{"id":2887,"date":"2017-03-08T15:57:36","date_gmt":"2017-03-08T20:57:36","guid":{"rendered":"https:\/\/www.bu.edu\/ctsi\/?page_id=2887"},"modified":"2025-08-06T14:02:31","modified_gmt":"2025-08-06T18:02:31","slug":"the-clinical-trials-network","status":"publish","type":"page","link":"https:\/\/www.bu.edu\/ctsi\/support-for-research\/the-clinical-trials-network\/","title":{"rendered":"The Trial Innovation Network"},"content":{"rendered":"<div style=\"font-family: Arial, sans-serif; max-width: 850px; margin: auto; padding: 20px; background-color: #f9f9f9; border-radius: 12px; box-shadow: 0 4px 12px rgba(0,0,0,0.1);\">\n<h2 style=\"color: #8b0000; text-align: center;\">Trial Innovation Network (TIN)<\/h2>\n<p style=\"font-size: 16px; line-height: 1.6;\"><a href=\"https:\/\/trialinnovationnetwork.org\/elements\/who-we-are\/\">The Trial Innovation Network (TIN)<\/a> <span>is a collaborative initiative within the CTSA Program, since 2016, and is composed of three key partners \u2013 the CTSA Program Hubs, the Trial Innovation Centers (TICs), and the Recruitment Innovation Center (<\/span>RIC that seeks to address critical roadblocks in clinical trials and accelerate the translation of novel interventions into life-saving therapies). Through the CTSA Program, the Boston University Clinical &amp; Translational Science Institute (BU-CTSI) has become a member of the TIN. Through our collaboration, we will be able to provide investigators with a wide range of services and consultations that are designed to assist investigators in the development of proposals into protocols; execute trials better, faster, and more cost-efficiently but, importantly, to be a national laboratory to study, understand and innovate the process of conducting clinical trials.<\/p>\n<div style=\"background-color: #e0f8f2; padding: 20px; border-left: 6px solid #f57c00; margin-top: 20px; border-radius: 8px;\">\n<h3 style=\"margin-top: 0; color: #83224f;\"><strong><span>Key Elements of the Trial Network:<\/span><\/strong><\/h3>\n<ul style=\"line-height: 1.8; font-size: 16px; color: #444;\">\n<li><strong><a href=\"https:\/\/smartirb.org\/\" target=\"_blank\" rel=\"noopener noreferrer\">SMART IRB<\/a> Reliance \u2013 Single IRB model for multisite research<\/strong><\/li>\n<li><strong>Master contracting system<\/strong><\/li>\n<li><strong>Streamlined master protocol and CRF templates<\/strong><\/li>\n<li><strong>Harmonized IT tools for recruitment and trial execution<\/strong><\/li>\n<li><strong>Data-driven recruitment strategies<\/strong><\/li>\n<\/ul>\n<\/div>\n<details style=\"margin-top: 20px; margin-bottom: 15px; border: 1px solid #ccc; border-radius: 6px; background-color: #f9f9f9;\">\n<summary style=\"padding: 12px; font-size: 16px; font-weight: bold; color: #8b0000; cursor: pointer;\">Who is Eligible to Submit a Proposal?<\/summary>\n<div style=\"padding: 10px 20px; font-size: 16px; line-height: 1.6;\">\n<ul>\n<li>Any full time faculty member at Boston University<\/li>\n<li>The investigator must obtain written approval to submit a proposal from the BU CTSI prior to submission to the Trial Innovation Network<\/li>\n<li>If the investigator is proposing work that will be supported by an NIH Institute, he or she must contact a Program Officer at the partner NIH Institute before submitting a proposal to the Trial Innovation Network. The NIH program officer should provide written documentation to the investigator that the proposed application is aligned with the mission of the Institute and that the Program Officer is aware of the request to seek support from the Trial Innovation Network.<\/li>\n<\/ul>\n<\/div>\n<\/details>\n<details style=\"margin-bottom: 15px; border: 1px solid #ccc; border-radius: 6px; background-color: #f9f9f9;\">\n<summary style=\"padding: 12px; font-size: 16px; font-weight: bold; color: #8b0000; cursor: pointer;\">How Do I Submit a Proposal?<\/summary>\n<div style=\"padding: 10px 20px; font-size: 16px; line-height: 1.6;\">\n<ul>\n<li>Interested investigators must contact the BU CTSI Hub Liaison Team (see below) to discuss their proposal and obtain a brief consultation prior to submission. Consultation with the CTSA Program Hub PI\/Trial Innovation Network Hub Liaison Team is required prior to submission.<\/li>\n<li>Proposals submitted to the Trial Innovation Network (TIN) should have a strong scientific hypothesis and should be responsive to each section of the Proposal Intake Form. Detailed information on the proposal form can be found at the Trial Innovation Network website.<\/li>\n<li>For assistance, contact Helia Morris at <a href=\"mailto:hmorris@bu.edu\">hmorris@bu.edu<\/a> or 617-358-7327 or email <a href=\"mailto:ctsisvcs@bu.edu\">ctsisvcs@bu.edu<\/a>.<\/li>\n<li>Visit the <a href=\"https:\/\/trialinnovationnetwork.org\/elements\/trial-innovation-network-proposal-process\/\" target=\"_blank\" rel=\"noopener noreferrer\">TIN Proposal Process page<\/a> for more info.