/>\n\u25cf Interpret time-dependent impedance signals to identify flow-state transitions.<\/p>\n<h3><span data-preserver-spaces=\"true\">Learning goals\u00a0<\/span><\/h3>\n<div>\n<p>\u25cf Learn about the design and fabrication of electrode chips.<br \/>\n\u25cf Learn about the physics of laminar microfluidic flow and mass transport.<br \/>\n\u25cf Learn about electrochemical impedance spectroscopy and tools for signal processing.<\/p>\n<h3><span data-preserver-spaces=\"true\">Rough Timeline for the Project<\/span><\/h3>\n<div>\n<p>\u00a0Ten weeks, June 1st \u2013 August 7th:<br \/>\n1. Introduction and general lab training<br \/>\n2. Review the literature and ideate design<br \/>\n3. Develop electrode chip design<br \/>\n4. Characterize impedance under static conditions<br \/>\n5. Characterize Impedance under controlled flow<br \/>\n6. Optimize geometry and measurement parameters<br \/>\n7. Refine flow metering algorithm<br \/>\n8. Evaluate design and flow metering performance<br \/>\n9. Make conclusions and report results<br \/>\n10. Prepare and present findings<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Mentors Project Description Our research lab, in Boston University Photonics Center\u2019s Business Innovation Center, is focused on the development of new diagnostic tests to support personalized therapeutic strategies for patients suffering from neurological conditions. Given the increasingly decentralized nature of healthcare and clinical trials, there is a need for easy-to-use, cost-effective remote monitoring tools in [&hellip;]<\/p>\n","protected":false},"author":5736,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/posts\/10794"}],"collection":[{"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/users\/5736"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/comments?post=10794"}],"version-history":[{"count":4,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/posts\/10794\/revisions"}],"predecessor-version":[{"id":10800,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/posts\/10794\/revisions\/10800"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/media?parent=10794"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/categories?post=10794"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bu.edu\/photonics-programs\/wp-json\/wp\/v2\/tags?post=10794"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}