NIDDK Current Funding Opportunities

This Funding Opportunity Announcement (FOA) seeks applications for the Implementation Science Hub/Resource Center for the Maternal Health Research Centers of Excellence initiative. This FOA runs in parallel with companion FOAs that seek applications for Research Centers of Excellence (RFA-HD-23-NNN) and an Innovation and Coordinating Hub/Resource Center (RFA-HD-23-NNN).
It is expected that the Implementation Science Hub will serve as a resource to Maternal Health Research Centers of Excellence, with a particular emphasis on assisting in implementing evidence-informed programs, practices and policies to improve maternal health outcomes. The Implementation Science Hub will help bridge the evidence-to-practice gap to support the development and implementation of strategies to inform integrated efforts involving policy and practice changes to improve pregnancy, perinatal, and postpartum care and advance maternal health and maternal health equity. Studies that promote equitable dissemination and implementation of evidence-based interventions among underrepresented communities are strongly encouraged.

Jean Marie Lawrence,Sc.D., M.P.H., M.S.S.A. | RFA-HD-23-037

This Funding Opportunity Announcement (FOA) invites applications to participate as a Research Center as part of the Maternal Health Research Centers of Excellence initiative. The purpose of this initiative is to generate innovative approaches to address preventable maternal mortality, decrease severe maternal morbidity, and promote maternal health equity in partnership with communities that are most affected (i.e., Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, sexual and gender minorities, socioeconomically disadvantaged populations, and underserved rural populations). This initiative will use an integrated multi-level approach encompassing social and biobehavioral research strategies to address the multiple contributing factors that lead to adverse maternal health outcomes and health disparities. Significant contributing factors include comorbid conditions (e.g., hypertension, diabetes, mental illness, and substance use disorders) and social determinants of health, which include structural racism and health care system factors.
The goal of this initiative is for trans-disciplinary researchers to conduct multi-layered novel research approaches that will have the potential to drastically reduce pregnancy-related and pregnancy-associated maternal deaths and decrease severe maternal morbidity. Studies may be interventional (including effectiveness, comparative effectiveness, optimization, or dissemination and implementation studies), or observational (including health services studies, natural experiments, policy analyses) and may assess both short-term and long-term maternal health outcomes. The Research Centers will be uniquely poised to collaborate on studies and projects with other networks and initiatives such as the NICHD Neonatal Research Network and the NICHD Maternal and Pediatric Precision in Therapeutics (MPRINT) initiative.
Jean Marie Lawrence,Sc.D., M.P.H., M.S.S.A. | RFA-HD-23-035

This Funding Opportunity Announcement (FOA) seeks applications for the Data Innovation and Coordinating Hub/Resource Center (hereafter referred to as the Innovation and Data Hub) for the Maternal Health Research Centers of Excellence initiative. This FOA runs in parallel with companion FOAs that seek applications for Research Centers of Excellence (RFA-HD-23-NNN) and an Implementation Science Hub/Resource Center (RFA-HD-23-NNN). It is expected that the Innovation and Data Hub will provide 1) a coordination infrastructure to foster communication and collaboration for participating Research Centers and the Implementation Science Hub under the Maternal Health Centers of Excellence initiative, 2) a centralized resource to support data collection, facilitate curation, and ensure high-quality data, and 3) provide cutting edge biomedical research informatics and data science expertise to maximize data comparability and facilitate data harmonization. The Innovation and Data Hub itself will not generate new experimental data, but rather will serve as a resource, analytical platform, and portal for available analytical and data tools.
Jean Marie Lawrence,Sc.D., M.P.H., M.S.S.A. | RFA-HD-23-036

This funding opportunity announcement (FOA) invites research to develop, characterize, and rigorously validate non-rodent mammalian models of pain, associated outcome measures and/or endpoints that enable translational research for effective pain management. These models are expected to recapitulate molecular, cellular, pathological, behavioral, and/or cognitive aspects of human pain disorders and conditions. Research supported under this FOA is expected to provide well-validated models and measures that facilitate the development of non-opioid analgesic therapeutic interventions with little or no addiction liability.
HEAL Animal Models | RFA-NS-22-070