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Joe McGuire, a CAS assistant professor of psychological and brain sciences, uses behavioral studies and brain imaging scans to learn how people make decisions. Photo by Cydney Scott.<\/span><\/em><\/p>\n \u201cAttention, Green Line passengers. There is a service disruption due to some track repairs. Shuttle buses will be available between Kenmore and Arlington stations.\u201d<\/em><\/p>\n Regular MBTA patrons know what it feels like to learn about a service change. Thoughts and questions pile up.\u00a0This train is standing-room only. What if I can\u2019t make the first shuttle? Do I wait for another? I really need to get to that event. How long should I wait? Think of an alternative. How far is the Arlington T station by foot? What\u2019s the price of an Uber to get there?\u00a0<\/em><\/p>\n To\u00a0Joe McGuire<\/a>, this calculus represents the type of real-world experience that drives his basic research into decision-making. In his\u00a0Cognition & Decision Lab<\/a>, McGuire, a College of Arts & Sciences assistant professor of psychological and brain sciences, zeroes in on the neural processes we use to make choices based on available information and our experiences. He develops theories that help us understand how we choose.<\/p>\n \u201cWhen people make decisions, they\u2019re doing it in complex and challenging environments where it\u2019s not always clear what\u2019s going happen if you do this or if you do that, and you might not get to find out for a while,\u201d he says. \u201cWe want to know how people use the information they do have to make the best decision they can.\u201d<\/p>\n For example, deciding how long to wait for a future reward\u2014such as the T shuttle bus\u2014when the timing is uncertain. \u201cOne of the most important things people have to be able to do is to be flexible, to be able to adapt to different situations and environments,\u201d McGuire says. \u201cAnd when you become interested in a question like how does self-control work? it\u2019s possible that the answer will look very different in different situations. In our laboratory tasks, we look at situations where in one case successful performance means being extremely patient and in other cases successful performance means cutting your losses.\u201d<\/p>\n His research, at the intersection of neurobiology and the social sciences, offers the potential for interdisciplinary collaboration, says\u00a0Paul Lipton<\/a>, a CAS research associate professor and director of the undergraduate program in neuroscience. \u201cWe have behavioral economists in the department of economics keyed into understanding the economics of decision-making and the psychology behind the motivation of those decisions,\u201d says Lipton. \u201cThese intersections are becoming stronger and Joe\u2019s work, in neurobiology, is adding to that the brain systems that support different strategies by which one makes decisions.\u201d<\/p>\n Decision science is a field that has gained currency in popular culture and the media. Two of the most famous practitioners have won the Nobel Prize in economics: Daniel Kahneman (in 2002), known for his experiments with his late collaborator Amos Tversky that showed how cognitive biases influence our judgments, and\u00a0Richard Thaler<\/a>\u00a0(in 2017), who has demonstrated that government policies can nudge people to make beneficial decisions, such as picking a mortgage that makes financial sense. Their books, along with those of other researchers, like Angela Duckworth\u00a0(Grit:<\/em>\u00a0The Power of Passion and Perseverance)<\/em>\u00a0and Dan Ariely\u00a0(Predictably Irrational:<\/em>\u00a0The Hidden Forces That Shape Our Decisions),<\/em>\u00a0have been national best sellers.<\/p>\n McGuire, who joined the BU faculty in 2015, attributes the rising interest in this work to a broadly shared urge to understand our actions. It\u2019s a desire he shares. \u201cWhat grabs my interest about it is that it\u2019s puzzling oftentimes why people do what they do, why we ourselves could do what we do,\u201d he says. \u201cWe don\u2019t have perfect insight into even our own decisions and our own cognitive processes. Everyone wants to know why people differ from one another in what they choose and the outcomes they end up with.\u201d<\/p>\n Advances in technology play a role in the field\u2019s rise. Researchers like McGuire use functional magnetic resonance imaging (fMRI) in experiments that correlate changes in brain responses to stimuli. This technique yields a statistical analysis of the magnetic properties of oxygenated blood flowing to parts of the brain that can be rendered in colorful images. (In the images, scientists can see patterns of brain activity evoked by a task or stimulus.) The journal\u00a0Nature<\/em>\u00a0notes that fMRI has emerged as a \u201cworkhorse of brain imaging\u201d since its debut in 1992, and that 2010 saw an average of four studies relying on fMRI published every day.