{"id":163,"date":"2011-02-03T14:17:38","date_gmt":"2011-02-03T19:17:38","guid":{"rendered":"https:\/\/www.bu.edu\/nf-kb\/?page_id=163"},"modified":"2011-06-22T14:18:10","modified_gmt":"2011-06-22T18:18:10","slug":"physiologicalmediators","status":"publish","type":"page","link":"https:\/\/www.bu.edu\/nf-kb\/physiological-mediators\/inducers\/physiologicalmediators\/","title":{"rendered":"Inducers-Physiological Mediators"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Mediator<\/td>\nReference<\/td>\n<\/tr>\n
Acetaldehyde<\/td>\nHsiang<\/a> et al, 2007<\/td>\n<\/tr>\n
Acrp30\/adiponectin<\/td>\nTsao<\/a> et al, 2003; Hattori<\/a> et al, 2007; Tomizawa<\/a> et al, 2008<\/td>\n<\/tr>\n
Activin A<\/td>\nSugatani<\/a> et al, 2003<\/td>\n<\/tr>\n
Adenosine<\/td>\nPorkka-Heiskanen<\/a> et al, 2002<\/td>\n<\/tr>\n
Adiponectin<\/td>\nHug<\/a> & Lodish, 2005; Haugen<\/a> & Drevon, 2007<\/td>\n<\/tr>\n
Adrenomedullin<\/td>\nPleguezuelos<\/a> et al, 2004; Hagi-Pavli<\/a> et al, 2005<\/td>\n<\/tr>\n
AILb-A (from Aeginetia indica)<\/td>\nOkamoto<\/a> et al, 2004<\/td>\n<\/tr>\n
Albumin<\/td>\nDrumm<\/a> et al, 2002; Tang<\/a> et al, 2003<\/td>\n<\/tr>\n
Alginate<\/td>\nYang<\/a> & Jones, 2008<\/td>\n<\/tr>\n
Allergin<\/td>\nCoward<\/a> et al, 2004<\/td>\n<\/tr>\n
Alloferin<\/td>\nRyu<\/a> et al, 2008<\/td>\n<\/tr>\n
Alloxan<\/td>\nZhang<\/a> et al, 2003<\/td>\n<\/tr>\n
Amadori adducts<\/td>\nNevado<\/a> et al, 2005<\/td>\n<\/tr>\n
Amino acid analogs<\/td>\nKretz-Remy<\/a> et al, 1998<\/td>\n<\/tr>\n
Anaphylatoxin C3a and C5a<\/td>\nPan<\/a>, 1998<\/td>\n<\/tr>\n
Angiotensin II (+aldossterone)<\/td>\nLi<\/a> & Brasier, 1996; Li<\/a> et al, 2006; Guo<\/a> et al, 2006<\/td>\n<\/tr>\n
Angiotensin IV<\/td>\nEsteban<\/a> et al, 2005<\/td>\n<\/tr>\n
Angiotensin II type 1-receptor activating antibodies<\/td>\nDragun<\/a> et al, 2005<\/td>\n<\/tr>\n
Anti-CD30 antibody 5F11<\/td>\nBoll et al, 2005<\/td>\n<\/tr>\n
Antiphospholipid antibodies<\/td>\nPierangeli<\/a> et al, 2004<\/td>\n<\/tr>\n
Arachidonic acid<\/td>\nRamakers<\/a> et al, 2007<\/td>\n<\/tr>\n
Areca nut extract<\/td>\nLin<\/a> et al, 2004<\/td>\n<\/tr>\n
Arginine vasopressin<\/td>\nFan<\/a> et al, 2007<\/td>\n<\/tr>\n
Autotaxin<\/td>\nLee<\/a> et al, 2006<\/td>\n<\/tr>\n
Baicalin (plant compound)<\/td>\nPark<\/a> et al, 2004<\/td>\n<\/tr>\n
Basic calcium phosphate crystals<\/td>\nMcCarthy<\/a> et al, 1998<\/td>\n<\/tr>\n
