{"id":91193,"date":"2019-11-08T09:38:12","date_gmt":"2019-11-08T13:38:12","guid":{"rendered":"http:\/\/www.bu.edu\/eng\/?p=91193"},"modified":"2024-03-05T11:50:11","modified_gmt":"2024-03-05T16:50:11","slug":"speeding-up-mri-scans-to-save-lives","status":"publish","type":"post","link":"https:\/\/www.bu.edu\/eng\/2019\/11\/08\/speeding-up-mri-scans-to-save-lives\/","title":{"rendered":"Speeding Up MRI Scans to Save Lives"},"content":{"rendered":"<h2>BU researchers design an \u201cintelligent\u201d magnetic metamaterial that could make MRI more affordable and accessible<\/h2>\n<p><strong>By <a href=\"https:\/\/www.bu.edu\/today\/author\/art-jahnke\/\">Art Jahnke<\/a> | Via <a href=\"https:\/\/www.bu.edu\/articles\/2019\/making-mri-scans-faster\/\">The Brink<\/a><\/strong><\/p>\n<p>Boston University researchers have developed a new, \u201cintelligent\u201d metamaterial\u2014which costs less than 10 bucks to build\u2014that could revolutionize magnetic resonance imaging (MRI), making the entire MRI process faster, safer, and more accessible to patients around the world. The technology, which builds on previous metamaterial work by the team, was described in <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adma.201905461\">a new paper in <\/a><em><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adma.201905461\">Advanced Materials<\/a>.<\/em><\/p>\n<p>MRI is used by clinicians to diagnose medical problems by spotting abnormalities that could indicate anything from a torn meniscus to muscular dystrophy. But MRIs are expensive, expose patients to radiation, and they take a long time\u2014often the greater part of an hour for a single scan. Finding enough MRI time for waiting patients can be a problem, even in US hospitals, but in hospitals in countries like India, waiting periods of a year or more can put patients\u2019 lives at risk.<\/p>\n<p>So how do we speed up the MRI process without jeopardizing the quality of imaging? <a href=\"https:\/\/www.bu.edu\/eng\/profile\/xin-zhang-ph-d\/\">Xin Zhang<\/a>, a BU College of Engineering professor of mechanical engineering and a Photonics Center faculty member, and a team of researchers that includes Boston Medical Center radiologist <a href=\"https:\/\/profiles.bu.edu\/Stephan.Anderson\">Stephan Anderson<\/a>, a BU School of Medicine professor of radiology, and <a href=\"https:\/\/profiles.bu.edu\/Xiaoguang.Zhao\">Xiaoguang Zhao <\/a>(ENG\u201916), a MED assistant research professor of radiology, are getting creative with metamaterials to solve the problem.<\/p>\n<p>MRI works by generating a powerful magnetic field and sending radio waves into a patient\u2019s body. \u201cAn MRI\u2019s magnetic field is many thousands of times stronger than the Earth\u2019s magnetic field,\u201d says Zhao. \u201cA precisely orchestrated series of higher-energy radio waves are sent into the human body, and the tissues emit lower-energy radio waves that are received by the MRI to produce an image.\u201d<\/p>\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img src=\"\/eng\/files\/2022\/09\/resized-Onion_image2.jpg\" alt=\"Composite image showing MRI scans of an onion, comparing a standard MRI scan quality to quality of an MRI scan using the newly developed intelligent metamaterial. Text embedded of the standard MRI scan says 'Without Metamaterials' and text above the enhanced MRI scan says 'With Metamaterials.' \" class=\"wp-image-233202\" srcset=\"https:\/\/www.bu.edu\/files\/2019\/11\/resized-Onion_image2.jpg 2000w, https:\/\/www.bu.edu\/files\/2019\/11\/resized-Onion_image2-636x315.jpg 636w, https:\/\/www.bu.edu\/files\/2019\/11\/resized-Onion_image2-768x381.jpg 768w, https:\/\/www.bu.edu\/files\/2019\/11\/resized-Onion_image2-1024x507.jpg 1024w, https:\/\/www.bu.edu\/files\/2019\/11\/resized-Onion_image2-600x297.jpg 600w, https:\/\/www.bu.edu\/files\/2019\/11\/resized-Onion_image2-900x446.jpg 900w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/><figcaption><em>Two MRI images of an onion: the image on the right shows enhancement produced by an intelligent metamaterial developed by Xin Zhang and colleagues. Image courtesy of Zhang et al.<\/em><\/figcaption><\/figure>\n<\/div>\n<p>The quality of MRI images depends to a great extent on what\u2019s called signal-to-noise ratio, or SNR. The higher the SNR, the better the image, and the most direct way to improve the SNR is to turn up the magnetic field. Unfortunately, any increase in the magnetic field also increases the complexity and cost of the MRI, as well as potential risks to patients, whose tissue and whose implanted medical devices in particular are literally heated up by the radiation. For that reason, radiologists who would like to get a better look inside a body cannot simply turn up the magnetic field strength.