{"id":95,"date":"2011-02-03T13:41:10","date_gmt":"2011-02-03T18:41:10","guid":{"rendered":"https:\/\/www.bu.edu\/nf-kb\/?page_id=95"},"modified":"2013-01-31T16:58:53","modified_gmt":"2013-01-31T21:58:53","slug":"table-3","status":"publish","type":"page","link":"https:\/\/www.bu.edu\/nf-kb\/table-3\/","title":{"rendered":"Table 3"},"content":{"rendered":"

Miscellaneous inhibitors to NF-kB<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Inhibitor Molecule<\/strong><\/td>\nEffect or point of inhibition<\/strong><\/td>\nReferences<\/strong><\/td>\n<\/tr>\n
Azithromycin<\/td>\nInhibited expression of CD40 and CD86<\/td>\nIwamoto<\/a> et al, 2011<\/td>\n<\/tr>\n
Conophylline (Ervatamia microphylla)<\/td>\nDown regulated TNF-Receptors<\/td>\nGohda<\/a> et al, 2003<\/td>\n<\/tr>\n
MOL 294 (small molecule)<\/td>\nRedox regulated activation of NF-kB<\/td>\nHenderson<\/a> et al, 2002<\/td>\n<\/tr>\n
PEDF (pigment epithelium derived factor)<\/td>\nROS generation<\/td>\nYamagishi<\/a> et al, 2004<\/td>\n<\/tr>\n
Perrilyl alcohol<\/td>\nCalcium pathway<\/td>\nBerchtold <\/a>et al, 2005<\/td>\n<\/tr>\n
MAST205<\/td>\nTRAF6 binding<\/td>\nXiong<\/a> et al, 2004<\/td>\n<\/tr>\n
Rhein<\/td>\nMEKK activation of NF-kB<\/td>\nMartin<\/a> et al, 2003′ Domagala<\/a> et al, 2006<\/td>\n<\/tr>\n
15-deoxy-prostaglandin J(2)<\/td>\nPPARg activation of NF-kB<\/td>\nBoyault<\/a> et al, 2004<\/td>\n<\/tr>\n
Palmitoylethanolamide<\/td>\nPPARg activation of NF-kB<\/td>\nGenovese<\/a> et al, 2008<\/td>\n<\/tr>\n
NSC697923 (small molecule)<\/td>\nubiquitin-conjugating enzyme Ubc13-Uev1A<\/td>\nPulvino<\/a> et al, 2012<\/td>\n<\/tr>\n
Acute alcohol binge<\/td>\nBcl-3 upregulation<\/td>\nBala<\/a> et al, 2012<\/td>\n<\/tr>\n
Antrodia camphorata extract<\/td>\nIkBa upregulation<\/td>\nHsu <\/a>et al, 2005<\/td>\n<\/tr>\n
apigenin (4′,5,7-trihydroxyflavone)<\/td>\nIkBa upregulation<\/td>\nShukla<\/a> & Gupta, 2004<\/td>\n<\/tr>\n
Aresenic trioxide<\/td>\nIkBa upregulation<\/td>\nZhou<\/a> et al, 2006<\/td>\n<\/tr>\n
beta-amyloid protein<\/td>\nIkBa upregulation<\/td>\nBales<\/a> et al, 1998<\/td>\n<\/tr>\n
Chromium Picolinate\/ Histidinate<\/td>\nIkBa upregulation<\/td>\nSahin<\/a> et al, 2012<\/td>\n<\/tr>\n
Huang-lian-jie-du-tang<\/td>\nIkBa upregulation<\/td>\nHsu<\/a> et al,2008<\/td>\n<\/tr>\n
human breast milk<\/td>\nIkBa upregulation<\/td>\nMinekawa<\/a> et al, 2004<\/td>\n<\/tr>\n
Fruit Essential oil\u00a0 (from Cinnamomum insularimontanum)<\/td>\nIkBa upregulation; IKK and NF-kB downregulation<\/td>\nLin<\/a> et al, 2008<\/td>\n<\/tr>\n
FOXO3<\/td>\nIKK-\u03b2 downregulation<\/td>\nLuron<\/a> et al, 2012<\/td>\n<\/tr>\n
Surfactant protein A (SP-A)<\/td>\nIkBa upregulation<\/td>\nWu<\/a> et al, 2004<\/td>\n<\/tr>\n
DQ 65-79 (aa 65-79 of the alpha helix of the alpha-chain of the class II HLA molecule DQA03011)<\/td>\nIkBa upregulation and IKK inhibition<\/td>\nJiang<\/a> et al, 2002<\/td>\n<\/tr>\n
Cysteamine<\/td>\nIkBa upregulation and RelA donsregulation<\/td>\nOzaki<\/a> et al, 2007<\/td>\n<\/tr>\n
C5a<\/td>\nIkBa upregulation<\/td>\nRiedemann<\/a> et al, 2003<\/td>\n<\/tr>\n
Down Syndrome candidate region 1 protein<\/td>\nIkBa upregulation<\/td>\nKim<\/a> et al, 2006<\/td>\n<\/tr>\n
Glucocorticoids (dexamethasone, prednisone, methylprednisolone)<\/td>\nIkBa upregulation<\/td>\nAuphan<\/a> et al, 1995; Brostjan<\/a> et al, 1996; Ray<\/a> & Prefontaine, 1994; Scheinman<\/a> et al, 1995; Fong<\/a> et al, 2007<\/td>\n<\/tr>\n
IL-10<\/td>\nIkBa upregulation\/DNA binding<\/td>\nEhrlich<\/a> et al, 1998; Lentsch<\/a> et al, 1997; Shames<\/a> et al, 1998; Voboril<\/a> & Weberova-Voborilova, 2007<\/td>\n<\/tr>\n
IL-13<\/td>\nIkBa upregulation<\/td>\nEhrlich<\/a> et al, 1998; Lentsch<\/a> et al, 1997; Manna<\/a> & Aggarwal, 1998<\/td>\n<\/tr>\n
IL-11<\/td>\nIKKa; IkBa,IkBb upregulation<\/td>\nTrepicchio<\/a> & Dorner, 1998; Lgssiar<\/a> et al, 2004<\/td>\n<\/tr>\n
Mycoepoxydiene<\/td>\nIkBa upregulation<\/td>\nWang<\/a> et al, 2012<\/td>\n<\/tr>\n
alpha-pinene<\/td>\nIkBa upregulation<\/td>\nZhou<\/a> et al, 2004<\/td>\n<\/tr>\n
NEF (HIV-1)<\/td>\nIkBa upregulation<\/td>\nQiao<\/a> et al, 2006<\/td>\n<\/tr>\n
Ometin<\/td>\nIkBa upregulation<\/td>\nZhong<\/a> et al, 2012<\/td>\n<\/tr>\n
R-etodolac<\/td>\nIkBa upregulation<\/td>\nNeri<\/a> et al, 2006<\/td>\n<\/tr>\n
SR141716<\/td>\nIkBa upregulation<\/td>\nMalfitano<\/a> et al, 2007<\/td>\n<\/tr>\n
Vitamin D<\/td>\nIkBa upregulation<\/td>\nCohen-Lahav<\/a> et al, 2006<\/td>\n<\/tr>\n
Fox1j<\/td>\nIkBb upregulation<\/td>\nLin<\/a> et al, 2004<\/td>\n<\/tr>\n
NSP1 (rotavirus)<\/td>\nIkBa stabilizzation<\/td>\nSherry<\/a> et al, 2009<\/td>\n<\/tr>\n
Dioxin<\/td>\nRelA nuclear transport<\/td>\nRuby<\/a> et al, 2002<\/td>\n<\/tr>\n
Agastache rugosa leaf extract<\/td>\nNuclear translocation<\/td>\nOh<\/a> et al, 2005<\/a><\/td>\n<\/tr>\n
Alginic acid<\/td>\nNuclear translocation<\/td>\nJeong<\/a> et al, 2006<\/a><\/td>\n<\/tr>\n
Allopurinol<\/td>\nNuclear translocation<\/td>\nAldaba-Muruato<\/a> et al, 2011<\/td>\n<\/tr>\n
Apilimod<\/td>\nNuclear translocation<\/td>\nBillich<\/a>, 2007<\/a><\/td>\n<\/tr>\n
Astragaloside IV<\/td>\nNuclear translocation<\/td>\nZhang et al, 2003<\/a><\/td>\n<\/tr>\n
Atorvastatin<\/td>\nNuclear translocation<\/td>\nHaloui et al, 2003<\/a><\/td>\n<\/tr>\n
Azacitidine<\/td>\nNuclear translocation<\/td>\nKhong<\/a> et al, 2008<\/a><\/td>\n<\/tr>\n
Biaryl-based chalcones<\/td>\nNuclear translocation<\/td>\nZuo<\/a> et al, 2012<\/td>\n<\/tr>\n
Biophytum sensitivum<\/td>\nNuclear translocation<\/td>\nGuruvayoorappan<\/a> & Kuttan, 2008<\/a><\/td>\n<\/tr>\n
Blue honeysuckle extract<\/td>\nNuclear translocation<\/td>\nJin<\/a> et al, 2006<\/a><\/td>\n<\/tr>\n
BMD (N(1)-Benzyl-4-methylbenzene-1,2-diamine)<\/td>\nNuclear translocation<\/td>\nShin<\/a> et al, 2005<\/a><\/td>\n<\/tr>\n
Buthus martensi Karsch extract<\/td>\nNuclear translocation<\/td>\nKim et al, 2005<\/a><\/td>\n<\/tr>\n
Canine Distemper Virus<\/td>\nNuclear translocation<\/td>\nFriess et al, 2005<\/a><\/td>\n<\/tr>\n
Carbaryl<\/td>\nNuclear translocation<\/td>\nShimomura-Shimizu <\/strong>et al, 2005<\/a><\/td>\n<\/tr>\n
Captopril<\/td>\nNuclear translocation<\/td>\nHe<\/a> et al, 2007<\/td>\n<\/tr>\n
Carnostic acid<\/td>\nNuclear translocation<\/td>\nYu<\/a> et al, 2008<\/td>\n<\/tr>\n
Celastrol<\/td>\nNuclear translocation<\/td>\nPinna et al, 2004<\/a><\/td>\n<\/tr>\n
alpha-chaconine<\/td>\nNuclear translocation<\/td>\nShih<\/a> et al, 2007<\/a><\/td>\n<\/tr>\n
Chiisanoside<\/td>\nRelA Nuclear translocation<\/td>\nWon<\/a> et al, 2005<\/a><\/td>\n<\/tr>\n
CHS 828<\/td>\nNuclear translocation<\/td>\nHassan<\/a> et al, 2006<\/a><\/td>\n<\/tr>\n
Corilagin<\/td>\nNuclear translocation<\/td>\nZhao<\/a> et al, 2008<\/a><\/td>\n<\/tr>\n
CP-1158<\/td>\nNuclear translocation<\/td>\nKim<\/a> et al, 2006<\/a><\/td>\n<\/tr>\n
Dehydroxymethylepoxyquinomicin (DHMEQ)<\/td>\nNuclear translocation<\/td>\nChaicharoenpong<\/a> et al, 2002; Katsman<\/a> et al, 2007; Valera<\/a> et al 2012<\/td>\n<\/tr>\n
15-deoxyspergualin<\/td>\nNuclear translocation<\/td>\nHutchings et al, 2003<\/a><\/td>\n<\/tr>\n
Dipyridamole<\/td>\nNuclear translocation<\/td>\nWeyrich<\/a> et al, 2005<\/a><\/td>\n<\/tr>\n
Disulfiram<\/td>\nNuclear translocation<\/td>\nWang et al, 2003<\/a><\/td>\n<\/tr>\n
Diltiazem<\/td>\nNuclear translocation; induced translocation of p50 dimers<\/td>\nSevera<\/a> et al, 2005<\/a><\/td>\n<\/tr>\n
ERB-041<\/td>\nNuclear translocation<\/td>\nXiu-Li<\/a> et al, 2009<\/a><\/td>\n<\/tr>\n
Eriobotrya japonica triterpene acids<\/td>\nRelA nuclear translocation<\/td>\nHuang<\/a> et al, 2007<\/a><\/td>\n<\/tr>\n
Eriocalyxin B<\/td>\nNuclear translocation\/DNA binding<\/td>\nWang<\/a> et al, 2006<\/a>; Leung<\/a> et al, 2006<\/td>\n<\/tr>\n
Estrogen enhanced transcript<\/td>\nNuclear translocation<\/td>\nJin et al, 2003<\/a><\/td>\n<\/tr>\n
Eutigoside C<\/td>\nNuclear translocation<\/td>\nLee<\/a> et al, 2008<\/a><\/td>\n<\/tr>\n