<\/li>\n<\/ul>\n<\/div>\n<\/details>\n<details style=\"margin-bottom: 15px; border: 1px solid #ccc; border-radius: 6px; background-color: #f9f9f9;\">\n<summary style=\"padding: 12px; font-size: 16px; font-weight: bold; color: #8b0000; cursor: pointer;\">What is the Added Value of the TIN?<\/summary>\n<div style=\"padding: 10px 20px; font-size: 16px; line-height: 1.6;\">\n<p>The current state of clinical trials \u2013 across the board and in all disciplines \u2013 presents many opportunities for improvement. The Trial Innovation Network is designed to be a complementary resource and an option for investigators and NIH Institutes to optimize the clinical trials enterprise.<\/p>\n<p><strong><em>For Investigators:<\/em><\/strong><\/p>\n<ul>\n<li>One-stop shopping to implement clinical studies so investigators can focus on the scientific question<\/li>\n<li>TICs and RICs \u2013 expertise in operational innovation and operational excellence<\/li>\n<li>CTSA Program hubs \u2013 broad expertise; large, diverse patient populations<\/li>\n<li>More competitive clinical trials applications submitted to NIH ICs<\/li>\n<\/ul>\n<p><strong><em>For NIH Institutes &amp; Partners:<\/em><\/strong><\/p>\n<ul>\n<li>Shared goal to complete trials and studies on time and within budget<\/li>\n<li>Shared NIH mission to innovate and transform clinical trials and optimize stewardship<\/li>\n<\/ul>\n<\/div>\n<\/details>\n<details style=\"margin-bottom: 15px; border: 1px solid #ccc; border-radius: 6px; background-color: #f9f9f9;\">\n<summary style=\"padding: 12px; font-size: 16px; font-weight: bold; color: #8b0000; cursor: pointer;\">HUB Liaison Team<\/summary>\n<div style=\"padding: 10px 20px; font-size: 16px; line-height: 1.6;\">\n<p>The BU CTSI has established a TIN Hub Liaison Team, which is responsible for coordinating with the TIN. The TIN Liaison team will use their experience and knowledge of the local environment to coordinate Trial Innovation activities at BU and will coordinate activities among other multi-site study stakeholders.<\/p>\n<table style=\"width: 100%; border-collapse: collapse;\">\n<caption style=\"caption-side: top; text-align: left; font-weight: bold; padding-bottom: 10px;\">TIN Hub Liaison Team<\/caption>\n<thead>\n<tr style=\"background-color: #28ca9d; color: #fff;\">\n<th style=\"text-align: left; padding: 8px;\">Role<\/th>\n<th style=\"text-align: left; padding: 8px;\">Team Member<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 8px;\">Principal Investigator<\/td>\n<td style=\"padding: 8px;\"><strong>David M. Center, M.D.<\/strong><br \/>\nAssociate Provost for Translational Research<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px;\">Medical Director<\/td>\n<td style=\"padding: 8px;\"><strong>George O\u2019Connor, M.D.<\/strong><br \/>\nProfessor, Boston University School of Medicine<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px;\">Administrator\/Project Manager<\/td>\n<td style=\"padding: 8px;\"><strong>Helia Morris, MSN<\/strong><br \/>\nExecutive Director, BU-CTSI<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 8px;\">Single IRB Point of Contact<\/td>\n<td style=\"padding: 8px;\"><strong>Matthew Ogrodnik, MS, CIP<\/strong><br \/>\nDirector, Office of Human Research Affairs<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/details>\n<details style=\"margin-bottom: 15px; border: 1px solid #ccc; border-radius: 6px; background-color: #f9f9f9;\">\n<summary style=\"padding: 12px; font-size: 16px; font-weight: bold; color: #8b0000; cursor: pointer;\">What Happens After Submission?<\/summary>\n<div style=\"padding: 10px 20px; font-size: 16px; line-height: 1.6;\">\n<p>Once a proposal is submitted to the TIN, it undergoes review by the Proposal Assessment Team. TIN aims to serve as a national resource to foster excellence, innovation, and optimization in the clinical trial process.<\/p>\n<\/div>\n<\/details>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Trial Innovation Network (TIN) The Trial Innovation Network (TIN) is a collaborative initiative within the CTSA Program, since 2016, and is composed of three key partners \u2013 the CTSA Program Hubs, the Trial Innovation Centers (TICs), and the Recruitment Innovation Center (RIC that seeks to address critical roadblocks in clinical trials and accelerate the translation [&hellip;]<\/p>\n","protected":false},"author":7251,"featured_media":0,"parent":289,"menu_order":18,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/pages\/2887"}],"collection":[{"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/users\/7251"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/comments?post=2887"}],"version-history":[{"count":28,"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/pages\/2887\/revisions"}],"predecessor-version":[{"id":18461,"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/pages\/2887\/revisions\/18461"}],"up":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/pages\/289"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/media?parent=2887"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}