{"id":40395,"date":"2026-05-12T15:00:21","date_gmt":"2026-05-12T19:00:21","guid":{"rendered":"https:\/\/www.bu.edu\/hic\/?post_type=profile&#038;p=40395"},"modified":"2026-05-28T09:27:02","modified_gmt":"2026-05-28T13:27:02","slug":"mark-howe","status":"publish","type":"profile","link":"https:\/\/www.bu.edu\/hic\/profile\/mark-howe\/","title":{"rendered":"Mark Howe"},"content":{"rendered":"<article class=\"content-area post-4703 profile type-profile status-publish hentry\">\n<div class=\"profile-single-bio\">\n<p><span>The goal of Mark Howe&#8217;s laboratory is to identify neural circuit principles responsible for adaptively motivating, selecting, and learning actions in changing environments.<\/span><span> The lab<\/span><span> focuses on the basal ganglia, a set of brain regions implicated in regulating motor and cognitive functions on multiple timescales.<\/span><span>\u00a0 A<\/span><span>range of techniques are employed including two-photon microscopy, fiber photometry, and electrophysiology in behaving mice as they perform tasks in virtual environments.<\/span><span>These approaches enable us to investigate neural computations at multiple spatial scales, from large scale networks to subcellular compartments of single neurons.<\/span><span>Basic principles derived from these studies can be applied to better understand neural disorders of the basal ganglia such as Parkinson\u2019s and Huntington\u2019s Disease.<\/span><\/p>\n<\/div>\n<p><a href=\"https:\/\/scholar.google.com\/citations?user=962jqHMAAAAJ&amp;hl=en&amp;oi=ao\" target=\"_blank\" rel=\"noopener\">Google Scholar<\/a><\/p>\n<\/article>\n<p><a href=\"https:\/\/www.bu.edu\/psych\/profile\/mark-howe\/\" target=\"_blank\" rel=\"noopener\">Website<\/a><\/p>\n","protected":false},"author":16894,"template":"","_links":{"self":[{"href":"https:\/\/www.bu.edu\/hic\/wp-json\/wp\/v2\/profile\/40395"}],"collection":[{"href":"https:\/\/www.bu.edu\/hic\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bu.edu\/hic\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/hic\/wp-json\/wp\/v2\/users\/16894"}],"version-history":[{"count":1,"href":"https:\/\/www.bu.edu\/hic\/wp-json\/wp\/v2\/profile\/40395\/revisions"}],"predecessor-version":[{"id":40396,"href":"https:\/\/www.bu.edu\/hic\/wp-json\/wp\/v2\/profile\/40395\/revisions\/40396"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/hic\/wp-json\/wp\/v2\/media?parent=40395"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}