FAK-related nonkinase<\/td>\nNuclear translocation<\/td>\nQin<\/a> & Liu, 2006<\/a><\/td>\n<\/tr>\n
Florfenicol<\/td>\nNuclear translocation<\/td>\nZhang<\/a> et al, 2008<\/a><\/td>\n<\/tr>\n
beta-funaltrexamine<\/td>\nNuclear translocation<\/td>\nDavis<\/a> et al, 2007<\/td>\n<\/tr>\n
Gangliosides<\/td>\nNuclear translocation<\/td>\nCaldwell<\/a> et al, 2003<\/td>\n<\/tr>\n
Glucorticoid-induced leucine zipper protein (GILZ)<\/td>\nNuclear translocation<\/td>\nRiccardi<\/a> et al, 2001<\/td>\n<\/tr>\n
Gymnocladus chinensis Baillon saponin<\/td>\nNuclear translocation<\/td>\nMa<\/a> et al, 2007<\/td>\n<\/tr>\n
Harpagophytum procumbens (Devil’s Claw) extracts<\/td>\nNuclear translocation<\/td>\nKaszkin<\/a> et al, 2004<\/td>\n<\/tr>\n
HDAC inhibitors sodium valproate, MS-275<\/td>\nRelB nuclear translocation; DNA binding<\/td>\nNencioni<\/a> et al, 2007; Rao<\/a> et al, 2007<\/td>\n<\/tr>\n
Heat shock protein 72<\/td>\nNuclear translocation<\/td>\nMeldrum<\/a> et al, 2003<\/td>\n<\/tr>\n
Hirsutenone<\/td>\nNuclear translocation<\/td>\nKim<\/a> et al, 2005<\/td>\n<\/tr>\n
Huanglian Jiedu concocotion (geniposide, baicalin, berberine)<\/td>\nNuclear translocation<\/td>\nYuan<\/a> et al, 2008<\/td>\n<\/tr>\n
Indole-3-carbinol<\/td>\nNuclear translocation<\/td>\nRahman<\/a> & Sarkar, 2005<\/td>\n<\/tr>\n
JM34 (benzamide derivative)<\/td>\nNuclear translocation<\/td>\nCarbonnelle et al, 2005<\/td>\n<\/tr>\n
JSH-23 (4-Methyl- -(3-phenyl-propyl)-benzene-1,2-diamine<\/td>\nNuclear translocation<\/td>\nShin<\/a> et al, 2004<\/td>\n<\/tr>\n
KIOM-79 (combined plant extracts)<\/td>\nNuclear translocation<\/td>\nJeon<\/a> et al, 2006<\/td>\n<\/tr>\n
KL-1156 (6-Hydroxy-7-methoxychroman-2-carboxylic acid phenylamide)<\/td>\nNuclear translocation<\/td>\nKim<\/a> et al, 2004; Kwak<\/a> et al, 2007<\/td>\n<\/tr>\n
Leptomycin B (LMB)<\/td>\nNuclear translocation<\/td>\nRodriguez<\/a> et al, 1999<\/td>\n<\/tr>\n
Levamisole<\/td>\nNuclear translocation<\/td>\nLiu<\/a> et al, 2004<\/td>\n<\/tr>\n
Lidamycin<\/td>\nNuclear translocation<\/td>\nChen<\/a> et al, 2007<\/td>\n<\/tr>\n
Lycopus lucidus Turcz<\/td>\nNuclear translocation<\/td>\nLee<\/a> et al, 2007<\/td>\n<\/tr>\n
Magnolia ovovata extract<\/td>\nNuclear translocation<\/td>\nTanaka<\/a> et al, 2007<\/td>\n<\/tr>\n
MEB (2-(4-morpholynl) ethyl butyrate hydrochloride)<\/td>\nNuclear translocation<\/td>\nSoderberg<\/a> et al, 2004<\/td>\n<\/tr>\n
Methimazole<\/td>\nNuclear translocation<\/td>\nCrescioli<\/a> et al, 2007<\/td>\n<\/tr>\n
MNF (IkB-like Myxoma virus)<\/td>\nNuclear translocation<\/td>\nCamus-Bouclainville<\/a> et al, 2004<\/td>\n<\/tr>\n
Montelukast<\/td>\nNuclear translocation; p65 HAT acitvity<\/td>\nWu<\/a> et al, 2006; Tahan<\/a> et al, 2008<\/td>\n<\/tr>\n
NLS Cell permeable peptides (SN50)<\/td>\nNuclear translocation<\/td>\nLin<\/a> et al, 1995<\/td>\n<\/tr>\n
NSA9 (prothrombin fragment)<\/td>\nNuclear translocation<\/td>\nKim<\/a> et al, 2008<\/td>\n<\/tr>\n
2′,8″-biapigenin<\/td>\nRelA nuclear translocation<\/td>\nWoo<\/a> et al, 2006<\/td>\n<\/tr>\n
Divaricate saposhnikovia root<\/td>\nRelA nuclear translocation<\/td>\nGe<\/a> et al, 2007<\/td>\n<\/tr>\n
Fineleaf schizonepeta herb<\/td>\nRelA nuclear translocation<\/td>\nGe<\/a> et al, 2007<\/td>\n<\/tr>\n
Glimperide<\/td>\nRelA nuclear translocation<\/td>\nJojima<\/a> et al, 2008<\/td>\n<\/tr>\n
Nucling<\/td>\nRelA nuclear translocation<\/td>\nLiu<\/a> et al, 2004<\/td>\n<\/tr>\n
o,o’-bismyristoyl thiamine disulfide (BMT)<\/td>\nNuclear translocation<\/td>\nShoji<\/a> et al, 1998<\/td>\n<\/tr>\n
Oregonin<\/td>\nRelA nuclear translocation<\/td>\nLee<\/a> et al, 2005<\/td>\n<\/tr>\n
\u03b3-Oryzanol (\u03b3-ORZ)<\/td>\nNuclear translocation<\/td>\nSakai <\/a>et al, 2012<\/td>\n<\/tr>\n
Fermented Oyaksungisan (OY)<\/td>\nNuclear translocation<\/td>\nOh<\/a> et al, 2012<\/td>\n<\/tr>\n
1,2,3,4,6-penta-O-galloyl-beta-d-glucose<\/td>\nRelA nuclear translocation<\/td>\nKang<\/a> et al, 2005<\/td>\n<\/tr>\n
Pergolide<\/td>\nNuclear translocation<\/td>\nUberti et al, 2004<\/td>\n<\/tr>\n
Platycodi radix extract<\/td>\nRelA nuclear translocation<\/td>\nLee<\/a> et al, 2004<\/td>\n<\/tr>\n
Phallacidin<\/td>\nNuclear translocation<\/td>\nPapakonstanti<\/a> & Strounaras, 2004<\/td>\n<\/tr>\n
Pimecrolimus<\/td>\nNuclear translocation<\/td>\nBuchau<\/a> et al, 2008<\/td>\n<\/tr>\n
Piperine<\/td>\nNuclear translocation<\/td>\nPradeep<\/a> & Kuttan, 2004<\/td>\n<\/tr>\n
Pitavastatin<\/td>\nNuclear translocation<\/td>\nWang<\/a> et al, 2006<\/td>\n<\/tr>\n
PN-50<\/td>\nNuclear translocation<\/td>\nLetoha<\/a> et al, 2005<\/td>\n<\/tr>\n
POP2<\/td>\nNuclear translocation<\/td>\nBedoya<\/a> et al, 2007<\/td>\n<\/tr>\n
Pravastatin<\/td>\nNuclear translocation<\/td>\nGu<\/a> et al, 2007<\/td>\n<\/tr>\n
Probiotics<\/td>\nRelA nuclear translocation<\/td>\nBai<\/a> et al, 2004<\/td>\n<\/tr>\n
Propofol<\/td>\nNuclear translocation<\/td>\nJawan<\/a> et al, 2008; He<\/a> et al, 2008<\/td>\n<\/tr>\n
RelA peptides (P1 and P6)<\/td>\nNuclear translocation<\/td>\nTakada<\/a> et al, 2004<\/td>\n<\/tr>\n
Retinoic acid receptor-related orphan receptor-alpha<\/td>\nNuclear translocation<\/td>\nMigita<\/a> et al, 2004<\/td>\n<\/tr>\n
Rhubarb aqueous extract<\/td>\nRelA nuclear translocation<\/td>\nMoon<\/a> et al, 2005; Liu<\/a> et al, 2008<\/td>\n<\/tr>\n
Rolipram<\/td>\nNuclear translocation<\/td>\nSanchez<\/a> et al, 2005; Ikezoe<\/a> et al, 2004; Herve<\/a> et al, 2008<\/td>\n<\/tr>\n
Salvia miltiorrhoza Bunge extract<\/td>\nNuclear translocation<\/td>\nDing<\/a> et al, 2005<\/td>\n<\/tr>\n
SC236 (a selective COX-2 inhibitor)<\/td>\nNuclear translocation<\/td>\nWong<\/a> et al, 2003<\/td>\n<\/tr>\n
Selenomethionine<\/td>\nNuclear translocation<\/td>\nCherukuri<\/a> et al, 2005<\/td>\n<\/tr>\n
Sorafenib<\/td>\nNuclear translocation<\/td>\nEcheverria<\/a> et al, 2009<\/td>\n<\/tr>\n
Cornuside<\/td>\nRelA Nuclear translocation<\/td>\nKang<\/a> et al, 2007<\/td>\n<\/tr>\n
ShenQi compound recipe<\/td>\nRelA Nuclear translocation<\/td>\nZhang<\/a> et al, 2006<\/td>\n<\/tr>\n
Sophorae radix extract<\/td>\nNuclear translocation<\/td>\nKwon<\/a> et al, 2004<\/td>\n<\/tr>\n
Sopoongsan<\/td>\nNuclear translocation<\/td>\nNa<\/a> et al, 2005<\/td>\n<\/tr>\n
Sphondin (furanocoumarin derivative from Heracleum laciniatum)<\/td>\nNuclear translocation<\/td>\nYang<\/a> et al, 2002<\/td>\n<\/tr>\n
Src homology protein (SHP)-1<\/td>\nNuclear translocation<\/td>\nWang<\/a> et al, 2012<\/td>\n<\/tr>\n
TAT-SR-IkBa; MTS-SR-IkBa<\/td>\nNuclear translocation<\/td>\nBlackwell <\/a>et al, 2004; Mora<\/a> et al, 2005<\/td>\n<\/tr>\n
Thymulin<\/td>\nNuclear translocation<\/td>\nDardenne<\/a> et al, 2006<\/td>\n<\/tr>\n
Tongxinluo Supermicro Powder<\/td>\nNuclear translocation<\/td>\nWu<\/a> et al, 2007; Bu<\/a> et al, 2008<\/td>\n<\/tr>\n
Vaccinia virus (VACV) strain Western Reserve protein C4<\/td>\nNuclear translocation<\/td>\nEmber <\/a>et al, 2012<\/td>\n<\/tr>\n
violaxanthin<\/td>\nRelA nuclear translocation<\/td>\nSoontornchaiboon<\/a> et al, 2012<\/td>\n<\/tr>\n
Volatile anesthetic treatment<\/td>\nNuclear translocation<\/td>\nLee<\/a> et al, 2004<\/td>\n<\/tr>\n
White currant<\/td>\nNuclear translocation<\/td>\nRajakangas<\/a> et al, 2008<\/td>\n<\/tr>\n
Younggaechulgam-tang<\/td>\nNuclear translocation<\/td>\nShin<\/a> et al, 2004<\/td>\n<\/tr>\n
ZUD protein<\/td>\nActivation of NF-kB; binds p105\/RelA<\/td>\nZhang<\/a> et al, 2004<\/td>\n<\/tr>\n
ZAS3 protein<\/td>\nRelA nuclear translocation; DNA competition<\/td>\nHong<\/a> et al, 2003<\/td>\n<\/tr>\n
Clarithromycin<\/td>\nnuclear expression<\/td>\nIchiyama<\/a> et al, 2001<\/td>\n<\/tr>\n
Fluvastatin<\/td>\nnuclear expression<\/td>\nAzuma<\/a> et al, 2004<\/td>\n<\/tr>\n
Leflunomide<\/td>\nRelA nuclear expression<\/td>\nYao<\/a> et al, 2004<\/td>\n<\/tr>\n
RASSF1A gene overexpression<\/td>\nRelA nuclear expression<\/td>\nDeng<\/a> et al, 2005<\/td>\n<\/tr>\n
