{"id":345,"date":"2013-11-08T19:33:16","date_gmt":"2013-11-09T00:33:16","guid":{"rendered":"https:\/\/www.bu.edu\/computationalimmunology\/?page_id=345"},"modified":"2013-11-12T13:41:09","modified_gmt":"2013-11-12T18:41:09","slug":"publications","status":"publish","type":"page","link":"https:\/\/www.bu.edu\/computationalimmunology\/research\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<hr \/>\n<h2 style=\"text-align: justify;\">2013<\/h2>\n<ul style=\"text-align: justify;\">\n<li>Wesemann, DR, AJ Portuguese, RM Meyers, MP Gallagher, K Cluff-Jones, JM Magee, RA Panchakshari, SJ Rodigs, <strong>TB Kepler<\/strong>, FW Alt (2013) Microbial colonization influences early B-lineage development in the gut lamina propria. <em>Nature <\/em>501: 112\u2013115. <a href=\"http:\/\/www.nature.com\/nature\/journal\/vaop\/ncurrent\/full\/nature12496.html\">doi:10.1038\/nature12496<\/a>.<\/li>\n<li><strong>Kepler TB<\/strong>. (2013) Reconstructing a B-cell clonal lineage. I. Statistical inference of unobserved ancestors [v1; ref status: indexed, http:\/\/f1000r.es\/z6] F1000Research2:103 (<a href=\"http:\/\/f1000research.com\/articles\/2-103\/v1\">doi: 10.12688\/f1000research.2-103.v1<\/a>).<\/li>\n<li>Liao, H-X, R Lynch, T Zhou, F Gao, SM Alam, SD Boyd, AZ Fire, KM Roskin, CA Schramm, Z Zhang, J Zhu, L Shapiro, JC Mullikin, S Gnanakaran, P Hraber, K Wiehe, G Kelsoe, G Yang, S-M Xia, DC Montefiori, R Parks, KE Lloyd, RM Scearce, KA Soderberg, M Cohen, G Kamanga, MK Louder, LM Tran, Y Chen, F Cai, S Chen, S Moquin, X Du, MG Joyce, S Srivatsan, B Zhang, A Zheng, GM Shaw, BH Hahn, <strong>TB Kepler<\/strong>, BTM Korber, PD Kwong, JR Mascola, BF Haynes (2013) Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. <em>Nature <\/em>496, 469-476.\u00a0<a href=\"http:\/\/www.nature.com\/nature\/journal\/v496\/n7446\/full\/nature12053.html\">doi:10.1038\/nature12053<\/a>.<\/li>\n<li>Ciupe, SM, BH Devlin, LM Markert, <strong>TB Kepler<\/strong> (2013) Quantification of total T-cell receptor diversity by flow cytometry and spectratyping, <em>BMC Immunology<\/em> 14:35. <a href=\"http:\/\/www.biomedcentral.com\/1471-2172\/14\/35\">doi: 10.1186\/1471-2172-14-35<\/a>.<\/li>\n<li>Yang G, TM Holl,Y Liu, Y Li, X Lu, NI Nicely, <strong>TB Kepler<\/strong>, SM Alam, HX Liao, DW Cain, L Spicer, JL Vandeberg, BF Haynes, G Kelsoe (2013) Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies.<em> J. Exp. Med<\/em>. 210: 241-56.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23359068\">doi: 10.1084\/jem.20121977<\/a>.<\/li>\n<li>Chan C, M Billard, S Ramirez, H Schmidl, E Monson, and <strong>TB Kepler<\/strong> (2013) A model for migratory B cell oscillations from receptor down-regulation induced by external chemokine fields. <em>Bull. Math. Biol<\/em>. 75: 185-205.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23296998\">doi: 10.1007\/s11538-012-9799-9<\/a>.<\/li>\n<li>H-X Liao, M Bonsignori, SM Alam, JS McLellan, GD Tomaras, MA Moody, DM Kozink, K-K Hwang, X Chen, C-Y Tsao, P Liu, X Lu, RJ Parks, DC Montefiori, G Ferrari, J Pollara, M Rao, KK Peachman, S Santra, NL Letvin, N Karasavvas, Z-Y Yang, K Dai, M Pancera, J Gorman, K Wiehe, NI Nicely, S Rerks-Ngarm, S Nitayaphan, J Kaewkungwal, P Pitisuttithum, J Tartaglia, F Sinangil, JH Kim, NL Michael, <strong>TB Kepler<\/strong>, PD Kwong, JR Mascola, GJ Nabel, A Pinter, S Zolla-Pazner  BF Haynes (2013) HIV-1 Vaccine Induces Antibodies Against a V1\/V2 Structurally Heterogeneous Site of Immune Pressure. <em>Immunity <\/em>38: 176-86. PMC3569735.