{"id":2263,"date":"2019-10-31T16:30:40","date_gmt":"2019-10-31T20:30:40","guid":{"rendered":"https:\/\/www.bu.edu\/mcbb\/?post_type=profile&#038;p=2263"},"modified":"2024-12-20T13:38:28","modified_gmt":"2024-12-20T18:38:28","slug":"james-galagan","status":"publish","type":"profile","link":"https:\/\/www.bu.edu\/mcbb\/profile\/james-galagan\/","title":{"rendered":"James Galagan"},"content":{"rendered":"<p>Dr. Galagan\u2019s research is focused on Systems Biology of microbial organisms, specficially Mycobacterium tuberculosis \u2013 the causative agent of tuberculosis \u2013 and the fungus Neurospora crassa. The Galagan Lab is an interdisciplinary group that combines computational biology, genomics, and experimental lab work. Specific interests and projects include:<\/p>\n<ul>\n<li>Using a genomics, computational modeling, and experimental systems-identification techniques to reconstruct the gene regulatory network of M. tuberculosis.<\/li>\n<li>Developing and experimentally validating computational models of microbial metabolism forM. tuberculosis and N. crassa.<\/li>\n<li>Using high-throughput sequencing and comparative sequence analysis to study the functional evolution of M. tuberculosis.<\/li>\n<li>Developing computational methods for genomic data analysis (including gene prediction, gene expression analysis, and polymorphism discovery)<\/li>\n<li>Developing experimental methods for microbial systems identification and analysis, drawing on electrical and mechanical systems identification methods.<\/li>\n<\/ul>\n<p><span style=\"color: #cc0000;\"><a href=\"https:\/\/www.bu.edu\/eng\/profile\/james-galagan-ph-d\/\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"color: #cc0000;\">Department Profile Page<\/a><\/span><\/p>\n","protected":false},"author":16528,"template":"","_links":{"self":[{"href":"https:\/\/www.bu.edu\/mcbb\/wp-json\/wp\/v2\/profile\/2263"}],"collection":[{"href":"https:\/\/www.bu.edu\/mcbb\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bu.edu\/mcbb\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/mcbb\/wp-json\/wp\/v2\/users\/16528"}],"version-history":[{"count":3,"href":"https:\/\/www.bu.edu\/mcbb\/wp-json\/wp\/v2\/profile\/2263\/revisions"}],"predecessor-version":[{"id":4322,"href":"https:\/\/www.bu.edu\/mcbb\/wp-json\/wp\/v2\/profile\/2263\/revisions\/4322"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/mcbb\/wp-json\/wp\/v2\/media?parent=2263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}