VGX-1027<\/td>\nRelA nuclear expression<\/td>\nMangano<\/a> et al, 2008<\/td>\n<\/tr>\n
oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OXPAPC)<\/td>\nRelA expression<\/td>\nLi<\/a> et al, 2004<\/td>\n<\/tr>\n
3C protease (Poliovirus)<\/td>\nRelA expression (cleavage)<\/td>\nNeznanov<\/a> et al, 2005<\/td>\n<\/tr>\n
5F (from Pteri syeminpinnata L)<\/td>\nRelA expression<\/td>\nHe<\/a> et al, 2005<\/td>\n<\/tr>\n
AT514 (serratamolide)<\/td>\nRelA expression<\/td>\nEscobar-Diaz<\/a> et al, 2005<\/td>\n<\/tr>\n
Icariin<\/td>\nRelA expression<\/td>\nXu <\/a>et al, 2011<\/td>\n<\/tr>\n
Sorbus commixta cortex (methanol extract)<\/td>\nRelA expression<\/td>\nSohn<\/a> et al, 2005<\/td>\n<\/tr>\n
Astragalus membranaceus polysaccharide<\/td>\nNF-kB expression<\/td>\nLi<\/a> et al, 2007<\/td>\n<\/tr>\n
Azithromycin<\/td>\nNF-kB expression<\/td>\nZhang<\/a> et al, 2007<\/td>\n<\/tr>\n
Cantharidin<\/td>\nNF-kB expression<\/td>\nHe<\/a> et al, 2005<\/td>\n<\/tr>\n
Cornus officinalis extract<\/td>\nNF-kB expression<\/td>\nLi<\/a> et al, 2005<\/td>\n<\/tr>\n
Dan-shao-hua-xian<\/td>\nNF-kB expression<\/td>\nWang<\/a> & Cheng, 2008<\/td>\n<\/tr>\n
Gamboic acid<\/td>\nNF-kB expression<\/td>\nWang<\/a> et al, 2008<\/td>\n<\/tr>\n
Glycine<\/td>\nNF-kB expression<\/td>\nLaschke<\/a> et al, 2007<\/td>\n<\/tr>\n
Glycyrrhizic acid<\/td>\nNF-kB expression<\/td>\nAfnan<\/a> et al, 2012<\/td>\n<\/tr>\n
Korean mistletoe lectin<\/td>\nNF-kB expression<\/td>\nKhil<\/a> et al, 2007<\/td>\n<\/tr>\n
Lycium seed oil<\/td>\nNF-kB expression<\/td>\nJiang<\/a> et al, 2007<\/td>\n<\/tr>\n
Meiduoluomi<\/td>\nNF-kB expression<\/td>\nZhang<\/a> et al, 2008<\/td>\n<\/tr>\n
Neomycin<\/td>\nNF-kB expression<\/td>\nGarcia-Trapero<\/a> et al, 2004<\/td>\n<\/tr>\n
omapatrilat, enalapril, CGS 25462<\/td>\nNF-kB expression<\/td>\nPu<\/a> et al, 2005<\/td>\n<\/tr>\n
Onconase (Ranpirnase)<\/td>\nNF-kB expression<\/td>\nTsai<\/a> et al, 2004<\/td>\n<\/tr>\n
Paeoniflorin<\/td>\nNF-kB expression<\/td>\nLiu <\/a>et al, 2006<\/td>\n<\/tr>\n
Pouterin<\/td>\nRelA expression<\/td>\nBoleti<\/a> et al, 2008<\/td>\n<\/tr>\n
Rapamycin<\/td>\nNF-kB expression<\/td>\nLawrence<\/a> et al, 2004<\/td>\n<\/tr>\n
Sargassum hemiphyllum methanol extract<\/td>\nNF-kB expression<\/td>\nNa<\/a> et al, 2005<\/td>\n<\/tr>\n
Shenfu<\/td>\nNF-kB expression<\/td>\nZhang<\/a> et al, 2005; Wang<\/a> et al, 2008<\/td>\n<\/tr>\n
Tripterygium polyglycosides<\/td>\nNF-kB expression<\/td>\nZhou<\/a> et al, 2005<\/td>\n<\/tr>\n
Triflusal<\/td>\nnuclear expression<\/td>\nAcarin<\/a> et al, 2000<\/td>\n<\/tr>\n
Verbascoside<\/td>\nnuclear expression<\/td>\nPaola<\/a> et al, 2011<\/td>\n<\/tr>\n
Zoledronic acid<\/td>\nRelB, c-Rel expression<\/td>\nBringmann<\/a> et al, 2007; Wypij<\/a> et al, 2008<\/td>\n<\/tr>\n
Chlamydiae CT441 protease<\/td>\nCleaves RelA<\/td>\nLad<\/a> et al, 2007, 2007a<\/a><\/td>\n<\/tr>\n
HSCO (hepatoma protein)<\/td>\nAccelerates RelA nuclear export<\/td>\nHigashitsuji<\/a> et al, 2002<\/td>\n<\/tr>\n
Andrographolide<\/td>\nCovlalent adduct with Cys-62 of p50<\/td>\nXia<\/a> et al, 2004; Wang<\/a> et al, 2007<\/td>\n<\/tr>\n
Selencotyanates<\/td>\nCovlalent adduct with Cys-62 of p50<\/td>\nChen<\/a> et al, 2007<\/td>\n<\/tr>\n
Bee venom (melittin)<\/td>\nDNA binding by binding to p50<\/td>\nPark<\/a> et al, 2004; Moon<\/a> et al, 2007<\/td>\n<\/tr>\n
Ethyl pyruvate<\/td>\nDNA binding by RelA thru Cys-38<\/td>\nHan<\/a> et al, 2004<\/td>\n<\/tr>\n
Abies georgei extracts<\/td>\nDNA binding<\/td>\nYang<\/a> et al, 2008<\/td>\n<\/tr>\n
25-acetylcimigenol xylpoyranoside (from Black cohosh)<\/td>\nDNA binding<\/td>\nQiu<\/a> et al, 2007<\/td>\n<\/tr>\n
1′-acetoxychavicol acetate<\/td>\nDNA binding<\/td>\nIto<\/a> et al, 2005<\/td>\n<\/tr>\n
2-acetylaminofluorene<\/td>\nDNA binding<\/td>\nKang<\/a> et al, 2004; Jeon<\/a> et al, 1999<\/td>\n<\/tr>\n
Actinodaphine (from Cinnamomum insularimontanum)<\/td>\nDNA binding<\/td>\nHsieh<\/a> et al, 2004<\/td>\n<\/tr>\n
Adiponectin<\/td>\nDNA binding<\/td>\nAjuwon<\/a> & Spurlock, 2004; Wu<\/a> et al, 2007<\/td>\n<\/tr>\n
ADP ribosylation inhibitors (nicotinamide, 3-aminobenzamide)<\/td>\nDNA binding<\/td>\nLe Page<\/a> et al, 1998<\/td>\n<\/tr>\n
AIM2 (Absent In Melanoma protein) overexpression<\/td>\nDNA binding<\/td>\nChen<\/a> et al, 2006<\/td>\n<\/tr>\n
Albaconol<\/td>\nDNA bindng<\/td>\nLiu<\/a> et al, 2008<\/td>\n<\/tr>\n
Moderate alcohol intake<\/td>\nDNA binding<\/td>\nMandrekar<\/a> et al, 2006<\/td>\n<\/tr>\n
7-amino-4-methylcoumarin<\/td>\nDNA binding<\/td>\nKurokawa<\/a> et al, 2003<\/td>\n<\/tr>\n
Amrinone<\/td>\nDNA binding<\/td>\nChanani<\/a> et al, 2002<\/td>\n<\/tr>\n
Angelicae Gigantis Radix extract<\/td>\nDNA binding<\/td>\nKil<\/a> et al, 2008<\/td>\n<\/tr>\n
Angiopoietin-1<\/td>\nDNA binding<\/td>\nJeon<\/a> et al, 2003<\/td>\n<\/tr>\n
Anthocyanins (soybean)<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2006; Karlsen<\/a> et al, 2007<\/td>\n<\/tr>\n
Anti-Neu antibody + paclitaxel<\/td>\nDNA binding<\/td>\nYin<\/a> et al, 2007<\/td>\n<\/tr>\n
(S)-armepavine<\/td>\nDNA binding<\/td>\nLiu<\/a> et al, 2007<\/td>\n<\/tr>\n
Arnica montana extract (sequiterpene lactones)<\/td>\nDNA binding<\/td>\nKos<\/a> et al, 2005<\/td>\n<\/tr>\n
Artemisinin<\/td>\nDNA binding<\/td>\nAldieri<\/a> et al, 2003; Wang<\/a> et al, 2006<\/td>\n<\/tr>\n
Artepillin C<\/td>\nDNA binding<\/td>\nPaulino<\/a> et al, 2008<\/td>\n<\/tr>\n
Artesunate<\/td>\nDNA binding<\/td>\nLi<\/a> et al, 2008<\/td>\n<\/tr>\n
Arzanol<\/td>\nDNA binding<\/td>\nAppendino<\/a> et al, 2007<\/td>\n<\/tr>\n
Atrial Natriuretic Peptide (ANP)<\/td>\nDNA binding; IkBa upregulation<\/td>\nGerbes<\/a> et al, 1998; Kiemer<\/a> et al, 2002<\/td>\n<\/tr>\n
Atrovastat (HMG-CoA reductase inhibitor)<\/td>\nDNA binding<\/td>\nBustos<\/a> et al, 1998; Hernandez-Presa<\/a> et al, 1998<\/td>\n<\/tr>\n
Avocado-soybean unsaponifiables<\/td>\nDNA binding<\/td>\nGabay<\/a> et al, 2007<\/td>\n<\/tr>\n
AvrA protein (Salmonella)<\/td>\nDNA binding<\/td>\nCollier-Hyams<\/a> et al, 2002<\/td>\n<\/tr>\n
Baicalein (5,6,7-trihydroxyflavone)<\/td>\nDNA binding<\/td>\nSuk<\/a> et al, 2003<\/td>\n<\/tr>\n
Bambara groundnut (Vignea subterranean)<\/td>\nDNA binding<\/td>\nNa<\/a> et al, 2004<\/td>\n<\/tr>\n
Benfotiamine (thiamine derivative)<\/td>\nDNA binding<\/td>\nHammes<\/a> et al, 2003<\/td>\n<\/tr>\n
beta-catenin<\/td>\nDNA binding<\/td>\nDeng<\/a> et al, 2002<\/td>\n<\/tr>\n
beta-lapachone (a 1,2-naphthoquinone)<\/td>\nDNA binding; IKKb<\/td>\nTzeng<\/a> et al, 2003; Sumi<\/a> & Kumagai, 2007<\/td>\n<\/tr>\n
Biliverdin<\/td>\nDNA binding<\/td>\nYamashita<\/a> et al, 2004<\/td>\n<\/tr>\n
Bisphenol A<\/td>\nDNA binding<\/td>\nKim<\/a> & Jeong, 2003<\/td>\n<\/tr>\n
Bitter groud<\/td>\nDNA binding<\/td>\nKobori<\/a> et al, 2008<\/td>\n<\/tr>\n
Bovine serum albumin<\/td>\nDNA binding<\/td>\nZhang<\/a> & Frei, 2002<\/td>\n<\/tr>\n
Brazilian green propolis<\/td>\nDNA binding<\/td>\nBae<\/a> et al, 2005; Paulino<\/a> et al, 2006<\/td>\n<\/tr>\n
Bromelain<\/td>\nDNA binding; proteolysis of TNF, IL-1<\/td>\nHou<\/a> et al, 2006; Huang<\/a> et al, 2008; Chobotova<\/a> et al, 2010<\/td>\n<\/tr>\n
Calcium\/calmodulin-dependent kinase kinase (CaMKK) (and increased intracellular calcium by ionomycin, UTP and thapsigargin)<\/td>\nDNA binding<\/td>\nChen<\/a> et al, 2002<\/td>\n<\/tr>\n
Calcitriol (1a,25-dihydroxyvitamin D3)<\/td>\nDNA binding<\/td>\nHarant<\/a> et al, 1998; Chung<\/a> et al, 2007<\/td>\n<\/tr>\n
Campthothecin<\/td>\nDNA binding<\/td>\nHentze<\/a> et al, 2004<\/td>\n<\/tr>\n
Cancer bush (Sutherlandia frutescens)<\/td>\nDNA binding<\/td>\nNa<\/a> et al, 2004<\/td>\n<\/tr>\n
Candesartan<\/td>\nDNA binding<\/td>\nYu<\/a> et al, 2007; 2007a<\/a><\/td>\n<\/tr>\n
Cannabidiol<\/td>\nDNA binding<\/td>\nEsposito<\/a> et al, 2006<\/td>\n<\/tr>\n
Caprofen<\/td>\nDNA binding<\/td>\nBryant<\/a> et al, 2003<\/td>\n<\/tr>\n