Bronchoalveolar lavage fluid<\/td>\nNys<\/a> et al, 2002; 2005<\/a><\/td>\n<\/tr>\n
Bradykinin<\/td>\nPan<\/a> et al, 1996<\/td>\n<\/tr>\n
Brusatol<\/td>\nCuendet<\/a> et al, 2004<\/td>\n<\/tr>\n
Burn patient serum<\/td>\nLi<\/a> et al, 2005<\/td>\n<\/tr>\n
beta-carotene<\/td>\nPalozza<\/a> et al, 2003<\/td>\n<\/tr>\n
Carrageenan<\/td>\nBorthakur<\/a> et al, 2007<\/td>\n<\/tr>\n
Catalase<\/td>\nJang<\/a> et al, 2004<\/td>\n<\/tr>\n
C2-Ceramide (N-acetyl-sphingosine)<\/td>\nAndrieu<\/a> et al, 1995<\/td>\n<\/tr>\n
Cerulein<\/td>\nGukovsky<\/a> et al, 1998; Steinle<\/a> et al, 1999<\/td>\n<\/tr>\n
Chelidonium majus extract<\/td>\nChung<\/a> et al, 2004<\/td>\n<\/tr>\n
Collagen lattice<\/td>\nXu <\/a>et al, 1998<\/td>\n<\/tr>\n
Collagen Type I<\/td>\nLee<\/a> et al, 1995<\/td>\n<\/tr>\n
Conditioned medium from macrophages<\/td>\nPermana<\/a> et al, 2006<\/td>\n<\/tr>\n
Corn silk<\/td>\nKim<\/a> et al, 2005<\/td>\n<\/tr>\n
Cryptdins<\/td>\nLin<\/a> et al, 2004<\/td>\n<\/tr>\n
Curcuma xanthorrhiza Roxb extract<\/td>\nKim<\/a> et al, 2007<\/td>\n<\/tr>\n
Cystamine<\/td>\nTzang<\/a> et al, 2008<\/td>\n<\/tr>\n
Cysteinyl leukotrines<\/td>\nKawano<\/a> et al, 2003<\/td>\n<\/tr>\n
Deoxycholic acid (bile acid) and derivatives<\/td>\nJenkins<\/a> et al, 2003; Payne<\/a> et al, 2006; Hirano<\/a> et al, 2006<\/td>\n<\/tr>\n
Depression\/early life stress<\/td>\nPace<\/a> et al, 2006<\/td>\n<\/tr>\n
Des-Arg10-kallidin (B1 receptor agonist)<\/td>\nSchanstra<\/a> et al, 1998<\/td>\n<\/tr>\n
1,25-dihydroxycholecalciferol<\/td>\nAdams<\/a> & Teegarden, 2004<\/td>\n<\/tr>\n
Double-stranded polynucleotides<\/td>\nSuzuki <\/a>et al, 1999<\/td>\n<\/tr>\n
f-Met-Leu-Phe<\/td>\nBrowning<\/a> et al, 1997<\/td>\n<\/tr>\n
Endosulfan<\/td>\nHan<\/a> et al, 2007<\/td>\n<\/tr>\n
Epimedium flavonoids<\/td>\nLiu<\/a> et al, 2006<\/td>\n<\/tr>\n
Exosomes secreted from monocytes<\/td>\nMatsumoto<\/a> et al, 2004<\/td>\n<\/tr>\n
Fibrinogen<\/td>\nGuo<\/a> et al, 2004<\/td>\n<\/tr>\n
Ferulic acid derivative<\/td>\nRonchetti<\/a> et al, 2006<\/td>\n<\/tr>\n
Fenretinide<\/td>\nHewson<\/a> et al, 2005<\/td>\n<\/tr>\n
Free fatty acids<\/td>\nTripathy<\/a> et al, 2003<\/td>\n<\/tr>\n
Ganoderma lucidum<\/td>\nKuo<\/a> et al, 2005<\/td>\n<\/tr>\n
Genistein<\/td>\nBorras<\/a> et al, 2006<\/td>\n<\/tr>\n
Geranylgeranylacetone<\/td>\nNishida<\/a> et al, 2007<\/td>\n<\/tr>\n
Ginsenosides<\/td>\nGe<\/a> et al, 2007<\/td>\n<\/tr>\n
