{"id":524,"date":"2014-01-06T12:32:52","date_gmt":"2014-01-06T17:32:52","guid":{"rendered":"https:\/\/www.bu.edu\/computationalimmunology\/?post_type=profile&p=524"},"modified":"2014-01-06T13:21:40","modified_gmt":"2014-01-06T18:21:40","slug":"garnett-h-kelsoe","status":"publish","type":"profile","link":"https:\/\/www.bu.edu\/computationalimmunology\/people\/garnett-h-kelsoe\/","title":{"rendered":"Garnett H. Kelsoe"},"content":{"rendered":"
\n

Doctor Kelsoe and his collaborators have long been interested in the biology of B lymphocytes and have worked to demonstrate stochastic variable (V) gene segment use in the primary B-cell repertoire; the migrations of antigen-activated T and B lymphocytes during humoral responses; the germinal center as the primary site of V(D)J hypermutation and affinity-driven selection; the role of complement in the germinal center response and affinity maturation of serum antibodies; the nature, role, and distribution of cryptic, V(D)J recombination signals in the mammalian genome; and the basic mechanisms of central B-cell tolerance.<\/p>\n","protected":false},"author":7993,"template":"","_links":{"self":[{"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/profile\/524"}],"collection":[{"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/users\/7993"}],"version-history":[{"count":2,"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/profile\/524\/revisions"}],"predecessor-version":[{"id":527,"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/profile\/524\/revisions\/527"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/media?parent=524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}