Capsiate<\/td>\nDNA binding<\/td>\nSancho<\/a> et al, 2002<\/td>\n<\/tr>\n
Carbocisteine<\/td>\nDNA binding<\/td>\nYasuda<\/a> et al, 2006<\/td>\n<\/tr>\n
Catalposide (stem bark)<\/td>\nDNA binding<\/td>\nOh<\/a> et al, 2002<\/td>\n<\/tr>\n
Cat’s claw bark (Uncaria tomentosa; Rubiaceae); Maca<\/td>\nDNA binding<\/td>\nAguilar<\/a> et al, 2002; Valerio<\/a> & Gonzales, 2005<\/td>\n<\/tr>\n
CD43 overexpression<\/td>\nDNA binding (RelA)<\/td>\nLaos<\/a> et al, 2004<\/td>\n<\/tr>\n
CDX2<\/td>\nDNA binding<\/td>\nMutoh<\/a> et al, 2007<\/td>\n<\/tr>\n
Celecoxib and germcitabine<\/td>\nDNA binding; nuclear translocation<\/td>\nEl-Rayes<\/a> et al, 2004; Funakashi-Tago<\/a> et al, 2008<\/td>\n<\/tr>\n
Changtai granule<\/td>\nDNA binding<\/td>\nLiu<\/a> et al, 2007<\/td>\n<\/tr>\n
Cheongyeolsaseuptang<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2005<\/td>\n<\/tr>\n
Chitosan<\/td>\nDNA binding<\/td>\nSeo<\/a> et al, 2003; Chen<\/a> et la, 2008<\/td>\n<\/tr>\n
Chitooligosaccharides<\/td>\nDNA binding<\/td>\nLin<\/a> et al, 2006<\/td>\n<\/tr>\n
Cinnamaldehyde, 2-methoxycinnamaldehyde, 2-hydroxycinnamaldehyde<\/td>\nDNA binding\/IKK<\/td>\nReddy<\/a> et al, 2004; Lee<\/a> et al, 2005; Kim<\/a> et al, 2007; Liao<\/a> et al, 2008<\/td>\n<\/tr>\n
Chicory root (guaianolide 8-deoxylactucin)<\/td>\nDNA binding<\/td>\nCavin<\/a> et al, 2005<\/td>\n<\/tr>\n
Chlorophyllin<\/td>\nDNA binding<\/td>\nYun<\/a> et al, 2005<\/td>\n<\/tr>\n
Chondrotin sulfate from Styela clava tunic<\/td>\nDNA binding<\/td>\nXu<\/a> et al, 2008<\/td>\n<\/tr>\n
Chondrotin sulfate proteoglycan degradation product<\/td>\nDNA binding; nuclear translocation<\/td>\nRolls<\/a> et al, 2006; Jomphe<\/a> et al, 2007<\/td>\n<\/tr>\n
Clarithromycin<\/td>\nDNA binding<\/td>\nMiyanohara<\/a> et al, 2000<\/td>\n<\/tr>\n
Cloricromene<\/td>\nDNA binding<\/td>\nIanaro<\/a> et al, 2004<\/td>\n<\/tr>\n
CO-releasing molecules (CORM-2)<\/td>\nDNA binding<\/td>\nSun<\/a> et al, 2007<\/td>\n<\/tr>\n
Cocaethylene<\/td>\nDNA binding<\/td>\nTacker<\/a> et al, 2006<\/td>\n<\/tr>\n
Commerical peritoneal dialysis solution<\/td>\nDNA binding<\/td>\nDouvdevani<\/a> et al, 1995<\/td>\n<\/tr>\n
Compounds K and Rh(2) (from Panax ginseng)<\/td>\nDNA binding\/IKK<\/td>\nPark<\/a> et al, 2005; Choi<\/a> et al, 2007; Chang<\/a> et al, 2007<\/td>\n<\/tr>\n
Cortex cinnamomi extract<\/td>\nDNA binding<\/td>\nKwon<\/a> et al, 2006<\/td>\n<\/tr>\n
CP Compound (6-Hydroxy-7-methoxychroman-2-carboxylic acid phenylamide)<\/td>\nDNA binding<\/td>\nRak Min<\/a> et al, 2005<\/td>\n<\/tr>\n
Cryptotanshinone<\/td>\nDNA binding<\/td>\nZhou<\/a> et al, 2005; Jeon<\/a> et al, 2008<\/td>\n<\/tr>\n
Cyanoguanidine CHS 828<\/td>\nDNA binding<\/td>\nJohanson<\/a> et al, 2006<\/td>\n<\/tr>\n
Cytochalasin D<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2003<\/td>\n<\/tr>\n
DA-9201 (from black rice)<\/td>\nDNA binding<\/td>\nLee<\/a> et al, 2005<\/td>\n<\/tr>\n
Danshenshu (esp Salvionic acid B)<\/td>\nDNA binding<\/td>\nJiang <\/a>et al, 2001; Luo<\/a> et al, 2008<\/td>\n<\/tr>\n
(kB site) Decoy oligonucleotides<\/td>\nDNA binding<\/td>\nKupatt<\/a> et al, 2002; Morishita<\/a> et al, 1997<\/td>\n<\/tr>\n
Deoxypodophyllotoxin<\/td>\nDNA binding<\/td>\nJin<\/a> et al, 2008<\/td>\n<\/tr>\n
Diallyl trisulfide<\/td>\nDNA binding<\/td>\nZhu<\/a> et al, 2007<\/td>\n<\/tr>\n
Diamide<\/td>\nDNA binding<\/td>\nToledano<\/a> & Leonard, 1991<\/td>\n<\/tr>\n
Diarylheptanoid 7-(4′-hydroxy-3′-methoxyphenyl)-1-phenylhept-4-en-3-one<\/td>\nDNA binding<\/td>\nYadav<\/a> et al, 2003<\/td>\n<\/tr>\n
alpha-difluoromethylornithine (polyamine depletion)<\/td>\nDNA binding<\/td>\nFacchini<\/a> et al, 2005<\/td>\n<\/tr>\n
S-diclofenac (2-[92,6-dichlorphenyl-amino]benzeneacetic acid 4-[3H-1,2,dithiol-3-thione-5-y) pheny ester)<\/td>\nDNA binding<\/td>\nLi<\/a> et al, 2007<\/td>\n<\/tr>\n
7,7′-dihydroxy bursehernin<\/td>\nDNA binding<\/td>\nPokharel<\/a> et al, 2006<\/td>\n<\/tr>\n
3,3′-diindolymethane<\/td>\nDNA binding<\/td>\nKong<\/a> et al, 2007; Rahman<\/a> et al, 2007<\/td>\n<\/tr>\n
DIM\/13C<\/td>\nDNA binding<\/td>\nLi<\/a> et al, 2005<\/td>\n<\/tr>\n
Dimemorfan<\/td>\nDNA binding<\/td>\nWang<\/a> et al, 2008<\/td>\n<\/tr>\n
Diterpenoids from Isodon rubescens or Liverwort Jungermannia<\/td>\nDNA binding<\/td>\nLeung<\/a> et al, 2005; Kondoh<\/a> et al, 2005<\/td>\n<\/tr>\n
Docetaxel (Taxotere)<\/td>\nDNA binding<\/td>\nBanerjee<\/a> et al, 2007<\/td>\n<\/tr>\n
Dohongsamultang<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2007<\/td>\n<\/tr>\n
DTD (4,10-dichloropyrido[5,6:4,5]thieno[3,2- d’:3,2- d]-1, 2, 3-ditriazine)<\/td>\nDNA binding<\/td>\nRioja<\/a> et al, 2002<\/td>\n<\/tr>\n
Duchesnea indica extract<\/td>\nDNA binding<\/td>\nZhao<\/a> et al,\u00a0 2008<\/td>\n<\/tr>\n
E1B (Adenovirus)<\/td>\nDNA binding<\/td>\nLimbourg<\/a> et al, 1996<\/td>\n<\/tr>\n
E3330 (quinone derivative)<\/td>\nDNA binding<\/td>\nHiramoto<\/a> et al, 1998; Kimura<\/a> et al, 1997<\/td>\n<\/tr>\n
Ellagic acid<\/td>\nDNA binding<\/td>\nEdderkaoui<\/a> et al, 2008<\/td>\n<\/tr>\n
Emodin<\/td>\nDNA binding<\/td>\nGuo<\/a> et al, 2012<\/td>\n<\/tr>\n
ent-kaurane diterpenoids (Croton tonkinensis leaves; Isodon excisus)<\/td>\nDNA binding<\/td>\nGiang<\/a> et al, 2003; Hong<\/a> et al, 2007<\/td>\n<\/tr>\n
Epinastine hydrochloride<\/td>\nDNA binding<\/td>\nKanai<\/a> et al, 2006<\/td>\n<\/tr>\n
(+)-Episesamin<\/td>\nDNA binding<\/td>\nFreise<\/a> et al, 2011<\/td>\n<\/tr>\n
Epoxyquinol A (fungal metabolite)<\/td>\nDNA binding<\/td>\nLi<\/a> et al, 2002<\/td>\n<\/tr>\n
Ergosterol peroxide, ergosterol, cervisterol (from Canthaellus cibarius)<\/td>\nDNA binding<\/td>\nKobori<\/a> et al, 2006; Kim<\/a> et al, 2008<\/td>\n<\/tr>\n
Erythromycin<\/td>\nDNA binding\/transactivation<\/td>\nRen<\/a> et al, 2004; Desaki<\/a> et al, 2004<\/td>\n<\/tr>\n
Evans Blue<\/td>\nDNA binding<\/td>\nSharma<\/a> et al, 2004<\/td>\n<\/tr>\n
Evodiamine<\/td>\nDNA binding<\/td>\nChoi<\/a> et al, 2006<\/td>\n<\/tr>\n
Fenoldopam<\/td>\nDNA binding<\/td>\nAravindan<\/a> et al, 2006<\/td>\n<\/tr>\n
Fexofenadine hydrochloride<\/td>\nDNA binding<\/td>\nAsano<\/a> et al, 2004<\/td>\n<\/tr>\n
Fentanyl<\/td>\nDNA binding<\/td>\nLiu<\/a> et al, 2006<\/td>\n<\/tr>\n
Fibrates<\/td>\nDNA binding<\/td>\nHirano<\/a> et al, 2002<\/td>\n<\/tr>\n
Fish oil feeding<\/td>\nDNA binding<\/td>\nFan<\/a> et al, 2004; Ma<\/a> et al, 2007<\/td>\n<\/tr>\n
FK778<\/td>\nDNA binding<\/td>\nZeyda<\/a> et al, 2005<\/td>\n<\/tr>\n
FLN29 overexpression<\/td>\nDNA binding<\/td>\nMashima<\/a> et al, 2005<\/td>\n<\/tr>\n
FLICE-Like Inhibitory Protein (FLIP)<\/td>\nDNA binding<\/td>\nBannerman<\/a> et al, 2004<\/td>\n<\/tr>\n
Flunixin meglumine<\/td>\nDNA binding<\/td>\nBryant<\/a> et al, 2003<\/td>\n<\/tr>\n
Flurbiprofen<\/td>\nDNA binding<\/td>\nFratelli<\/a> et al, 2003<\/td>\n<\/tr>\n
Flutamide<\/td>\nDNA binding<\/td>\nShimizu<\/a> et al, 2007<\/td>\n<\/tr>\n
fMLP (bacterial peptide)<\/td>\nDNA binding<\/td>\nEswarappa<\/a> et al, 2008<\/td>\n<\/tr>\n
Folimycin<\/td>\nDNA binding<\/td>\nPark<\/a> et al, 2004<\/td>\n<\/tr>\n
Fomes fomentarius methanol extracts<\/td>\nDNA binding<\/td>\nPark<\/a> et al, 2004<\/td>\n<\/tr>\n
Fucoidan<\/td>\nDNA binding<\/td>\nHaneji<\/a> et al, 2005<\/td>\n<\/tr>\n
G-120 (Ulmus davidiana Nakai glycoprotein)<\/td>\nDNA binding; IkB increases<\/td>\nSon<\/a> et al, 2004; Lee<\/a> et al, 2005<\/td>\n<\/tr>\n
Gallic acid<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2005<\/td>\n<\/tr>\n
Ganoderic acid<\/td>\nDNA binding<\/td>\nJiang<\/a> et al, 2008<\/td>\n<\/tr>\n
Ganoderma lucidum (fungal dried spores or fruting body)<\/td>\nDNA binding<\/td>\nSliva<\/a> et al, 2002<\/td>\n<\/tr>\n
Garcinol (fruit rind of Garcinia spp)<\/td>\nDNA binding<\/td>\nHong<\/a> et al, 2005<\/td>\n<\/tr>\n
Gax (homeobox protein)<\/td>\nDNA binding<\/td>\nPatel<\/a> et al, 2005<\/td>\n<\/tr>\n
Geranylgeraniol<\/td>\nDNA binding<\/td>\nEspindola<\/a> et al, 2005<\/td>\n<\/tr>\n
