{"id":2366,"date":"2016-10-11T11:13:42","date_gmt":"2016-10-11T15:13:42","guid":{"rendered":"https:\/\/www.bu.edu\/ctsi\/?page_id=2366"},"modified":"2025-07-25T14:47:20","modified_gmt":"2025-07-25T18:47:20","slug":"butmac-research-activities","status":"publish","type":"page","link":"https:\/\/www.bu.edu\/ctsi\/support-for-research\/bumc-thrombotic-microangiopathy-collaborative-butmac\/butmac-research-activities\/","title":{"rendered":"BUTMAC Research Activities"},"content":{"rendered":"<div style=\"font-family: Arial, sans-serif; max-width: 850px; margin: auto; padding: 30px; background-color: #f9f9f9; border-radius: 12px; box-shadow: 0 4px 12px rgba(0,0,0,0.1);\">\n<h2 style=\"color: #8b0000; text-align: center;\">BUTMAC Research Activities<\/h2>\n<details style=\"margin-top: 20px; margin-bottom: 10px; border: 1px solid #ccc; border-radius: 6px; background-color: #ffffff;\">\n<summary style=\"padding: 12px; font-size: 16px; font-weight: bold; color: #8b0000; cursor: pointer;\">Longitudinal Studies<\/summary>\n<div style=\"padding: 10px 20px;\">\n<p style=\"line-height: 1.6; font-size: 16px; color: #333;\">The BUTMAC has an ongoing registry and biobank where clinical and laboratory data could be collected over a long period of time from patients with TMA. The collected information could be used to better understand the cause and the underlying pathophysiology of TMA. Genetic data could be used to better understand the underlying gene mutations or predisposing genes that lead to the development of TMA.<\/p>\n<\/div>\n<\/details>\n<details style=\"margin-bottom: 10px; border: 1px solid #ccc; border-radius: 6px; background-color: #ffffff;\">\n<summary style=\"padding: 12px; font-size: 16px; font-weight: bold; color: #8b0000; cursor: pointer;\">Clinical Trials<\/summary>\n<div style=\"padding: 10px 20px;\">\n<p style=\"line-height: 1.6; font-size: 16px; color: #333;\">Our center participates in clinical trials that aim to study the efficacy and the safety of new medications used for the treatment of TMA. We are currently participating in one clinical trial at BUTMAC. To learn about this trial, please contact <a href=\"mailto:Jean.Francis@bmc.org\">Dr. Jean Francis<\/a> and <a href=\"mailto:Vipul.Chitalia@bmc.org\">Dr. Vipul Chitalia<\/a>.<\/p>\n<\/div>\n<\/details>\n<details style=\"margin-bottom: 10px; border: 1px solid #ccc; border-radius: 6px; background-color: #ffffff;\">\n<summary style=\"padding: 12px; font-size: 16px; font-weight: bold; color: #8b0000; cursor: pointer;\">Basic Research<\/summary>\n<div style=\"padding: 10px 20px;\">\n<p style=\"line-height: 1.6; font-size: 16px; color: #333;\">The samples derived from TMA patients are used to examine the mechanisms promoting the TMA-associated phenotypes in a hypothesis-driven fashion. This part of the research is overseen by Drs. Vipul Chitalia, Katya Ravid, and David Salant.<\/p>\n<\/div>\n<\/details>\n<details style=\"margin-bottom: 10px; border: 1px solid #ccc; border-radius: 6px; background-color: #ffffff;\">\n<summary style=\"padding: 12px; font-size: 16px; font-weight: bold; color: #8b0000; cursor: pointer;\">Get Involved<\/summary>\n<div style=\"padding: 10px 20px;\">\n<p style=\"line-height: 1.6; font-size: 16px; color: #333;\">The success of our clinical mission and research endeavor are only possible with the dedication and the contribution of our patients, their families, and friends. TMA remains an extremely rare disease and very difficult to diagnose. We are dedicated to advance the understanding of TMA and improve our patients\u2019 outcome.<\/p>\n<\/div>\n<\/details>\n<details style=\"margin-bottom: 10px; border: 1px solid #ccc; border-radius: 6px; background-color: #ffffff;\">\n<summary style=\"padding: 12px; font-size: 16px; font-weight: bold; color: #8b0000; cursor: pointer;\">Our Address<\/summary>\n<div style=\"padding: 10px 20px;\">\n<p style=\"line-height: 1.6; font-size: 16px; color: #333;\">715 Albany Street<br \/>\nBoston, MA 02118<br \/>\nPlease contact <a href=\"mailto:Jean.Francis@bmc.org\">Dr. Jean Francis<\/a> and <a href=\"mailto:Vipul.Chitalia@bmc.org\">Dr. Vipul Chitalia<\/a> for more information.<\/p>\n<\/div>\n<\/details>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>BUTMAC Research Activities Longitudinal Studies The BUTMAC has an ongoing registry and biobank where clinical and laboratory data could be collected over a long period of time from patients with TMA. The collected information could be used to better understand the cause and the underlying pathophysiology of TMA. Genetic data could be used to better [&hellip;]<\/p>\n","protected":false},"author":7251,"featured_media":0,"parent":2353,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/pages\/2366"}],"collection":[{"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/users\/7251"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/comments?post=2366"}],"version-history":[{"count":9,"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/pages\/2366\/revisions"}],"predecessor-version":[{"id":18142,"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/pages\/2366\/revisions\/18142"}],"up":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/pages\/2353"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/ctsi\/wp-json\/wp\/v2\/media?parent=2366"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}