{"id":5795,"date":"2022-07-28T10:15:51","date_gmt":"2022-07-28T14:15:51","guid":{"rendered":"https:\/\/www.bu.edu\/cte\/?post_type=profile&#038;p=5795"},"modified":"2026-07-22T11:01:29","modified_gmt":"2026-07-22T15:01:29","slug":"samantha-calderazzo","status":"publish","type":"profile","link":"https:\/\/www.bu.edu\/cte\/profile\/samantha-calderazzo\/","title":{"rendered":"Samantha Calderazzo"},"content":{"rendered":"<h4>Bio<\/h4>\n<p><span>Samantha is an MD\/PhD candidate conducting her thesis research in the laboratories of Drs. McKee and Huber examining neuroimmunological processes of disease. She has previously studied neural connectivity, injury, and inflammation, but her current focus is understanding how adaptive immune cells affect pathology in the brains of those with post-traumatic stress disorder and chronic traumatic encephalopthy.<\/span><\/p>\n<h4>Research Interests<\/h4>\n<p><span>Neuroimmunology; inflammation; glial &amp; synapse biology; neuropathology<\/span><\/p>\n<p><a href=\"https:\/\/www.linkedin.com\/in\/samantha-calderazzo-27b583a0\/\" class=\"button\">LinkedIn Profile<\/a><span><\/span><\/p>\n<h4>Selected Publications<\/h4>\n<p><span>1. Orczykowski, M., Calderazzo, SM, Shobin, E, Pessina, MA, Oblak, AL, Finklestein, SP, Kramer, BC, Mortazavi, F, Rosene, DL, and Moore, TL. \u201cCell Based Therapy Reduces Secondary Damage and Increases Extent of Microglial Activation Following Cortical Injury\u201d Brain Res. 2019 Aug 15;1717:147-159. doi: 10.1016\/j.brainres.2019.04.015<\/span><br \/>\n<span>2. Calderazzo, SM, Busch, SE, Moore, TL, Rosene, DL, and Medalla, M. \u201cDistribution and overlap of entorhinal, premotor, and amygdalar connections in the monkey anterior cingulate cortex\u201d J. Comparative Neurology. 2020; 519(4). DOI: https:\/\/doi.org\/10.1002\/cne.24986<\/span><br \/>\n<span>3. Medalla, M.*, Chang, W.*, Calderazzo, SM., Go, V., Tsolias, A., Goodliffe, JW., Pathak, D., De Alba, D., Pessina, MA., Rosene, DL., Buller, B., and Moore, TL. \u201cTreatment with mesenchymal-derived extracellular vesicles reduces injury-related pathology in pyramidal neurons of monkey perilesional ventral premotor cortex EVs reduce injury-related pathology in vPMC\u201d J. Neuroscience. 2020; 2226(19). DOI: https:\/\/doi.org\/10.1523\/JNEUROSCI.2226-19.2020 *Co-first Authors<\/span><br \/>\n<span>4. Calderazzo, SM, Covert, M, De Alba, D, Bowley, BE, Pessina, MA, Rosene, DL, Buller, B, Medalla, M, and Moore, TL. \u201cNeural recovery after cortical injury: Effects of MSC derived extracellular vesicles on motor circuit remodeling in rhesus monkeys\u201d IBRO Neuroscience Reports. 2022; 13: 243-254. https:\/\/doi.org\/10.1016\/j.ibneur.2022.08.001<\/span><\/p>\n","protected":false},"author":20977,"template":"","_links":{"self":[{"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/profile\/5795"}],"collection":[{"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/users\/20977"}],"version-history":[{"count":4,"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/profile\/5795\/revisions"}],"predecessor-version":[{"id":10310,"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/profile\/5795\/revisions\/10310"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/media?parent=5795"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}