{"id":116039,"date":"2022-03-18T12:33:53","date_gmt":"2022-03-18T16:33:53","guid":{"rendered":"http:\/\/www.bu.edu\/eng\/?p=116039"},"modified":"2023-03-09T14:03:19","modified_gmt":"2023-03-09T19:03:19","slug":"a-simple-test-for-viral-detection","status":"publish","type":"post","link":"https:\/\/www.bu.edu\/eng\/2022\/03\/18\/a-simple-test-for-viral-detection\/","title":{"rendered":"A Simple Test for Viral Detection"},"content":{"rendered":"<h3><strong><em>Nature Biomedical Engineering<\/em> has published Assistant Prof. Alex Green\u2019s development of a new test that uses strands of RNA.<\/strong><\/h3>\n<figure id=\"attachment_106116\" aria-describedby=\"caption-attachment-106116\" style=\"width: 242px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" src=\"\/eng\/files\/2022\/03\/alexander_green3.jpg\" alt=\"\" class=\" wp-image-106116\" width=\"232\" height=\"232\" data-wp-editing=\"1\" \/><figcaption id=\"caption-attachment-106116\" class=\"wp-caption-text\"><em>Assistant Professor Alex Green (BME)<\/em><\/figcaption><\/figure>\n<p><span>Gold-standard lab tests for viruses usually look at several sequences from the virus before determining that a sample is positive, which makes them hard to implement without expensive equipment in centralized facilities. Assistant Professor <a href=\"https:\/\/www.bu.edu\/eng\/profile\/alex-green-ph-d\/\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>Alex Green<\/strong><\/a> and a team of researchers have developed a simple test that embeds the same functionality in a piece of paper. The new test uses strands of RNA that operate like a computer to detect multiple sequences from a virus to return a test result. The RNA computer diagnostic achieves performance that matches approved lab tests when detecting the SARS-CoV-2 virus from saliva samples and can be used to detect multiple strains of the flu virus at the same time.<\/span><\/p>\n<p><img loading=\"lazy\" src=\"\/eng\/files\/2022\/03\/Nature-BME-Alex-green-314-copy.png\" alt=\"\" class=\"alignright wp-image-113181\" width=\"250\" height=\"382\" \/><\/p>\n<p><span>Green\u2019s research,\u00a0<strong><a href=\"https:\/\/www.nature.com\/articles\/s41551-022-00857-7\" target=\"_blank\" rel=\"noopener noreferrer\">Multi-arm RNA Junctions Encoding Molecular Logic Unconstrained by Input Sequence for Versatile Cell-Free Diagnostics<\/a><\/strong><\/span><span>, appears in <a href=\"https:\/\/www.nature.com\/natbiomedeng\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span><strong>Nature Biomedical Engineering<\/strong><\/span><\/a><span>, one of the world&#8217;s top academic journals in the field of biomedical engineering.<\/span><\/span><\/p>\n<p><span><span>\u00a0<\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nature Biomedical Engineering has published Assistant Prof. Alex Green\u2019s development of a new test that uses strands of RNA to return a test result. [&#8230;]<\/p>\n","protected":false},"author":11977,"featured_media":116045,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[236,257,899,541,535,255,540],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/posts\/116039"}],"collection":[{"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/users\/11977"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/comments?post=116039"}],"version-history":[{"count":2,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/posts\/116039\/revisions"}],"predecessor-version":[{"id":170347,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/posts\/116039\/revisions\/170347"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/media\/116045"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/media?parent=116039"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/categories?post=116039"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bu.edu\/eng\/wp-json\/wp\/v2\/tags?post=116039"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}