Welcome to the Center for Multiscale and Translational Mechanobiology, BU’s newest research and education center based in the College of Engineering.<\/p>\n
Mechanobiology, the study of how physical cues affect biological processes, is one of the most untapped but potentially revolutionary avenues for advancing clinical care of injury and disease. Physical cues, such as force and stretch, are known to regulate the behavior of biological systems.\u00a0 In fact, the ability of cells to sense, modulate, and respond to physical cues in their microenvironment is widely regarded as a fundamental aspect of tissue and organ function.<\/p>\n
Mechanobiological phenomena are also intimately involved in the pathogenesis of many diseases and in the capacity for tissues to heal.\u00a0 Advances in biotechnology have enabled remarkable discoveries on the role of mechanical forces and deformation in the inner workings of cells, collective actions of cells, and interactions between cells and their extracellular matrix.<\/p>\n
There is now an opportunity to grow a translational emphasis in mechanobiology research.\u00a0 Achieving this goal will necessarily require approaches that span multiple length scales, from single molecule to multicellular tissues to organs, in order to quantify, and then manipulate, the cellular and subcellular mechanical microenvironments to improve clinical outcomes.<\/p>\n
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Welcome to the Center for Multiscale and Translational Mechanobiology, BU’s newest research and education center based in the College of Engineering. Mechanobiology, the study of how physical cues affect biological processes, is one of the most untapped but potentially revolutionary avenues for advancing clinical care of injury and disease. Physical cues, such as force and […]<\/p>\n","protected":false},"author":14358,"featured_media":0,"parent":0,"menu_order":49,"comment_status":"closed","ping_status":"closed","template":"page-templates\/centers.php","meta":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/mechanobiology\/wp-json\/wp\/v2\/pages\/5"}],"collection":[{"href":"https:\/\/www.bu.edu\/mechanobiology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bu.edu\/mechanobiology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/mechanobiology\/wp-json\/wp\/v2\/users\/14358"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/mechanobiology\/wp-json\/wp\/v2\/comments?post=5"}],"version-history":[{"count":12,"href":"https:\/\/www.bu.edu\/mechanobiology\/wp-json\/wp\/v2\/pages\/5\/revisions"}],"predecessor-version":[{"id":387,"href":"https:\/\/www.bu.edu\/mechanobiology\/wp-json\/wp\/v2\/pages\/5\/revisions\/387"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/mechanobiology\/wp-json\/wp\/v2\/media?parent=5"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}