{"id":8069,"date":"2011-02-01T15:33:02","date_gmt":"2011-02-01T20:33:02","guid":{"rendered":"https:\/\/www.bu.edu\/chemistry\/?p=8069"},"modified":"2011-05-10T10:50:16","modified_gmt":"2011-05-10T14:50:16","slug":"stephenson-group-receives-nih-funding-for-alkaloid-synthesis","status":"publish","type":"post","link":"https:\/\/www.bu.edu\/chemistry\/2011\/02\/01\/stephenson-group-receives-nih-funding-for-alkaloid-synthesis\/","title":{"rendered":"NIH Funds Alkaloid Synthesis Research"},"content":{"rendered":"<figure id=\"attachment_7861\" aria-describedby=\"caption-attachment-7861\" style=\"width: 150px\" class=\"wp-caption alignright\"><a href=\"https:\/\/www.bu.edu\/chemistry\/people\/faculty\/stephenson\/\"><img loading=\"lazy\" class=\"size-medium wp-image-7861 \" title=\"Prof Corey Stephenson\" src=\"\/chemistry\/files\/2009\/06\/Stephenson_BI-Photo_2-452x300.jpg\" alt=\"Prof Corey Stephenson\" width=\"140\" height=\"92\" srcset=\"https:\/\/www.bu.edu\/chemistry\/files\/2009\/06\/Stephenson_BI-Photo_2-452x300.jpg 452w, https:\/\/www.bu.edu\/chemistry\/files\/2009\/06\/Stephenson_BI-Photo_2.jpg 600w\" sizes=\"(max-width: 140px) 100vw, 140px\" \/><\/a><figcaption id=\"caption-attachment-7861\" class=\"wp-caption-text\">Professor Corey Stephenson<\/figcaption><\/figure>\n<p><a href=\"https:\/\/www.bu.edu\/chemistry\/people\/faculty\/stephenson\/\">Professor Corey Stephenson<\/a> and his <a href=\"http:\/\/people.bu.edu\/crjsteph\/\" target=\"_blank\">group<\/a> have received a 5-year, $1.7 million\u00a0 award from the <a href=\"http:\/\/www.nih.gov\/\" target=\"_blank\">National Institutes of Health<\/a> (<a href=\"http:\/\/www.nigms.nih.gov\/\" target=\"_blank\">NIGMS<\/a>) to develop novel catalytic approaches to the synthesis of alkaloid natural products. These visible light-mediated methods provide innovative avenues toward challenging molecular architectures with broad biological activity.<\/p>\n<p>The <a href=\"http:\/\/people.bu.edu\/crjsteph\/\" target=\"_blank\">Stephenson Group<\/a> focuses on performing syntheses in an environmentally conscious way. By using visible light, they prepare waste-free, non-toxic &#8220;reagent&#8221; complex natural products.\u00a0 Since most organic molecules do not\u00a0 absorb visible light, they can use photosensitive catalysts (widely studied for their photophysical properties) to carry out transformations under mild conditions in the presence of otherwise reactive functional groups. These new chemical reactions will enable the synthesis of biologically active natural products implicated in cancer, infection, and cardiovascular disease.<\/p>\n<figure id=\"attachment_8076\" aria-describedby=\"caption-attachment-8076\" style=\"width: 130px\" class=\"wp-caption alignleft\"><a href=\"\/chemistry\/files\/2011\/01\/Stephenson_Alkaloid_Synthesis.jpg\" target=\"_blank\"><img loading=\"lazy\" class=\"size-medium wp-image-8076  \" title=\"Professor Corey Stephenson. Alkaloid Synthesis Using Visible Light\" src=\"\/chemistry\/files\/2011\/01\/Stephenson_Alkaloid_Synthesis-225x300.jpg\" alt=\"Professor Corey Stephenson. Alkaloid Synthesis Using Visible Light\" width=\"120\" height=\"160\" srcset=\"https:\/\/www.bu.edu\/chemistry\/files\/2011\/01\/Stephenson_Alkaloid_Synthesis-225x300.jpg 225w, https:\/\/www.bu.edu\/chemistry\/files\/2011\/01\/Stephenson_Alkaloid_Synthesis.jpg 768w\" sizes=\"(max-width: 120px) 100vw, 120px\" \/><\/a><figcaption id=\"caption-attachment-8076\" class=\"wp-caption-text\">Alkaloid Synthesis Using Visible Light<\/figcaption><\/figure>\n<figure id=\"attachment_8075\" aria-describedby=\"caption-attachment-8075\" style=\"width: 130px\" class=\"wp-caption alignleft\"><a href=\"\/chemistry\/files\/2011\/01\/Stephenson_Alkaloid_Synthesis_Compound.jpg\" target=\"_blank\"><img loading=\"lazy\" class=\"size-medium wp-image-8075   \" title=\"Alkaloid Synthesis: Plectosphaeroic Acid A\" src=\"\/chemistry\/files\/2011\/01\/Stephenson_Alkaloid_Synthesis_Compound-253x300.jpg\" alt=\"Professor Stephenson. Alkaloid Synthesis Compound\" width=\"120\" height=\"143\" srcset=\"https:\/\/www.bu.edu\/chemistry\/files\/2011\/01\/Stephenson_Alkaloid_Synthesis_Compound-253x300.jpg 253w, https:\/\/www.bu.edu\/chemistry\/files\/2011\/01\/Stephenson_Alkaloid_Synthesis_Compound.jpg 866w\" sizes=\"(max-width: 120px) 100vw, 120px\" \/><\/a><figcaption id=\"caption-attachment-8075\" class=\"wp-caption-text\">Plectosphaeroic Acid A<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>The Stephenson Group Receives NIH Funding for Alkaloid Synthesis using Visible Light. These visible light-mediated methods provide innovative avenues toward challenging molecular architectures with broad biological activity. <\/p>\n","protected":false},"author":1531,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[114,997,135,1470,1526],"tags":[4247,1610,1482,4245,9216,4246],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/posts\/8069"}],"collection":[{"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/users\/1531"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/comments?post=8069"}],"version-history":[{"count":57,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/posts\/8069\/revisions"}],"predecessor-version":[{"id":8817,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/posts\/8069\/revisions\/8817"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/media?parent=8069"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/categories?post=8069"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/tags?post=8069"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}