(High) glucose<\/td>\nIwasaki<\/a> et al, 2007<\/td>\n<\/tr>\n
beta-glycyrrhetinic acid<\/td>\nShaneyfelt<\/a> et al, 2006<\/td>\n<\/tr>\n
Halothane<\/td>\nBrasil<\/a> et al, 2006<\/td>\n<\/tr>\n
Heat shock protein 25 (Hspb1)<\/td>\nYi<\/a> et al, 2002<\/td>\n<\/tr>\n
Heat shock protein 60 (HSP 60)<\/td>\nKol<\/a> et al, 1999<\/td>\n<\/tr>\n
Hemoglobin<\/td>\nSimoni<\/a> et al, 1998; Ogasawara<\/a> et al, 2009<\/td>\n<\/tr>\n
Hericium erinaceum extract<\/td>\nSon <\/a>et al, 2006<\/td>\n<\/tr>\n
Histamine<\/td>\nTanimoto<\/a> et al, 2007<\/td>\n<\/tr>\n
Homocysteine<\/td>\nMercie<\/a> et al, 2000<\/td>\n<\/tr>\n
Hyaluronan<\/td>\nNoble<\/a> et al, 1996; Scheibner<\/a> et al, 2006<\/td>\n<\/tr>\n
Hydrogen sulfide<\/td>\nZhang<\/a> et al, 2007; Zhi<\/a> et al, 2007<\/td>\n<\/tr>\n
12(R)-Hydroxyeicosatrienoic acid<\/td>\nLaniado-Schwartzman<\/a> et al, 1994<\/td>\n<\/tr>\n
20-Hydroxyeicosatrienoic acid<\/td>\nIshizuka<\/a> et al, 2007<\/td>\n<\/tr>\n
6-Hydroxydopamine<\/td>\nPark<\/a> et al, 2004<\/td>\n<\/tr>\n
hPepT1 (apical di-\/tripeptide transporter<\/td>\nVavricka<\/a> et al, 2004<\/td>\n<\/tr>\n
Kainic acid (Kainate)<\/td>\nKaltschmidt<\/a> et al, 1995; Lubin<\/a> et al, 2005<\/td>\n<\/tr>\n
Lactate<\/td>\nMiller<\/a> et al, 2007<\/td>\n<\/tr>\n
Laminin<\/td>\nArmstrong<\/a> et al, 2008<\/td>\n<\/tr>\n
Leukotriene B4<\/td>\nBrach <\/a>et al, 1992; Huang et al, 2004<\/td>\n<\/tr>\n
L-Glutamate<\/td>\nGuerrini<\/a> et al, 1995<\/td>\n<\/tr>\n
Lipid ozonation products<\/td>\nKafoury<\/a> et al, 2007<\/td>\n<\/tr>\n
Long-term potentiation (LTP)<\/td>\nFreudenthal<\/a> et al, 2004<\/td>\n<\/tr>\n
Lysophosphatidylcholine (LysoPC)<\/td>\nZhu<\/a> et al, 1997; Ryborg<\/a> et al, 2005<\/td>\n<\/tr>\n
alpha-mangostin<\/td>\nShaneyfelt<\/a> et al, 2006<\/td>\n<\/tr>\n
Melanin (from plants)<\/td>\nPugh<\/a> et al, 2005<\/td>\n<\/tr>\n
Mixed meal ingestion (high glucose)<\/td>\nAljada<\/a> et al, 2004; Schiekofer <\/a>et al, 2006<\/td>\n<\/tr>\n
Monosodium urate crystals<\/td>\nJaramillo<\/a> et al, 2004<\/td>\n<\/tr>\n
Monocrotaline (plant toxin)<\/td>\nIwasaki<\/a> et al, 2005<\/td>\n<\/tr>\n
Neuromelanin<\/td>\nWilms<\/a> et al, 2003<\/td>\n<\/tr>\n
Neurotensin<\/td>\nZhao<\/a> et al., 2005<\/td>\n<\/tr>\n
Neutrophil elastase<\/td>\nWalsh<\/a> et al, 2001<\/td>\n<\/tr>\n
Nitric oxide<\/td>\nHemish<\/a> et al, 2003<\/td>\n<\/tr>\n
NSAIDS (sulindac, sulindac sulfone, indomethacin)<\/td>\nLoveridge<\/a> et al, 2007<\/td>\n<\/tr>\n