<\/p>\n McGuire uses fMRI and other techniques to test theories about cognitive processes. A 2015 paper he published in\u00a0Nature Neuroscience<\/em><\/a>\u00a0with coauthor Joseph Kable of the University of Pennsylvania, used fMRI to examine how people calculate the costs and benefits of waiting for a reward. An analysis of brain activity suggested that people reassess the value of the situation based on how they experience the delayed reward. Sometimes they wait and other times they do not; they calculate their actions in a dynamic way, rather than from a fixed idea that persisting is the right option every time.<\/p>\n This finding challenges the assumption that persistence is always a good quality. \u201cCertainly in many situations, educational achievement and areas like that, the way to do well is to keep at something,\u201d McGuire says. \u201cOn the other hand, it\u2019s also possible to persist at something so long that it becomes counterproductive. What we\u2019ve been really interested in studying is situations where as time goes on, while you\u2019re waiting for something or working towards something, you might be revising, and updating, and reestimating your expectations about it.\u201d<\/p>\n In one of the meetings of his course Introduction to Cognitive Psychology, the subject is perception. He shows the 60 students a pair of textured patterns on a projection screen. The first is a set of vertical ridges. The second is more difficult to discern, but becomes recognizable as the same pattern slanting at an angle. Why is the second one harder to see?<\/p>\n In discussion with students, McGuire explains how the visual cortex is more responsive to cardinal orientations (think east, west, north, and south) than oblique orientations (the slanted image). We are wired over millennia and then trained to recognize certain patterns. He uses an audio sample to show that the idea applies to hearing: an unfamiliar or unusual speech pattern is harder to comprehend than a familiar delivery. Sometimes, McGuire replies to a student\u2019s question, our expectations for these patterns can change based on our recent experiences, making previously unexpected perceptions more easily discernible.<\/p>\n The lecture and lab course, with outside reading assignments, like the late Oliver Sacks\u2019 writing in\u00a0The New Yorker<\/em>\u00a0about face blindness, in addition to a textbook, has several goals. McGuire wants to show that it\u2019s possible to turn abstract topics like perception and decision-making into measurable actions. He is introducing the would-be neuroeconomics students to typical research questions, but for other students, he says, \u201cit\u2019s useful to know a little bit about how people\u2019s minds work. So whether you\u2019re deciding how to vote or whether you end up working in law or in medicine or any number of things, these topics can matter.\u201d<\/p>\n \u201cWe\u2019re really enthusiastic and excited to have Joe McGuire on our faculty,\u201d says\u00a0Chantal Stern<\/a>, a CAS professor of psychological and brain sciences and director of the\u00a0Cognitive Neuroimaging Center<\/a>.<\/p>\n Stern says McGuire is adept at bringing his research to basic situations that people face. Take waiting for email responses, for example. Some people will reply immediately. Others will respond the next day. After a few days, most people assume they won\u2019t hear back. McGuire creates mathematical models around this cognitive behavior, and through the use of fMRI, examines the interactions between brain structure and brain function.<\/p>\n An example of such decision-making: when McGuire came to Boston to give a lecture to the faculty as part of his job interview, a blizzard threatened to close the campus. Stern told him he could postpone the meeting, and he ended up staying for three days before he could deliver his lecture. \u201cAt that time, he made it clear the wait was worth it for him,\u201d Stern says. \u201cThat is a good example of the sort of thing he is studying at a basic science level\u2014how you make those decisions. They are really complicated decisions from a behavior standpoint. How does a brain figure those out?\u201d<\/p>\n Which brings us back to the T shuttle. The answer about whether to wait for a bus or take an alternative route\u2014as with all decisions in such situations\u2014depends on the information you see now and what you have seen in the past.<\/p>\n \u201cFirst of all, things like persistence are more a matter of getting yourself calibrated properly to your environment than about forcing any particular outcome, always waiting or always not waiting,\u201d McGuire says. \u201cThen, second, when you see what someone else has done, you\u2019re inclined to say they\u2019re chasing sunk costs, or they\u2019re lacking self-control. Sometimes, it\u2019s because they\u2019re working with different information.\u201d<\/p>\nCardinal orientation vs oblique orientation<\/h3>\n