{"id":1395,"date":"2023-05-09T15:25:57","date_gmt":"2023-05-09T19:25:57","guid":{"rendered":"https:\/\/www.bu.edu\/odbl\/?page_id=1395"},"modified":"2024-06-21T15:37:50","modified_gmt":"2024-06-21T19:37:50","slug":"xray-imaging","status":"publish","type":"page","link":"https:\/\/www.bu.edu\/odbl\/xray-imaging\/","title":{"rendered":"X-Ray Imaging"},"content":{"rendered":"<div class=\"bu-slideshow-container micro-ct-imaging autoplay\" id=\"bu-slideshow-container-1\" data-slideshow-name=\"micro-ct-imaging\" data-slideshow-delay=\"5000\" style=\"width: auto; \"><div class='slideshow-loader active'><div class='loader-animation'><\/div><p>loading slideshow...<\/p><\/div><div class=\"bu-slideshow-slides\"><ul class=\"bu-slideshow transition-slide\" id=\"bu-slideshow-1\"><li id=\"bu-slideshow-1_0\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-right\"><img src=\"\/odbl\/files\/2015\/03\/Figure1Aiii_bigger.png\" alt=\"\" \/><\/div><\/li><li id=\"bu-slideshow-1_1\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-right\"><img src=\"\/odbl\/files\/2015\/03\/Figure4_bigger.png\" alt=\"\" \/><\/div><\/li><li id=\"bu-slideshow-1_2\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-right\"><img src=\"\/odbl\/files\/2015\/03\/Fish_bigger.png\" alt=\"\" \/><\/div><\/li><li id=\"bu-slideshow-1_3\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-right\"><img src=\"\/odbl\/files\/2015\/03\/Fractureanalysis_bigger.png\" alt=\"\" \/><\/div><\/li><li id=\"bu-slideshow-1_4\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-right\"><img src=\"\/odbl\/files\/2015\/03\/GrwothPlateInjuryThickness_bigger.png\" alt=\"\" \/><\/div><\/li><li id=\"bu-slideshow-1_5\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-right\"><img src=\"\/odbl\/files\/2015\/03\/Menidia_Menidia_dor_skull_bigger.png\" alt=\"\" \/><\/div><\/li><li id=\"bu-slideshow-1_6\" class=\"slide \"><div class=\"bu-slide-container slide-caption-bottom-right\"><img src=\"\/odbl\/files\/2015\/03\/Mouse-Lung_bigger.png\" alt=\"\" \/><\/div><\/li><\/ul><\/div><div class=\"bu-slideshow-arrows\" id=\"bu-slideshow-1_arrows\"><a class=\"bu-slideshow-arrow-left\" href=\"#\"><\/a><a class=\"bu-slideshow-arrow-right\" href=\"#\"><\/a><\/div><\/div>\n<p><!--Need 1.5 spacing for all text--><br \/>\nMicro-computed tomography (\u03bcCT) is a three-dimensional, X-ray-based imaging modality that can image tissues, organs and whole organisms as well as nonorganic structures with a spatial resolution as high as 6-10 \u03bcm. \u03bcCT systems provide rapid, quantitative, high-resolution and three-dimensional assessment of both microstructure and density.\u00a0 \u03bcCT is nondestructive and can scan ex-vivo samples as large as 75 cubic centimeters\u00a0in several hours.<\/p>\n<p>X-ray microscopy (XRM) is a nearly identical imaging modality that combines X-ray imaging with microscope technology to enhance the spatial resolution to 0.7\u00a0<span> \u03bcm. \u00a0This unique set-up allows for ex-vivo and nonorganic samples of almost any size or shape to be imaged.<\/span><\/p>\n<p>The Micro-Computed Tomography Imaging Core Facility at BU has one \u03bcCT scanner and one X-ray microscope. The <span>\u03bcCT<\/span> scanner is a Scanco \u03bcCT40 system which is density calibrated on a weekly basis to keep our scans accurate. The XRM is the Zeiss Xradia Versa 520. We have multiple software options that allow for the identification of sub-regions for image segmentation, registration, and quantitative analysis. \u00a0Analyses can be performed on three-dimensional regions of interest to quantify porosity, thickness, and other features of the microstructure. Additionally, \u00a0two-dimensional regions of interest can be analyzed to quantify bone area, bone area fraction, cross-section area, and moment of inertia. We have the ability to render and export images in a variety of file formats.<\/p>\n<p>The systems are available for use regardless of affiliation with Boston University.\u00a0The cost per scan roughly scales with the amount of image data that are generated as well technician consultation, and optional analyses performed.\u00a0 Prospective users should contact the lab via the <a href=\"https:\/\/www.bu.edu\/odbl\/imaging-contact\/\" title=\"Imaging contact\">imaging\u00a0contact form<\/a>.<\/p>\n<p><!--Need caption for image--><br \/>\n<img loading=\"lazy\" src=\"\/odbl\/files\/2015\/08\/FX_Callus_Test.gif\" alt=\"FX_Callus_Test\" width=\"236\" height=\"300\" class=\"alignleft wp-image-1028 size-medium\" \/><\/p>\n<p><img loading=\"lazy\" src=\"\/odbl\/files\/2015\/08\/Bone-Rotation.gif\" alt=\"Bone-Rotation\" width=\"228\" height=\"300\" class=\"wp-image-1001 size-medium\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Micro-computed tomography (\u03bcCT) is a three-dimensional, X-ray-based imaging modality that can image tissues, organs and whole organisms as well as nonorganic structures with a spatial resolution as high as 6-10 \u03bcm. \u03bcCT systems provide rapid, quantitative, high-resolution and three-dimensional assessment of both microstructure and density.\u00a0 \u03bcCT is nondestructive and can scan ex-vivo samples as large [&hellip;]<\/p>\n","protected":false},"author":22170,"featured_media":0,"parent":0,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/odbl\/wp-json\/wp\/v2\/pages\/1395"}],"collection":[{"href":"https:\/\/www.bu.edu\/odbl\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bu.edu\/odbl\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/odbl\/wp-json\/wp\/v2\/users\/22170"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/odbl\/wp-json\/wp\/v2\/comments?post=1395"}],"version-history":[{"count":4,"href":"https:\/\/www.bu.edu\/odbl\/wp-json\/wp\/v2\/pages\/1395\/revisions"}],"predecessor-version":[{"id":1475,"href":"https:\/\/www.bu.edu\/odbl\/wp-json\/wp\/v2\/pages\/1395\/revisions\/1475"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/odbl\/wp-json\/wp\/v2\/media?parent=1395"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}