NS-398 (high dose)<\/td>\nMoalic-Juge<\/a> et al, 2002<\/td>\n<\/tr>\n
Nucleotide activation of P2 receptors<\/td>\nKorcok<\/a> et al, 2005<\/td>\n<\/tr>\n
Oleic acid<\/td>\nPark<\/a> et al, 2003<\/td>\n<\/tr>\n
Optunia polyacantha (prickly pear) polysaccharides<\/td>\nSchepetkin<\/a> et al, 2008<\/td>\n<\/tr>\n
Osteopontin<\/td>\nPhilip<\/a> et al, 2001; Philip<\/a> & Kundu, 2003<\/td>\n<\/tr>\n
PAF (platelet activating factor)<\/td>\nSmith<\/a> & Shearer, 1994; Mutoh<\/a> et al, 1994<\/td>\n<\/tr>\n
Palmitate<\/td>\nCacicedo<\/a> et al, 2004; Ajuwon <\/a>& Spurlock, 2005; Xu<\/a> et al, 2007; Laine<\/a> et al, 2007; Ishikado<\/a> et al, 2009<\/td>\n<\/tr>\n
PCSC (polysaccharide from Poria cocos)<\/td>\nLee<\/a> et al, 2004<\/td>\n<\/tr>\n
Phellinus linteus proteoglycan<\/td>\nKim<\/a> et al, 2004<\/td>\n<\/tr>\n
Pingyangmycin<\/td>\nWu<\/a> et al, 2006<\/td>\n<\/tr>\n
Plaunotol<\/td>\nFu<\/a> et al, 2005<\/td>\n<\/tr>\n
Platelet type arachidonate 12-lipoxygenase<\/td>\nKandouz<\/a> et al, 2003<\/td>\n<\/tr>\n
Polysaccharides of Poria cocos<\/td>\nLee<\/a> & Jeon, 2003<\/td>\n<\/tr>\n
Polysaccharides of Astragalus membranaceus<\/td>\nLee<\/a> & Jeon, 2005<\/td>\n<\/tr>\n
Potassium<\/td>\nKaltschmidt<\/a> et al, 1995<\/td>\n<\/tr>\n
Prolacting and Prolactin N-terminal fragment (16K PRL)<\/td>\nMacotela <\/a>et al, 2002′; Boutet<\/a> et al, 2007; Tabruyn<\/a> et al, 2007<\/td>\n<\/tr>\n
Proteolysis-inducing factor (PIF)<\/td>\nWatchorn<\/a> et al, 2002<\/td>\n<\/tr>\n
Rapamycin<\/td>\nDichtl<\/a> et al, 2005<\/td>\n<\/tr>\n
Regulatory RNA<\/td>\nWatanabe<\/a> et al, 2003<\/td>\n<\/tr>\n
Rev-erbalpha<\/td>\nMigita<\/a> et al, 2004<\/td>\n<\/tr>\n
Rhodiola rhizome aqueous extract<\/td>\nMishra<\/a> et al, 2006<\/td>\n<\/tr>\n
S100B<\/td>\nKogel<\/a> et al, 2004<\/td>\n<\/tr>\n
Salsolinol<\/td>\nWanpen<\/a> et al, 2007<\/td>\n<\/tr>\n
Saturated fatty acids<\/td>\nLee<\/a> et al, 2003<\/td>\n<\/tr>\n
Scopoletin (6-methoxy-7-hydroxycoumarin)<\/td>\nKim<\/a> et al, 2005<\/td>\n<\/tr>\n
Serum amyloid A<\/td>\nJijon<\/a> et al, 2005<\/td>\n<\/tr>\n
Solanum nigrum<\/td>\nAn<\/a> et al, 2005<\/td>\n<\/tr>\n
St John’s Wort (hyperforin)<\/td>\nZhou<\/a> et al, 2004<\/td>\n<\/tr>\n
Streptozotocin<\/td>\nChoi<\/a> et al, 2002<\/td>\n<\/tr>\n
Substance P<\/td>\nGuo<\/a> et al, 2002<\/td>\n<\/tr>\n
Tansy floret polysaccharides<\/td>\nXie<\/a> et al, 2007<\/td>\n<\/tr>\n
