The mission of my lab is twofold: to reveal the neural circuit mechanisms of memory storage and retrieval, and to artificially modulate memories to combat maladaptive states. We will do so in a multi-disciplinary fashion by combining virus engineering strategies, immunohistochemistry and physiology, optogenetics and functional imaging of targeted populations in vivo, and a battery of behavioral assays. Our technical repertoire, of course, will evolve as our studies evolve.<\/p>\n
Given that any given brain region interacts with numerous targets along exquisitely precise spatial and temporal dimensions — nothing in the brain exists in a vacuum — we’ll study the circuit-wide and behavioral manifestations of learning and memory across a variety of structurally and functionally connected areas, including, but not limited to, the hippocampus, amygdala, and prefrontal cortex. For example, I believe that a systems-level analysis of memory that perturbs genetically defined, projection-specific cell-types, while simultaneously surveying their real-time physiological dynamics, is a tractable experimental path towards understanding, and controlling, this seemingly ephemeral process.<\/p>\nRamirez Group<\/a>\nGoogle Scholar<\/a>\n","protected":false},"author":12181,"template":"","_links":{"self":[{"href":"https:\/\/www.bu.edu\/csn\/wp-json\/wp\/v2\/profile\/1270"}],"collection":[{"href":"https:\/\/www.bu.edu\/csn\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bu.edu\/csn\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/csn\/wp-json\/wp\/v2\/users\/12181"}],"version-history":[{"count":6,"href":"https:\/\/www.bu.edu\/csn\/wp-json\/wp\/v2\/profile\/1270\/revisions"}],"predecessor-version":[{"id":3958,"href":"https:\/\/www.bu.edu\/csn\/wp-json\/wp\/v2\/profile\/1270\/revisions\/3958"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/csn\/wp-json\/wp\/v2\/media?parent=1270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}