{"id":4384,"date":"2017-07-11T14:12:41","date_gmt":"2017-07-11T18:12:41","guid":{"rendered":"https:\/\/www.bu.edu\/cte\/?post_type=profile&p=4384"},"modified":"2026-06-02T09:48:01","modified_gmt":"2026-06-02T13:48:01","slug":"michael-alosco","status":"publish","type":"profile","link":"https:\/\/www.bu.edu\/cte\/profile\/michael-alosco\/","title":{"rendered":"Michael Alosco"},"content":{"rendered":"

Background<\/strong><\/h4>\n

Dr. Alosco is a licensed clinical neuropsychologist and a Professor of Neurology at the Boston University Chobanian & Avedisian School of Medicine where he also serves as the Research Vice Chair, Co-Director of Clinical Research at the BU CTE Center, and Leader of the Boston University Alzheimer\u2019s Disease Research Center Clinical Core. He completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus on neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. Dr. Alosco completed his post-doctoral studies in neuropsychology via NIH-funded training Awards (T32, F32) at the Boston University Alzheimer\u2019s Disease Research Center and CTE Center. In 2018, he became an Assistant Professor of Neurology at the Boston University Chobanian & Avedisian School of Medicine and immediately received NIH\/NINDS K23 Award. He was promoted to Associate Professor in 2019, then to Professor in 2026. Dr. Alosco has published extensively in the fields of Alzheimer\u2019s disease and related dementias, including CTE, and he is the PI of multiple NIH-funded grants. His research has set the stage for biomarker discovery in CTE and the long-term effects of repetitive head impacts on the white matter, and he has made major contributions to plasma biomarker development and validation in Alzheimer\u2019s disease. He has written numerous book chapters, and he is the co-Editor of the Oxford Handbook of Adult Cognitive Disorders<\/em>\u00a0which was published by Oxford University Press in 2019.<\/p>\n

CTE Center Role<\/strong><\/h4>\n

Dr. Alosco is Co-Director of Clinical Research at the BU CTE Center. He is the Project Lead of a multisite NIH\/NINDS-funded U54 that is examining the late neuropathologies of exposure to repetitive head impacts and TBI and resulting clinical syndromes. He oversees studies on risk factors and clinicopathological correlations of CTE.\u00a0Dr. Alosco leads several NIH-funded human subject studies devoted to biomarker development for CTE and the long-term effects of repetitive head impacts on the white matter and vasculature.<\/p>\n

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Selected Publications<\/strong><\/p>\n

    \n
  1. <\/span>Alosco M.L,\u00a0Stein T.D., Tripodis Y, Chua A.S., Huber B.R., Goldstein L.E., Cantu R.C., Katz D.I., Palmisano J.N., Martin B, Cherry J.D., Mahar I, Killiany R.J., McClean M.D., Au R, Alvarez V, Stern R.A., Mez J, McKee A.C. Association of white matter rarefaction, arteriolosclerosis, and tau with dementia in chronic traumatic encephalopathy.\u00a0JAMA Neurol<\/u> <\/strong><\/span>2019;76:1298-1308.<\/li>\n
  2. Alosco M.L.,*\u00a0Tripodis Y,* Baucom Z, Mez J, Stein T.D., Martin B, Haller O, Coneely S, McClean M.D., Nosheny R.L., Mackin S, McKee A.C., Weiner M.W.,** Stern, R.A.** The late contributions of repetitive head impacts and TBI to depression symptoms and cognition.\u00a0Neurology<\/u> <\/strong>2020;95:e793-e804.<\/span><\/li>\n
  3. Alosco M.L.,Cherry J.D., Huber B.R., Tripodis Y, Baucom Z, Kowall N.W.,\u00a0Saltiel N<\/em>, Goldstein L.E., Katz D.I., Dwyer B, Daneshvar D.H., Palmisano J.N., Martin B, Cantu R.C., Stern R.A., Alvarez V.E., Mez J, Stein T.D., McKee A.C. Characterizing tau deposition in chronic traumatic encephalopathy (CTE): Utility of the McKee CTE Staging Scheme.\u00a0Acta Neuropathologica<\/u>\u00a0<\/strong>2020;140:495-512.<\/span><\/li>\n
  4. Sugarman M.A.,McKee A.C., Stein T.D., Tripodis Y, Besser L.M., Martin B, Palmisano J.N., Steinberg E.G., O\u2019Connor M.K., Au R, McClean M, Killiany R, Mez J, Weiner M.W., Kowall N.W., Stern R.A.,*\u00a0Alosco M.L<\/strong>.* Failure to detect an association between self-reported traumatic brain injury and Alzheimer\u2019s disease neuropathology and dementia.\u00a0Alzheimers Dement<\/u><\/strong>\u00a02019;15:686-698.<\/span><\/li>\n
  5. Alosco M.L.,\u00a0Mez J, Tripodis Y, Kiernan P.T., Abdolmohammadi B, Murphy L, Kowall N.W., Stein T.D., Huber B.R., Goldstein L.E., Cantu R.C., Katz D.I., Chaisson C.E., Martin B, Solomon T.M., McClean M.D., Daneshvar D.H., Nowinski C.J., Stern R.A., McKee A.C. Age of first exposure to tackle football and chronic traumatic encephalopathy.\u00a0Annals of Neurology<\/u> <\/strong>2018;83:886-901.<\/span><\/li>\n
  6. Alosco M.L.,\u00a0Tripodis Y, Fritts N.G., Heslegrave A, Baugh C.M., Conneely S, Mariani M, Martin B.M., Frank S, Mez J, Stein T.D., Cantu R.C., McKee A.C., Shaw L.M., Trojanowski J.Q., Blennow K, Zetterberg H, Stern R.A. Cerebrospinal fluid tau,\u00a0A\u03b2, and sTREM2 in former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation, and neurodegeneration.\u00a0Alzheimers Dement<\/u> <\/strong>2018;14:1159-1170.<\/span><\/li>\n
  7. Alosco M.L.,\u00a0Koerte I.K., Tripodis Y, Mariania M, Chua A.S., Jarnagin J, Rahimpour Y, Puzo C, Healy R.C., Martin B, Chaisson C.E., Cantu R.C., Au R, McClean M, McKee A.C., Lin A.P., Shenton M.E., Killiany R.J., Stern R.A. White matter signal abnormalities in former National Football League players.\u00a0Alzheimers Dementia (Amst<\/u>) 2017;10:56-65.<\/span><\/li>\n
  8. Alosco M.L.,\u00a0Kasimis A.B., Stamm J.M., Chua A.S., Baugh C.M., Daneshvar D.H., Robbins C.A., Mariani M, Hayden J, Conneely S, Au R, Torres A, McClean M.D., McKee A.C., Cantu R.C., Mez J, Nowinski C.J., Martin B.M., Chaisson C.E., Tripodis Y, Stern R.A. Age of first exposure to American football and long-term neuropsychiatric and cognitive outcomes.\u00a0Transl Psychiatry<\/u> <\/strong>2017;7:1-8.<\/span><\/li>\n<\/ol>\n","protected":false},"author":12906,"template":"","_links":{"self":[{"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/profile\/4384"}],"collection":[{"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/users\/12906"}],"version-history":[{"count":23,"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/profile\/4384\/revisions"}],"predecessor-version":[{"id":10251,"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/profile\/4384\/revisions\/10251"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/cte\/wp-json\/wp\/v2\/media?parent=4384"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}