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23313589\">doi: 10.1016\/j.immuni.2012.11.011<\/a>.<\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\">2012<\/h2>\n<ul>\n<li style=\"text-align: justify;\">Schmidt AG, H Xu, AR Khan, T O\u2019Donnell, S Khurana, LR King, J Manischewitz, H Golding, P Suphaphiphat, A Carfi, E Settembre, PR Dormitzer, <strong>T B Kepler<\/strong>, R Zhang, MA Moody, BF Haynes, HX Liao, DE Shaw, SC Harrison (2012) Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.<em> Proc Natl Acad Sci USA<\/em> 110: 264-9. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3538208\/\">PMC3538208<\/a>.<\/li>\n<li style=\"text-align: justify;\">Manolopoulou I, <strong>TB Kepler<\/strong>, DM Merl (2012) Mixtures of Gaussian wells: Theory, computation, and application. <em>Comput Stat Data Anal<\/em>, 56:3809-3820. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22754052\">PMC3384503<\/a>.<\/li>\n<li style=\"text-align: justify;\">Haynes BF, G Kelsoe, SC Harrison, <strong>TB Kepler<\/strong> (2012) B Cell Lineage Immunogen Design:  A New Approach To Vaccine Development. <em>Nat Biotech<\/em>, 30: 423-433. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22565972\">PMC3512202<\/a>.<\/li>\n<li style=\"text-align: justify;\">Manolopoulou I, Matheu MP, Cahalan MD, West M, <strong>Kepler TB<\/strong> (2012) Bayesian spatio-dynamic modelling in cell motility studies: Learning nonlinear taxic fields guiding the immune response. <em>J Am Stat Assoc<\/em>. 499: 855-65. <a href=\"http:\/\/amstat.tandfonline.com\/doi\/full\/10.1080\/01621459.2012.655995#.UoJ2DhvEMt1\">doi:10.1080\/01621459.2012.655995<\/a><\/li>\n<li style=\"text-align: justify;\">Bonsignori M, Montefiori DC, Wu X, Chen X, Hwang KK, Tsao CY, Kozink DM, Parks RJ, Tomaras GD, Crump JA, Kapiga SH, Sam NE, Kwong PD, <strong>Kepler TB<\/strong>, Liao HX, Mascola JR, Haynes BF (2012) Two Distinct Broadly Neutralizing Antibody Specificities of Different Clonal Lineages in a Single HIV-1-infected Donor: Implications for Vaccine Design. <em>J. Virol<\/em>. 86: 4688-92. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3318651\/\">PMC3318651<\/a>.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>2013 Wesemann, DR, AJ Portuguese, RM Meyers, MP Gallagher, K Cluff-Jones, JM Magee, RA Panchakshari, SJ Rodigs, TB Kepler, FW Alt (2013) Microbial colonization influences early B-lineage development in the gut lamina propria. Nature 501: 112\u2013115. doi:10.1038\/nature12496. Kepler TB. (2013) Reconstructing a B-cell clonal lineage. I. Statistical inference of unobserved ancestors [v1; ref status: indexed, [&hellip;]<\/p>\n","protected":false},"author":7993,"featured_media":0,"parent":153,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/pages\/345"}],"collection":[{"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/users\/7993"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/comments?post=345"}],"version-history":[{"count":27,"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/pages\/345\/revisions"}],"predecessor-version":[{"id":512,"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/pages\/345\/revisions\/512"}],"up":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/pages\/153"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/computationalimmunology\/wp-json\/wp\/v2\/media?parent=345"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}