Tauroursodeoxycholic acid (TUDCA)<\/td>\nRodrigues<\/a> et al, 2003; Toledo<\/a> et al, 2004<\/td>\n<\/tr>\n
T-cell costimulatory receptor 4-1BB<\/td>\nLee<\/a> et al, 2002<\/td>\n<\/tr>\n
Thioredoxin<\/td>\nHirota<\/a> et al, 1999<\/td>\n<\/tr>\n
Tetrandine<\/td>\nLiou<\/a> et al, 2008<\/td>\n<\/tr>\n
Thrombin<\/td>\nMari<\/a> et al, 1994<\/td>\n<\/tr>\n
Titanium and copper implants<\/td>\nSuska<\/a> et al, 2004<\/td>\n<\/tr>\n
Trypsin (+SLIGRL)<\/td>\nBretschneider<\/a> et al, 1999<\/td>\n<\/tr>\n
Tuberous sclerosis complex<\/td>\nMaldonado<\/a> et al, 2003<\/td>\n<\/tr>\n
Uremic toxins<\/td>\nMotojima<\/a> et al, 2003<\/td>\n<\/tr>\n
Uric acid<\/td>\nHan<\/a> et al, 2006<\/td>\n<\/tr>\n
Very Low density Lipoproteins (VLDL)<\/td>\n Norata<\/a> et al, 2003<\/td>\n<\/tr>\n
Violacein<\/td>\nFerreira<\/a> et al, 2004<\/td>\n<\/tr>\n
Vitamin D3<\/td>\nBerry<\/a> et al, 2002; van Etten<\/a> et al, 2007; Tse<\/a> et al, 2007<\/td>\n<\/tr>\n
White wine<\/td>\nThirunavukkarasu<\/a> et al, 2008<\/td>\n<\/tr>\n
Zinc<\/td>\nKim<\/a> et al, 2006; Bao<\/a> et al, 2007; Rudolf<\/a> & Cervinka, 2008<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\n\n\n\n
beta-carotene<\/td>\nPalozza<\/a> et al, 2003<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Mediator Reference Acetaldehyde Hsiang et al, 2007 Acrp30\/adiponectin Tsao et al, 2003; Hattori et al, 2007; Tomizawa et al, 2008 Activin A Sugatani et al, 2003 Adenosine Porkka-Heiskanen et al, 2002 Adiponectin Hug & Lodish, 2005; Haugen & Drevon, 2007 Adrenomedullin Pleguezuelos et al, 2004; Hagi-Pavli et al, 2005 AILb-A (from Aeginetia indica) Okamoto et […]<\/p>\n","protected":false},"author":3621,"featured_media":0,"parent":105,"menu_order":12,"comment_status":"closed","ping_status":"open","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/pages\/163"}],"collection":[{"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/users\/3621"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/comments?post=163"}],"version-history":[{"count":5,"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/pages\/163\/revisions"}],"predecessor-version":[{"id":654,"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/pages\/163\/revisions\/654"}],"up":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/pages\/105"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/nf-kb\/wp-json\/wp\/v2\/media?parent=163"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}