Geranylgeranylacetone<\/td>\nDNA binding<\/td>\nHayakawa<\/a> et al, 2007<\/td>\n<\/tr>\n
Ghrelin<\/td>\nDNA binding<\/td>\nLi<\/a> et al, 2004<\/td>\n<\/tr>\n
Gigantol (Cymbidium georingii)<\/td>\nDNA binding<\/td>\nWon<\/a> et al, 2006<\/td>\n<\/tr>\n
Gingyo-san<\/td>\nDNA binding<\/td>\nYeh<\/a> et al, 2007<\/td>\n<\/tr>\n
Ginkgolide B<\/td>\nDNA binding<\/td>\nNie<\/a> et al, 2004<\/td>\n<\/tr>\n
Ginseng saponin 20-O-b-D-glucopyranosyl-20(S)-protopanaxadiol<\/td>\nDNA binding<\/td>\nChoo<\/a> et al, 2008<\/td>\n<\/tr>\n
Glycyrrhizin<\/td>\nDNA binding<\/td>\nWang<\/a> et al, 1998; Yuan<\/a> et al, 2006<\/td>\n<\/tr>\n
H4\/N5 (IkB-like proteins of Microplitis demolitor bracovirus)<\/td>\nDNA binding<\/td>\nThoetkiattikul<\/a> et al, 2005<\/td>\n<\/tr>\n
Halofuginone<\/td>\nDNA binding<\/td>\nLeiba<\/a> et al, 2006<\/td>\n<\/tr>\n
Heat (fever-like)<\/td>\nDNA binding<\/td>\nSalanova<\/a> et al, 2005<\/td>\n<\/tr>\n
Helenalin (sesquiterpene lactone)<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2005<\/td>\n<\/tr>\n
Hematein (plant compound)<\/td>\nDNA binding<\/td>\nOh<\/a> et al, 2001<\/td>\n<\/tr>\n
Heparin<\/td>\nDNA binding<\/td>\nLee<\/a> et al, 2007<\/td>\n<\/tr>\n
Herbal compound 861<\/td>\nDNA binding<\/td>\nYou<\/a> et al, 2001<\/td>\n<\/tr>\n
Hesperetin<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2006<\/td>\n<\/tr>\n
HIV-1 Resistance Factor<\/td>\nDNA binding<\/td>\nLesner<\/a> et al, 2005<\/td>\n<\/tr>\n
Hottuynia cordata Thunb extract<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2007<\/td>\n<\/tr>\n
Hyaluronan<\/td>\nDNA binding<\/td>\nYasuda<\/a> & Nakamura, 2007<\/td>\n<\/tr>\n
Hydroxyethyl starch<\/td>\nDNA binding<\/td>\nTian<\/a> et al, 2003; Feng<\/a> et al, 2006<\/td>\n<\/tr>\n
Hydroxyethylpuerarin<\/td>\nDNA binding\/Nucl Translocation<\/td>\nLou<\/a> et al, 2004; 2007<\/a>; Ding<\/a> et al, 2007<\/td>\n<\/tr>\n
Hypercapnic acidosis<\/td>\nDNA binding<\/td>\nChonghaile<\/a> et al, 2005<\/td>\n<\/tr>\n
Hypericin<\/td>\nDNA binding<\/td>\nBork<\/a> et al, 1999<\/td>\n<\/tr>\n
Hyperosmolarity<\/td>\nDNA binding<\/td>\nLang<\/a> et al, 2003<\/td>\n<\/tr>\n
Hypothermia<\/td>\nDNA binding<\/td>\nHassoun<\/a> et al, 2003<\/td>\n<\/tr>\n
Hydroquinone (HQ)<\/td>\nDNA binding<\/td>\nPyatt<\/a> et al, 1998<\/td>\n<\/tr>\n
ICP27 (HSV-1)<\/td>\nDNA binding<\/td>\nMelchjorsen<\/a> et al, 2006<\/td>\n<\/tr>\n
Interleukin 4 (IL-4)<\/td>\nDNA binding<\/td>\nManna<\/a> & Aggarwal, 1998; Voboril<\/a> & Weberova-Voborilova, 2007<\/td>\n<\/tr>\n
IkB-like protein A238L (encoded by ASFV)<\/td>\nDNA binding<\/td>\nPowell<\/a> et al, 1996; Revilla<\/a> et al, 1998<\/td>\n<\/tr>\n
Ilimaquinone<\/td>\nDNA binding<\/td>\nLu<\/a> et al, 1996<\/td>\n<\/tr>\n
Indoxam<\/td>\nDNA binding<\/td>\nSonaki<\/a> et al, 2008<\/td>\n<\/tr>\n
Insulin-like growth factor binding protein-3<\/td>\nDNA binding<\/td>\nWilliams<\/a> et al, 2006<\/td>\n<\/tr>\n
Irisilidone<\/td>\nDNA binding<\/td>\nPark<\/a> et al, 2006<\/td>\n<\/tr>\n
JNP3<\/td>\nDNA binding<\/td>\nYu<\/a> et al, 2012<\/td>\n<\/tr>\n
JSH-21 (N1-Benzyl-4-methylbenzene-1,2-diamine)<\/td>\nDNA binding<\/td>\nMin<\/a> et al, 2004<\/td>\n<\/tr>\n
Kamebakaurin<\/td>\nDNA binding<\/td>\nLee<\/a> et al, 2002<\/td>\n<\/tr>\n
Kaposi’s sarcoma-associated herpesvirus K1 protein<\/td>\nDNA binding<\/td>\nLee<\/a> et al, 2002<\/td>\n<\/tr>\n
Ketamine<\/td>\nDNA binding<\/td>\nSun<\/a> et al, 2004; Yu<\/a> et al, 2007<\/td>\n<\/tr>\n
KT-90 (morphine synthetic derivative)<\/td>\nDNA binding<\/td>\nSueoka<\/a> et al, 1998<\/td>\n<\/tr>\n
Lactobacillus fermentum phospholipid<\/td>\nDNA binding<\/td>\nFrick<\/a> et al, 2007<\/td>\n<\/tr>\n
Lichochalcone E<\/td>\nDNA binding<\/td>\nChang<\/a> et al, 2007<\/td>\n<\/tr>\n
Lignin<\/td>\nDNA bindin<\/td>\nMitsuhashi<\/a> et al, 2007<\/td>\n<\/tr>\n
Linoleic acid<\/td>\nDNA binding<\/td>\nZhao<\/a> et al, 2005; Cui<\/a> et al, 2006<\/td>\n<\/tr>\n
Lithospermi radix<\/td>\nDNA binding<\/td>\nChung<\/a> et al, 2005<\/td>\n<\/tr>\n
Lovastatin<\/td>\nDNA binding<\/td>\nSun<\/a> & Fernandes, 2003<\/td>\n<\/tr>\n
Lornoxicam<\/td>\nDNA binding<\/td>\nYin<\/a> et al, 2008<\/td>\n<\/tr>\n
Lucidenic acid<\/td>\nDNA bindng<\/td>\nWeng<\/a> et al, 2007<\/td>\n<\/tr>\n
Macrolide antibiotics<\/td>\nDNA binding<\/td>\nNguyen<\/a> et al, 2002<\/td>\n<\/tr>\n
Malloapelta B<\/td>\nDNA binding<\/td>\nVan Luu<\/a> et al, 2006<\/td>\n<\/tr>\n
Mediterranean plant extracts<\/td>\nDNA binding<\/td>\nStalinska<\/a> et al, 2005<\/td>\n<\/tr>\n
Mercaptopyrazine<\/td>\nDNA binding<\/td>\nLim<\/a> et al, 2004<\/td>\n<\/tr>\n
2-methoxyestradiol<\/td>\nDNA binding; <\/p>\n

Transactivation<\/td>\n

Shimada<\/a> et al, 2004; Takada<\/a> et al, 2004<\/td>\n<\/tr>\n
6-(Methylsulfinyl)hexyl isothiocyanate (Wasabi)<\/td>\nDNA binding; <\/p>\n

Transactivation<\/td>\n

Uto<\/a> et al, 2005<\/td>\n<\/tr>\n
Metals (chromium, cadmium, gold, lead, mercury, zinc, arsenic)<\/td>\nDNA binding\/IKK<\/td>\nShumilla<\/a> et al, 1998; Yang et al, 1995; Zuscik<\/a> et al, 2002; Momeny<\/a> et al, 2009<\/td>\n<\/tr>\n
Mevinolin, 5′-methylthioadenosine (MTA)<\/td>\nDNA binding<\/td>\nLaw<\/a> et al, 1992<\/td>\n<\/tr>\n
Methylglyoxal<\/td>\nDNA binding<\/td>\nLaga<\/a> et al,\u00a0 2007<\/td>\n<\/tr>\n
Mirtazapine<\/td>\nDNA binding<\/td>\nZhu<\/a> et al,\u00a0 2008<\/td>\n<\/tr>\n
Monomethylfumarate<\/td>\nDNA binding<\/td>\nLitjens<\/a> et al, 2004<\/td>\n<\/tr>\n
Morphine<\/td>\nDNA binding<\/td>\nLiu<\/a> et al, 2006; Lin<\/a> et al, 2007<\/td>\n<\/tr>\n
Moutan cortex<\/td>\nDNA binding<\/td>\nChung<\/a> et al, 2007; Kim<\/a> et al, 2007; Chun<\/a> et al, 2007<\/td>\n<\/tr>\n
Moxifloxacin<\/td>\nDNA binding<\/td>\nWerber<\/a> et al, 2005; Shalit<\/a> et al, 2005<\/td>\n<\/tr>\n
Myricetin<\/td>\nDNA binding<\/td>\nKang<\/a> et al, 2005; Lee<\/a> et al, 2007<\/td>\n<\/tr>\n
NDPP1 (CARD protein)<\/td>\nDNA binding<\/td>\nZhang<\/a> & Fu, 2002<\/td>\n<\/tr>\n
N-ethyl-maleimide (NEM)<\/td>\nDNA binding<\/td>\nToledano<\/a> & Leonard, 1991<\/td>\n<\/tr>\n
Naringen<\/td>\nDNA binding<\/td>\nKanno<\/a> et al, 2005<\/td>\n<\/tr>\n
Nicorandil<\/td>\nDNA binding<\/td>\nKatamura<\/a> et al, 2005<\/td>\n<\/tr>\n
Nicotine<\/td>\nDNA binding<\/td>\nSugano<\/a> et al, 1998<\/td>\n<\/tr>\n
Nifedipine<\/td>\nDNA binding<\/td>\nHoriuchi<\/a> et al, 2006; Tomita<\/a> et al, 2008; Aoki<\/a> et al, 2008<\/td>\n<\/tr>\n
Nitric oxide-donating aspirin<\/td>\nDNA binding<\/td>\nKashfi<\/a> & Rigas, 2005<\/td>\n<\/tr>\n
Nilvadipine<\/td>\nDNA binding<\/td>\nIwasaki<\/a> et al, 2005<\/td>\n<\/tr>\n
Nitrosoglutathione<\/td>\nDNA binding<\/td>\nKuo<\/a> et al, 2004; Khan<\/a> et al, 2005<\/td>\n<\/tr>\n
NS1 (Influenza A)<\/td>\nDNA binding<\/td>\nWang<\/a> et al, 2000<\/td>\n<\/tr>\n
NS3\/4A (Hepatitis C virus)<\/td>\nDNA binding<\/td>\nKarayiannis<\/a>, 2005<\/td>\n<\/tr>\n
Extracts of Ochna macrocalyx bark<\/td>\nDNA binding<\/td>\nTang<\/a> et al, 2003<\/td>\n<\/tr>\n
Leucine-rich effector proteins of Salmonella & Shigella (SspH1 and IpaH9.8)<\/td>\nDNA binding<\/td>\nHaraga<\/a> & Miller, 2003<\/td>\n<\/tr>\n
Oleic acid<\/td>\nDNA binding<\/td>\nCui<\/a> et al, 2006<\/td>\n<\/tr>\n
Mediterranean diet (virgin olive oil)<\/td>\nDNA binding<\/td>\nPerez-Martinez<\/a> et al, 2007; Brunelleschi<\/a> et al, 2007<\/td>\n<\/tr>\n
Melilotus suaveolens Ledeb extract<\/td>\nDNA binding<\/td>\nZhao<\/a> et al, 2007<\/td>\n<\/tr>\n
Omega-3 fatty acids<\/td>\nDNA binding<\/td>\nSethi<\/a>, 2002<\/td>\n<\/tr>\n
Orazipone<\/td>\nDNA binding<\/td>\nSareila<\/a> et al, 2007<\/td>\n<\/tr>\n
Oridonin (diterpenoid from Rabdosia rubescens)<\/td>\nDNA binding<\/td>\nIkezoe<\/a> et al, 2005<\/td>\n<\/tr>\n
p8<\/td>\nDNA binding<\/td>\nVasseur<\/a> et al, 2004<\/td>\n<\/tr>\n
1,2,3,4,6-penta-O-galloyl-beta-D-glucose<\/td>\nDNA binding<\/td>\nOh<\/a> et al, 2001<\/td>\n<\/tr>\n
