Combining the Power of Biobanks and System Biology Approaches for Better Infectious Disease Prevention and Treatment

The clinical outcome of any infectious disease can vary widely, ranging from asymptomatic cases to fatal outcomes, depending on a complex interplay between the pathogen, host, and environment. Traditionally, the study of infectious diseases has focused primarily on the pathogen, which has limited our understanding of the environmental and host-specific factors that influence disease susceptibility and severity. Addressing this gap is crucial for developing effective strategies and treatments for infectious disease control. In this talk, I will present our research on the role of human genetic factors and social determinants of health in infectious disease outcomes. I will also demonstrate how we can harness the power of large-scale biobanks and systems biology approaches to gain deeper insights into the complex mechanisms that determine the clinical outcomes of infectious diseases.