<\/p>\n<p>So Zhang and her collaborators <a href=\"http:\/\/www.bu.edu\/articles\/2019\/magnetic-metamaterial-mri\">developed a new magnetic metamaterial<\/a> that when placed beside the body part that is the target of a scan boosts the energy emitted by the patient\u2019s body, increasing SNR and improving MRI imaging. The magnetic metamaterial, which is made of simple copper wiring and plastic, was <a href=\"https:\/\/www.nature.com\/articles\/s42005-019-0135-7#Sec1\">published in <\/a><em><a href=\"https:\/\/www.nature.com\/articles\/s42005-019-0135-7#Sec1\">Nature<\/a><\/em><a href=\"https:\/\/www.nature.com\/articles\/s42005-019-0135-7#Sec1\">\u2019s <\/a><em><a href=\"https:\/\/www.nature.com\/articles\/s42005-019-0135-7#Sec1\">Communications Physics<\/a><\/em> in March 2019.<\/p>\n<p>Now, Zhang, Anderson, Zhao, and other team members have taken their development one big step further, developing what they call an \u201cintelligent\u201d metamaterial that selectively boosts the low-energy emissions from the patient\u2019s body and literally turns itself off during the millisecond bursts of high-energy transmission from the machine.<\/p>\n<p>Zhang says that the intelligent metamaterial amplifies SNR by tenfold, which greatly enhances image quality and reduces scan time, opening up a new way to obtain crisper MRI images at very low cost.<\/p>\n<p>\u201cShortening MRI examinations is paramount to maximizing the capacity,\u201d says Anderson. \u201cNot to mention revenue, as well as the overall patient experience of this powerful imaging technology.\u201d<\/p>\n<p><iframe loading=\"lazy\" width=\"971\" height=\"546\" src=\"https:\/\/www.youtube.com\/embed\/bsTsoRIDJ3I\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p>\u201cThe intelligent metamaterial consists of an array of metallic helical resonators closely packed with [a passive sensor],\u201d says Zhao. \u201cWhen the high-energy radio waves are coming in, the metamaterial detects the high energy level and \u2018turns off\u2019 the resonance automatically. With low-energy radio excitation, the metamaterial [turns on] the resonance and enhances the magnetic component of the radio wave.\u201d<\/p>\n<p>That off-time, while only milliseconds long, allows clinicians to use the intelligent metamaterial to enhance the energy sent back to the MRI. It also diminishes the patient\u2019s overall exposure to radio wave radiation and mitigates potential safety concerns, easing the path toward adoption of this technology in clinical imaging.<\/p>\n<p>\u201cWe can now build smart materials that can interact with radio waves intelligently, enhancing the wanted signal while letting the unwanted signal go,\u201d says Zhang.<\/p>\n<p>The researchers estimate that the metamaterial array, developed with the support of the National Institute of Biomedical Imaging and Bioengineering, should cost less than $10 to construct. Even though the current magnetic metamaterial prototype is a flat, thick layer, they expect to adapt it to a flexible, ultra-thin MRI enhancement sheet. Integrated with clinical MRI systems, they say, their newly discovered magnetic metamaterials have the potential to usher in a quantum leap in the performance of MRI.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>BU researchers design an \u201cintelligent\u201d magnetic metamaterial that could make MRI more affordable and accessible By Art Jahnke | Via The Brink Boston University researchers have developed a new, \u201cintelligent\u201d metamaterial\u2014which costs less than 10 bucks to build\u2014that could revolutionize magnetic resonance imaging (MRI), making the entire MRI process faster, safer, and more accessible to [&hellip;]<\/p>\n","protected":false},"author":2322,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[236,257,899,255,240,907,909,252,908,245,1052],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/posts\/91193"}],"collection":[{"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/users\/2322"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/comments?post=91193"}],"version-history":[{"count":2,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/posts\/91193\/revisions"}],"predecessor-version":[{"id":149815,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/posts\/91193\/revisions\/149815"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/media?parent=91193"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/categories?post=91193"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/tags?post=91193"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}