p202a (interferon inducible protein)<\/td>\nDNA binding by p65 and p50\/p65; increases p50<\/td>\nMa<\/a> et al, 2003<\/td>\n<\/tr>\n
p21 (recombinant)<\/td>\nDNA binding<\/td>\nKhanna<\/a> et al, 2005<\/strong><\/td>\n<\/tr>\n
PC-SPES (8 herb mixture)<\/td>\nDNA binding<\/td>\nIkezoe<\/a> et al, 2003; 2006<\/a><\/td>\n<\/tr>\n
Panepoxydone<\/td>\nDNA binding<\/td>\nErkel<\/a> et al, 1996<\/td>\n<\/tr>\n
Peptide nucleic acid-DNA decoys<\/td>\nDNA binding<\/td>\nPenolazzi<\/a> et al, 2004<\/td>\n<\/tr>\n
Pentoxifylline (1-(5′-oxohexyl) 3,7-dimetylxanthine, PTX)<\/td>\nDNA binding<\/td>\nBiswas<\/a> et al, 1993; Wang <\/a>et al, 1997; Ji<\/a> et al, 2004<\/td>\n<\/tr>\n
Peptide YY<\/td>\nDNA binding<\/td>\nVona-Davis<\/a> et al, 2004<\/td>\n<\/tr>\n
Pepluanone<\/td>\nDNA binding<\/td>\nCorea<\/a> et al, 2005<\/td>\n<\/tr>\n
Perindopril<\/td>\nDNA binding<\/td>\nLi<\/a> et al, 2005<\/td>\n<\/tr>\n
Phellodendri cortex extract<\/td>\nDNA binding<\/td>\nPark<\/a> et al, 2007<\/td>\n<\/tr>\n
6(5H)-phenanthridinone and benzamide<\/td>\nDNA binding<\/td>\nChiarugi<\/a>, 2002<\/td>\n<\/tr>\n
Phyllanthus amarus extracts<\/td>\nDNA binding<\/td>\nKiemer<\/a> et al, 2003<\/td>\n<\/tr>\n
Phylligenin (lignan, Forsythia koreana)<\/td>\nDNA binding<\/td>\nLim<\/a> et al, 2008<\/td>\n<\/tr>\n
Phyllostachys nigra var. henonis (bamboo) extract<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2007<\/td>\n<\/tr>\n
PIAS1 (protein inhibitor of activatated STAT1)<\/td>\nRelA DNA binding<\/td>\nLiu<\/a> et al, 2005<\/td>\n<\/tr>\n
Pioglitazone (PPARgamma ligand)<\/td>\nDNA binding<\/td>\nTakagi<\/a> et al, 2002; Xu<\/a> et al, 2007; Xing<\/a> et al, 2007<\/td>\n<\/tr>\n
Pirfenidone<\/td>\nDNA binding<\/td>\nTsuchiya<\/a> et al, 2004; Nakanishi<\/a> et al, 2004<\/td>\n<\/tr>\n
Polyozellin<\/td>\nDNA binding<\/td>\nJin<\/a> et al, 2006<\/td>\n<\/tr>\n
Ponapensin<\/td>\nDNA binding<\/td>\nSalim et al, 2007<\/a><\/td>\n<\/tr>\n
Pregabalin; gabapentin<\/td>\nDNA binding<\/td>\nPark<\/a> et al, 2008<\/td>\n<\/tr>\n
Prenylbisabolane 3 (from Croton eluteria Bennett)<\/td>\nDNA binding<\/td>\nCampagnuoloe<\/a> et al, 2005<\/td>\n<\/tr>\n
Pro-opiomelanocortin<\/td>\nDNA binding<\/td>\nLiu<\/a> et al, 2005<\/td>\n<\/tr>\n
Procyandin B2<\/td>\nDNA binding<\/td>\nMackenzie<\/a> et al, 2008<\/td>\n<\/tr>\n
Prostaglandin E2<\/td>\nDNA binding and RelA nuclear translocation<\/td>\nMin<\/a> et al, 2002; Gomez<\/a> et al, 2005<\/td>\n<\/tr>\n
Protein-bound polysaccharide (PSK)<\/td>\nDNA binding<\/td>\nZhang<\/a> et al, 2003<\/td>\n<\/tr>\n
PYPAF1 protein<\/td>\nDNA binding<\/td>\nJeru<\/a> et al, 2006<\/td>\n<\/tr>\n
Pyridine N-oxide derivatives<\/td>\nDNA binding<\/td>\nStevens<\/a> et al, 2006<\/td>\n<\/tr>\n
Pyrithione<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 1999<\/td>\n<\/tr>\n
Pyrrole-imidazole polyamides<\/td>\nDNA binding<\/td>\nWurtz<\/a> et al, 2006<\/td>\n<\/tr>\n
Quinadril (ACE inhibitor)<\/td>\nDNA binding<\/td>\nBustos<\/a> et al, 1998; Hernandez-Presa<\/a> et al, 1998<\/td>\n<\/tr>\n
Quinic acid<\/td>\nDNA binding<\/td>\nAkesson<\/a> et al, 2005<\/td>\n<\/tr>\n
Raf Kinase Inhibitor Protein (RKIP)<\/td>\nDNA binding<\/td>\nKeller<\/a>, 2004<\/td>\n<\/tr>\n
Rapomycin<\/td>\nDNA binding<\/td>\nDichtl<\/a> et al, 2005<\/td>\n<\/tr>\n
Raloxifene<\/td>\nRelA DNA binding<\/td>\nOlivier<\/a> et al, 2006<\/td>\n<\/tr>\n
Raxofelast<\/td>\nDNA binding<\/td>\nAltavilla<\/a> et al, 2003<\/td>\n<\/tr>\n
Reactive oxygen species<\/td>\nDNA binding<\/td>\nYang<\/a> et al, 2007<\/td>\n<\/tr>\n
Rebamipide<\/td>\nDNA binding<\/td>\nHahm<\/a> et al, 2003<\/td>\n<\/tr>\n
Red\u00a0 and Siberian ginseng<\/td>\nDNA binding<\/td>\nPark<\/a> et al, 2007; Lin<\/a> et al, 2008<\/td>\n<\/tr>\n
Rhus verniciflua Stokes fruits 36 kDa glycoprotein\/ phenolic fraction<\/td>\nDNA binding<\/td>\nKo<\/a> et al, 2005; Jung<\/a> et al, 2006; Oh<\/a> et al, 2006<\/td>\n<\/tr>\n
Ribavirin<\/td>\nDNA binding<\/td>\nFiedler<\/a> et al, 1996<\/td>\n<\/tr>\n
Rifamides<\/td>\nDNA binding<\/td>\nPahlevan<\/a> et al, 2002<\/td>\n<\/tr>\n
Ritonavir<\/td>\nDNA binding<\/td>\nIkezoe<\/a> et al, 2004<\/td>\n<\/tr>\n
RNA aptamer to NF-kB<\/td>\nDNA binding<\/td>\nMi<\/a> et al, 2007; Wurster<\/a> et al, 2009<\/td>\n<\/tr>\n
Rosiglitazone<\/td>\nDNA binding<\/td>\nGruden<\/a> et al, 2005<\/td>\n<\/tr>\n
Roxithromycin<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2004<\/td>\n<\/tr>\n
Rungia pectinata (linn.) Nees extract<\/td>\nDNA binding<\/td>\nZhao<\/a> et al, 2008<\/td>\n<\/tr>\n
Sanggenon C<\/td>\nDNA binding<\/td>\nLi<\/a> et al, 2002<\/td>\n<\/tr>\n
Santonin diacetoxy acetal derivative<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2006<\/td>\n<\/tr>\n
Scapharca broughtonii factor<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2007<\/td>\n<\/tr>\n
Secretory leukoprotease inhibitor (SLPI)<\/td>\nDNA binding<\/td>\nJin<\/a> et al, 1997: Greene<\/a> et al, 2004; Taggart<\/a> et al, 2005<\/td>\n<\/tr>\n
Serotonin derivative (N-(p-coumaroyl) serotonin, SC)<\/td>\nDNA binding<\/td>\nKawashima<\/a> et al, 1998<\/td>\n<\/tr>\n
Sesamin (from sesame oil)<\/td>\nDNA binding<\/td>\nJeng<\/a> et al, 2005<\/td>\n<\/tr>\n
Shen-Fu<\/td>\nDNA binding<\/td>\nQian<\/a> et al, 2006<\/td>\n<\/tr>\n
Short chain fatty acids (sodium butyrate, sodium phenylbutyrate, sodium phenylacetate)<\/td>\nDNA binding<\/td>\nPark<\/a> et al, 2007; Debierre-Grockiego<\/a> et al, 2007; Kuefer<\/a> et al, 2007; Tedelind<\/a> et al, 2007<\/td>\n<\/tr>\n
Siah2<\/td>\nDNA binding<\/td>\nHabelhah<\/a> et al, 2002<\/td>\n<\/tr>\n
Silibinin<\/td>\nDNA binding<\/td>\nSchumann<\/a> et al, 2003<\/td>\n<\/tr>\n
Simvastatin<\/td>\nDNA binding\/IkB phosphorylation<\/td>\nLi<\/a> et al, 2002; Kalyanasundaram<\/a> et al, 2006; Lee<\/a> et al, 2007<\/td>\n<\/tr>\n
Sinomenine<\/td>\nDNA binding\/nuclear translocation<\/td>\nChen<\/a> et al, 2004; Zhao<\/a> et al, 2007<\/td>\n<\/tr>\n
SIRT1 Deacetylase overexpression<\/td>\nDNA binding<\/td>\nChen<\/a> et al, 2005<\/td>\n<\/tr>\n
Siva-1<\/td>\nDNA binding<\/td>\nGudi<\/a> et al, 2006<\/td>\n<\/tr>\n
SM-7368 (small molecule)<\/td>\nDNA binding<\/td>\nLee<\/a> et al, 2005<\/td>\n<\/tr>\n
Sodium tanshinone IIA sulfonate<\/td>\nDNA binding<\/td>\nXu<\/a> et al, 2008<\/td>\n<\/tr>\n
Solanum nigrum L. 150 kDa glycoprotein<\/td>\nDNA binding<\/td>\nHeo<\/a> et al, 2004; Lee<\/a> & Lim, 2006; Oh<\/a> & Lim, 2006<\/td>\n<\/tr>\n
SP100030<\/td>\nDNA binding<\/td>\nMoore-Carrasco<\/a> et al, 2007<\/td>\n<\/tr>\n
Styrax japonica terpenes and lignans<\/td>\nDNA binding<\/td>\nYun<\/a> et al, 2006<\/td>\n<\/tr>\n
Suberosin<\/td>\nDNA binding<\/td>\nChen<\/a> et al, 2006<\/td>\n<\/tr>\n
Sulfasalazine<\/td>\nDNA binding<\/td>\nEgan<\/a> & Sandborn, 1998<\/td>\n<\/tr>\n
SUN C8079<\/td>\nDNA binding<\/td>\nMatsumori<\/a> et al, 2004<\/td>\n<\/tr>\n
Surfactant protein A<\/td>\nDNA binding<\/td>\nAlcorn<\/a> & Wright, 2003<\/td>\n<\/tr>\n
Sword brake fern extract<\/td>\nDNA binding<\/td>\nWu<\/a> et al, 2003<\/td>\n<\/tr>\n
(+) Syringaresinal-di-O-beta-d-glucoside<\/td>\nDNA binding<\/td>\nYamazaki<\/a> et al, 2007<\/td>\n<\/tr>\n
T-614 (a methanesulfoanilide anti-arthritis inhibitor)<\/td>\nDNA binding<\/td>\nAikawa<\/a> et al, 2002<\/td>\n<\/tr>\n
Talosin A<\/td>\nDNA binding<\/td>\nHwang<\/a> et al, 2009<\/td>\n<\/tr>\n
Tanacetum larvatum extract<\/td>\nDNA binding<\/td>\nPetrovic<\/a> et al, 2003<\/td>\n<\/tr>\n
Tansinones (Salvia miltiorrhiza Bunge, Labiatae roots)<\/td>\nDNA binding<\/td>\nChoi<\/a> et al, 2004<\/td>\n<\/tr>\n
Taurine + niacine<\/td>\nDNA binding<\/td>\nGiri<\/a>, 2003; Kim <\/a>& Kim, 2005<\/td>\n<\/tr>\n
Temozolomide<\/td>\nDNA binding<\/td>\nYamini<\/a> et al, 2007<\/td>\n<\/tr>\n
Tetramethylpyrazine<\/td>\nDNA binding<\/td>\nCheng<\/a> et al, 2006<\/td>\n<\/tr>\n
Tobacoo smoke<\/td>\nDNA binding<\/td>\nZhong<\/a> et al, 2006<\/td>\n<\/tr>\n
Tom1 (target of Myb-1) overexpression<\/td>\nDNA binding<\/td>\nYamakami<\/a> & Yokosawa, 2004<\/td>\n<\/tr>\n
Thiazolidinedione MCC-555<\/td>\nDNA binding<\/td>\nKurebayashi<\/a> et al, 2005; Ohga<\/a> et al, 2006<\/td>\n<\/tr>\n
Trachelospermi caulis extract<\/td>\nDNA binding<\/td>\nLee<\/a> et al, 2007<\/td>\n<\/tr>\n
Transdominant p50<\/td>\nDNA binding<\/td>\nLogeat<\/a> et al, 1991<\/td>\n<\/tr>\n
Trichostatin A; 4-Me(2)N-BAVAH<\/td>\nRelA DNA binding<\/td>\nHu & Colburn<\/a>, 2005; Papeleu<\/a> et al, 2007<\/td>\n<\/tr>\n
Triclosan plus cetylpyridinium chloride<\/td>\nDNA binding<\/td>\nKim<\/a> et al, 2005<\/td>\n<\/tr>\n
Triptolide (PG490, extract of Chinese herb)<\/td>\nDNA binding\/transactivation<\/td>\nQiu<\/a> et al, 1999; Kim<\/a> et al, 2004; Yinjun<\/a> et al, 2005; Jang<\/a> et al, 2007; Chang<\/a> et al, 2007; He<\/a> et al, 2007; Liou<\/a> et al, 2008<\/td>\n<\/tr>\n
Tyrphostin AG-126<\/td>\nDNA binding<\/td>\nMoore<\/a> et al, 2003<\/td>\n<\/tr>\n
UNBS1450 01 (from C procera)<\/td>\nDNA binding<\/td>\nJuncker<\/a> et al, 2009<\/td>\n<\/tr>\n
Uranyl acetate<\/td>\nDNA binding<\/td>\nHartsock<\/a> et al, 2007<\/td>\n<\/tr>\n
Ursolic acid<\/td>\nDNA binding<\/td>\nHsu<\/a> et al, 2004<\/td>\n<\/tr>\n
Uteroglobin<\/td>\nDNA binding<\/td>\nMandal<\/a> et al, 2004<\/td>\n<\/tr>\n
V,C proteins (Sendai virus)<\/td>\nDNA binding<\/td>\nKomatsu<\/a> et al, 2004<\/td>\n<\/tr>\n
Vascular endothelial growth factor (VEGF)<\/td>\nDNA binding<\/td>\nOyama<\/a> et al, 1998; Gabrilovich<\/a> et al, 1998<\/td>\n<\/tr>\n
Verapamil<\/td>\nDNA binding<\/td>\nLi<\/a> et al, 2006<\/td>\n<\/tr>\n
Wei-Pi-Tang-Hab-Wu-Ling-San extract<\/td>\nDNA binding<\/td>\nJung<\/a> et al, 2007; Seok<\/a> et al, 2008<\/td>\n<\/tr>\n
Withaferin A<\/td>\nDNA binding; IKKb; proteasome<\/td>\nMohan<\/a> et al, 2004; Kaileh<\/a> et al, 2007; Yang<\/a> et al, 2007; Singh<\/a> et al, 2007<\/td>\n<\/tr>\n
Wogonin (5,7-dihydroxy-8-methoxyflavone)<\/td>\nDNA binding<\/td>\nLee<\/a> et al, 2003; Piao<\/a> et al, 2004;<\/td>\n<\/tr>\n
Xanthohumol (a hops prenylflavonoid)<\/td>\nDNA binding<\/td>\nColgate<\/a> et al, 2006<\/td>\n<\/tr>\n
Xanthorrhizol<\/td>\nDNA binding<\/td>\nChung<\/a> et al, 2007<\/td>\n<\/tr>\n
Xylitol<\/td>\nDNA binding<\/td>\nHan<\/a> et al, 2005<\/td>\n<\/tr>\n
Yan-gan-wan<\/td>\nDNA binding<\/td>\nYang<\/a> et al, 2005<\/td>\n<\/tr>\n
Yan Xin Qigong<\/td>\nDNA binding<\/td>\nYan<\/a> et al, 2007<\/td>\n<\/tr>\n
YC-1<\/td>\nDNA binding<\/td>\nLu<\/a> et al, 2007<\/td>\n<\/tr>\n
Yin-Chen-Hao<\/td>\nDNA binding<\/td>\nCai<\/a> et al, 2006<\/td>\n<\/tr>\n
Yucca schidigera extract<\/td>\nDNA binding<\/td>\nMarzocco<\/a> et al, 2004; Cheeke<\/a> et al, 2006<\/td>\n<\/tr>\n
Zapotin (from Caimiroa edulis)<\/td>\nDNA binding<\/td>\nMaiti<\/a> et al, 2007<\/td>\n<\/tr>\n
Overexpressed ZIP1<\/td>\nDNA binding<\/td>\nKhadeer<\/a> et al, 2005<\/td>\n<\/tr>\n
Zyflamend<\/td>\nDNA binding<\/td>\nSandur<\/a> et al, 2007<\/td>\n<\/tr>\n
Plant compound A (a phenyl aziridine precursor)<\/td>\nDNA binding and transactivation<\/td>\nDe Bosscher<\/a> et al, 2005<\/td>\n<\/tr>\n
L(pro) (Foot & Mouth Disease Virus)<\/td>\nRelA degradation<\/td>\nde Los Santos<\/a> et al, 2007<\/td>\n<\/tr>\n
8-acetoxy-5-hydroxyumbelliprenin (from Asafetida)<\/td>\nTransactivation<\/td>\nAppendino<\/a> et al, 2006<\/td>\n<\/tr>\n
agonist for the A(3) adenosine receptor<\/td>\nTransactivation<\/td>\nVarani<\/a> et al, 2012<\/td>\n<\/tr>\n
AMP-activated protein kinase<\/td>\nTransactivation<\/td>\nCacicedo<\/a> et al, 2004<\/td>\n<\/tr>\n
APC0576<\/td>\nTransactivation<\/td>\nYuzawa<\/a> et al, 2003<\/td>\n<\/tr>\n
Artemisia sylvatica sesquiterpene lactones<\/td>\nTransactivation (reporter assays)<\/td>\nJin<\/a> et al, 2004<\/td>\n<\/tr>\n
Artemisolide<\/td>\nTransactivation; IKKb<\/td>\nReddy<\/a> et al, 2006; Kim<\/a> et al, 2007<\/td>\n<\/tr>\n
Asteraceae sesquiterpene lactones (enhydrin, tetraludin A, repandins A, B, D, E)<\/td>\nTransactivation<\/td>\nMa<\/a> et al, 2006<\/td>\n<\/tr>\n
BSASM (plant extract mixture)<\/td>\nTransactivation (reporter assays)<\/td>\nLee<\/a> et al, 2005<\/td>\n<\/tr>\n
Bifodobacteria<\/td>\nTransactivation<\/td>\nRiedel<\/a> et al, 2006<\/td>\n<\/tr>\n
Breast cancer metastasis suppressor 1 (BRMS1)<\/td>\nTransactivation<\/td>\nSamant<\/a> et al, 2007<\/td>\n<\/tr>\n
Bupleurum fruticosum phenylpropanoids<\/td>\nTransactivation<\/td>\nBremner<\/a> et al, 2004<\/td>\n<\/tr>\n
Blueberry and berry mix (Optiberry)<\/td>\nTransactivation<\/td>\nAtalay<\/a> et al, 2003<\/td>\n<\/tr>\n
BZLF1 (EBV protein)<\/td>\nTransactivation<\/td>\nMorrison<\/a> et al, 2004<\/td>\n<\/tr>\n
ceramide-1-phosphate<\/td>\nTransactivation<\/td>\nHankins<\/a> et al, 2011<\/td>\n<\/tr>\n
Chromene derivatives<\/td>\nTransactivation<\/td>\nCheng<\/a> et al, 2003<\/td>\n<\/tr>\n
D609 (phosphatidylcholine-phospholipase C inhibitor)<\/td>\nTransactivation<\/td>\nBergmann<\/a> et al, 1998<\/td>\n<\/tr>\n
Dehydroevodiamine<\/td>\nTransactivation<\/td>\nNoh<\/a> et al, 2006<\/td>\n<\/tr>\n
4′-demethyl-6-methoxypodophyllotoxin (lignan of Linum tauricum Willd. ssp. tauricum)<\/td>\nTransactivation<\/td>\nVailev<\/a> et al, 2005<\/td>\n<\/tr>\n
5alpha-dihydrotestosterone<\/td>\nTransactivation<\/td>\nItoh<\/a> et al, 2007<\/td>\n<\/tr>\n
Ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl)) <\/p>\n

amino]-4-(trifluoromethyl)<\/p>\n

pyrimidine-5-carboxylate<\/td>\n

Transactivation<\/td>\nPalanki<\/a> et al, 2002<\/td>\n<\/tr>\n
Chemical library inhibitors<\/td>\nTransactivation<\/td>\nLee<\/a> et al, 2007<\/td>\n<\/tr>\n
CHFR<\/td>\nRelA Transactivation<\/td>\nKashima<\/a> et al, 2009<\/td>\n<\/tr>\n
Cycloprodigiosin hycrochloride<\/td>\nTransactivation<\/td>\nKamata<\/a> et al, 2001<\/td>\n<\/tr>\n
DC-81<\/td>\nTransactivation<\/td>\nHu<\/a> et al, 2008<\/td>\n<\/tr>\n
Dimethylfumarate (DMF)<\/td>\nNuclear translocation<\/td>\nLoewe<\/a> et al, 2002; Meili-Butz<\/a> et al, 2008<\/td>\n<\/tr>\n
E1A (Adenovirus)<\/td>\nTransactivation<\/td>\nCook<\/a> et al, 2002<\/td>\n<\/tr>\n
Eckol\/Dieckol (seaweed E stolonifera)<\/td>\nTransactivation<\/td>\nJoe<\/a> et al, 2006<\/td>\n<\/tr>\n
Ethanol<\/td>\nTransactivation<\/td>\nKlei<\/a> & Barchowsky, 2008<\/td>\n<\/tr>\n
FAD24<\/td>\nRelA transactivation<\/td>\nJohmura<\/a> et al, 2008<\/td>\n<\/tr>\n
Feijoa sellowiana Berg Fruit extract<\/td>\nTransactivation<\/td>\nRossi<\/a> et al, 2007<\/td>\n<\/tr>\n
Fructus Benincasae Recens extract<\/td>\nTransactivation<\/td>\nKwon<\/a> et al, 2003<\/td>\n<\/tr>\n
Gallotannins<\/td>\nTransactivation<\/td>\nLee<\/a> et al, 2007<\/td>\n<\/tr>\n
Glucocorticoids (dexametasone, prednisone, methylprednisolone)<\/td>\nTransactivation and increases IkBa levels<\/td>\nAuphan<\/a> et al, 1995; Brostjan<\/a> et al, 1996; Ray<\/a> & Prefontaine,1994; Scheinman<\/a> et al, 1995<\/td>\n<\/tr>\n
Glcodelin-A<\/td>\nTransactivation<\/td>\nTee<\/a> et al, 2008<\/td>\n<\/tr>\n
Gypenoside XLIX (from Gynostemma pentaphyllum)<\/td>\nTransactivation (PPAR-alpha-dependent)<\/td>\nHuang<\/a> et al, 2006<\/td>\n<\/tr>\n
Hesperidin<\/td>\nTransactivation<\/td>\nYeh<\/a> et al, 2007<\/td>\n<\/tr>\n
Heterocyclic ring-substituted pyrimidines<\/td>\nTransactivation<\/td>\nHa<\/a> et al, 2007<\/td>\n<\/tr>\n
Histidine<\/td>\nTransactivation<\/td>\nSon<\/a> et al, 2005<\/td>\n<\/tr>\n
HIV-1 protease inhibitors (nelfinavir, ritonavir, or saquinavir)<\/td>\nTransactivation<\/td>\nEquils<\/a> et al, 2004<\/td>\n<\/tr>\n
4-Hydroxykobusin<\/td>\nTransactivation<\/td>\nPokharel<\/a> et al, 2007<\/td>\n<\/tr>\n
ICT (3, 5, 7-Trihydroxy-4′-methoxy-8-(3-hydroxy-3- methylbutyl)-flavone)<\/td>\nTransactivation<\/td>\nWu<\/a> et al, 2011<\/td>\n<\/tr>\n
IE2p86 (CMV)<\/td>\nTransactivation<\/td>\nGealy<\/a> et al, 2007<\/td>\n<\/tr>\n
N-aminoimidazole derivatives (NR-818)<\/td>\nTransactivation<\/td>\nStevens<\/a> et al, 2007<\/td>\n<\/tr>\n
Kwei Ling Ko (Tortoise shell-Rhizome jelly)<\/td>\nTransactivation<\/td>\nYip<\/a> et al, 2005<\/td>\n<\/tr>\n
Ligusticum chuanxiong Hort root<\/td>\nTransactivation<\/td>\nLiu<\/a> et al, 2005<\/td>\n<\/tr>\n
Low gravity<\/td>\nTransactivation<\/td>\nBoonyaratanakornkit<\/a> et al, 2005<\/td>\n<\/tr>\n
Lys-Pro-Val tripeptide<\/td>\nTransactivation<\/td>\nDalmasso<\/a> et al, 2007<\/td>\n<\/tr>\n
LZAP<\/td>\nTransactivation<\/td>\nWang<\/a> et al, 2007<\/td>\n<\/tr>\n
Nobiletin<\/td>\nTransactivation\/DNA binding<\/td>\nMurakami<\/a> et al, 2005; Choi<\/a> et al, 2007<\/td>\n<\/tr>\n
NRF (NF-kB repression factor)<\/td>\nTransactivation<\/td>\nJianfeng <\/a>et al, 2004<\/td>\n<\/tr>\n
Paeonol (from Mountain Cortx)<\/td>\nTransactivation<\/td>\nIshiguro<\/a> et al, 2006;Tsai<\/a> et al, 2008<\/td>\n<\/tr>\n
Phenethylisothiocyanate<\/td>\nTransactivation<\/td>\nGerhauser<\/a> et al, 2003<\/td>\n<\/tr>\n
4-phenylcoumarins (from Marila pluricostata)<\/td>\nTransactivation<\/td>\nBedoya<\/a> et al, 2005<\/td>\n<\/tr>\n
Phomol<\/td>\nTransactivation<\/td>\nWeber<\/a> et al, 2004<\/td>\n<\/tr>\n
Pimpinella oils<\/td>\nTransactivation<\/td>\nTabanca<\/a> et al, 2007<\/td>\n<\/tr>\n
PIAS3<\/td>\nTransactivation<\/td>\nJang<\/a> et al, 2004<\/td>\n<\/tr>\n
Pranlukast<\/td>\nTransactivation<\/td>\nIchiyama<\/a> et al, 2003; Ishinaga<\/a> et al, 2004<\/td>\n<\/tr>\n
Psychosine<\/td>\nTransactivation<\/td>\nHaq<\/a> et al, 2003<\/td>\n<\/tr>\n
Pycnogenol<\/td>\nTransactivation<\/td>\nMatsumori<\/a> et al, 2007<\/td>\n<\/tr>\n
Quinazolines<\/td>\nTransactivation<\/td>\nTobe<\/a> et al, 2003<\/td>\n<\/tr>\n
Resveratrol<\/td>\nRelA nuclear localization and transactivation<\/td>\nManna<\/a> et al, 2000; Pendurthi<\/a> et al, 2002;; Kang<\/a> et al, 2009<\/td>\n<\/tr>\n
RO31-8220 (PKC inhibitor)<\/td>\nTransactivation<\/td>\nBergmann<\/a> et al, 1998<\/td>\n<\/tr>\n
Saucerneol D and saucerneol E<\/td>\nTransactivation<\/td>\nHwang<\/a> et al, 2003<\/td>\n<\/tr>\n
SB203580 (p38 MAPK inhibitor)<\/td>\nTransactivation<\/td>\nBergmann<\/a> et al, 1998<\/td>\n<\/tr>\n
SB216763 (GSK-3\u03b2 inhibitor)<\/td>\nTransactivation<\/td>\nDie<\/a> et al, 2012<\/td>\n<\/tr>\n
Selenium<\/td>\nTransactivation<\/td>\nChristensen<\/a> et al, 2007; Youn<\/a> et al, 2008<\/td>\n<\/tr>\n
SH protein (Mumps virus)<\/td>\nTransactivation<\/td>\nWilson<\/a> et al, 2006<\/td>\n<\/tr>\n
Silica-ceramic<\/td>\nTransactivation<\/td>\nHuang<\/a> et al, 2006<\/td>\n<\/tr>\n
Streptochlorin<\/td>\nTransactivation<\/td>\nChoi <\/a>et al, 2007<\/td>\n<\/tr>\n
Tranilast [N-(3,4-dimethoxycinnamoyl)anthranilic acid]<\/td>\nTransactivation<\/td>\nSpiecker<\/a> et al, 2002<\/td>\n<\/tr>\n
3,4,5-trimethoxy-4′-fluorochalcone<\/td>\nTransactivation<\/td>\nRojas<\/a> et al, 2003<\/td>\n<\/tr>\n
Uncaria tomentosum plant extract<\/td>\nTransactivation<\/td>\nAkesson<\/a> et al, 2003<\/td>\n<\/tr>\n
LY294,002<\/td>\nTransactivation<\/td>\nSizemore<\/a> et al, 1999<\/td>\n<\/tr>\n
Anatabine citrate<\/td>\nRelA phosphorylation &\u00a0 transactivation<\/td>\nParis<\/a> et al, 2011; 2013<\/a><\/td>\n<\/tr>\n
Mesalamine<\/td>\nRelA phosphorylation &\u00a0 transactivation<\/td>\nEgan<\/a> et al, 1999<\/td>\n<\/tr>\n
Mesuol<\/td>\nRelA phosphorylation &\u00a0 transactivation<\/td>\nMarquez <\/a>et al, 2005<\/td>\n<\/tr>\n
Multivalent liposomal antibodies (trastuzumab and rituximab)<\/td>\nRelA phosphorylation and transactivation<\/td>\nChiu<\/a> et al, 2007<\/td>\n<\/tr>\n
PTX-B (pertussis toxin binding protein)<\/td>\nRelA phosphorylation and transactivation<\/td>\nIordanskiy<\/a> et al, 2002<\/td>\n<\/tr>\n
Pyrolae herba extract<\/td>\nRelA phosphorylation and transactivation<\/td>\nLee<\/a> et al, 2007<\/td>\n<\/tr>\n
9-aminoacridine (9AA) derivatives (including the antimalaria drug quinacrine)<\/td>\nRelA phosphorylation and transactivation<\/td>\nGurova<\/a> et al, 2005<\/td>\n<\/tr>\n
SK-126<\/td>\nRelA phosphorylation<\/td>\nKang<\/a> et al, 2007<\/td>\n<\/tr>\n
Tetrandrine<\/td>\nRelA phosphorylation<\/td>\nHe<\/a> et al, 2011<\/td>\n<\/tr>\n
Adenosine and cyclic AMP<\/td>\nTransactivation<\/td>\nMajumdar<\/a> & Aggarwal, 2003; Minguet<\/a> et al, 2004<\/td>\n<\/tr>\n
17-allylamino-17-demethoxygeldanamycin<\/td>\nTransactivation<\/td>\nRakitina<\/a> et al, 2003<\/td>\n<\/tr>\n
5-Aminoisoquinolinone<\/td>\nTransactivation<\/td>\nWu<\/a> et al, 2012<\/td>\n<\/tr>\n
6-aminoquinazoline derivatives<\/td>\nTransactivation<\/td>\nTobe<\/a> et al, 2003<\/td>\n<\/tr>\n
Luteolin<\/td>\np65 Transactivation<\/td>\nKim<\/a> et al, 2003; Chen<\/a> et al, 2007<\/td>\n<\/tr>\n
Manassantins A and B<\/td>\np65 Transactivation<\/td>\nLee<\/a> et al, 2003; Son<\/a> et al, 2005<\/td>\n<\/tr>\n
MYBBP1a<\/td>\np65 Transactivation<\/td>\nOwen<\/a> et al, 2006<\/td>\n<\/tr>\n
Paromyxovirus SH gene products<\/td>\nTransactivation<\/td>\nWilson<\/a> et al, 2006<\/td>\n<\/tr>\n
Qingkailing and Shuanghuanglian (Chinese medicinal preparations)<\/td>\nTransactivation<\/td>\nChen<\/a> et al, 2002<\/td>\n<\/tr>\n
Smilax bockii warb extract (flavenoids)<\/td>\nTransactivation<\/td>\nXu<\/a> et al, 2005<\/td>\n<\/tr>\n
Soyasaponin Ab<\/td>\nTransactivation<\/td>\nLee<\/a> et al, 2011<\/td>\n<\/tr>\n
Sphingosine-1-phosphate<\/td>\nTransactivation<\/td>\nHughes<\/a> et al, 2008<\/td>\n<\/tr>\n
Telithromycin<\/td>\nTransactivatiion<\/td>\nLeiva<\/a> et al, 2008<\/td>\n<\/tr>\n
Tetracyclic A<\/td>\nTransactivation (ROS production)<\/td>\nTurbyville<\/a> et al, 2005<\/td>\n<\/tr>\n
Tetrathiomolybdate<\/td>\nTransactivation<\/td>\nPan<\/a> et al, 2002<\/td>\n<\/tr>\n
Trilinolein<\/td>\nTransactivation<\/td>\nLiu<\/a> et al, 2004<\/td>\n<\/tr>\n
Troglitazone<\/td>\nTransactivation<\/td>\nRuan<\/a> et al, 2003<\/td>\n<\/tr>\n
Valerenic acid\/acetylvalerenolic acid<\/td>\nTransactivation<\/td>\nJacobo-Herrera<\/a> et al, 2006<\/td>\n<\/tr>\n
Witheringia solanacea leaf extracts<\/td>\nTransactivation<\/td>\nJacobo-Herrera<\/a> et al, 2006<\/td>\n<\/tr>\n
Wortmannin (fungal metabolite)<\/td>\nTransactivation<\/td>\nReddy<\/a> et al, 1997; Manna<\/a> & Aggarwal, 2000<\/td>\n<\/tr>\n
Xia-Bai-San<\/td>\nTransactivation<\/td>\nYeh<\/a> et al, 2006<\/td>\n<\/tr>\n
Alpha-zearalenol<\/td>\nTransactivation<\/td>\nLi<\/a> et al, 2005<\/td>\n<\/tr>\n
Antithrombin (III)<\/td>\nRelA-p300 interaction; IkB phosphorylation<\/td>\nUchiba<\/a> et al, 2004; Hagiwara<\/a> et al, 2007<\/td>\n<\/tr>\n
Extract of the stem bark of Mangifera indica L.<\/td>\nNF-kB mRNA expression<\/td>\nLeiro<\/a> et al, 2004<\/td>\n<\/tr>\n
Rifampicin<\/td>\nGlucocorticoid receptor modulation<\/td>\nYerramesetti<\/a> et al, 2002<\/td>\n<\/tr>\n
Mangiferin<\/td>\nInhibition of RelA and RelB expression<\/td>\nLeiro <\/a>et al, 2004<\/td>\n<\/tr>\n
Shigella flexneri OspF protein<\/td>\nHistone H3 phosphatase<\/td>\nArbibe<\/a> et al, 2006<\/td>\n<\/tr>\n
Human CD4(+)CD25(hi)Foxp3(+) regulatory T cells (T(regs))<\/td>\nInhibition of Ca2+<\/sup> signals<\/td>\nSchmidt <\/a>et al, 2011<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Miscellaneous inhibitors to NF-kB Inhibitor Molecule Effect or point of inhibition References Azithromycin Inhibited expression of CD40 and CD86 Iwamoto et al, 2011 Conophylline (Ervatamia microphylla) Down regulated TNF-Receptors Gohda et al, 2003 MOL 294 (small molecule) Redox regulated activation of NF-kB Henderson et al, 2002 PEDF (pigment epithelium derived factor) ROS generation Yamagishi et […]<\/p>\n","protected":false},"author":3621,"featured_media":0,"parent":0,"menu_order":8,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/pages\/95"}],"collection":[{"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/users\/3621"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/comments?post=95"}],"version-history":[{"count":50,"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/pages\/95\/revisions"}],"predecessor-version":[{"id":172,"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/pages\/95\/revisions\/172"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/media?parent=95"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}