{"id":14717,"date":"2015-06-03T16:46:26","date_gmt":"2015-06-03T20:46:26","guid":{"rendered":"https:\/\/www.bu.edu\/chemistry\/?p=14717"},"modified":"2015-06-03T17:36:08","modified_gmt":"2015-06-03T21:36:08","slug":"nanoparticle-based-drug-delivery-system-receives-ignition-award","status":"publish","type":"post","link":"https:\/\/www.bu.edu\/chemistry\/2015\/06\/03\/nanoparticle-based-drug-delivery-system-receives-ignition-award\/","title":{"rendered":"Nanoparticle-based Drug Delivery System Receives Ignition Award"},"content":{"rendered":"<figure id=\"attachment_14718\" aria-describedby=\"caption-attachment-14718\" style=\"width: 127px\" class=\"wp-caption alignleft\"><a href=\"\/chemistry\/files\/2015\/06\/Grinstaff-2009HSb.jpg\"><img loading=\"lazy\" src=\"\/chemistry\/files\/2015\/06\/Grinstaff-2009HSb.jpg\" alt=\"Grinstaff 2009HSb\" class=\"wp-image-14718\" height=\"158\" width=\"117\" srcset=\"https:\/\/www.bu.edu\/chemistry\/files\/2015\/06\/Grinstaff-2009HSb.jpg 288w, https:\/\/www.bu.edu\/chemistry\/files\/2015\/06\/Grinstaff-2009HSb-222x300.jpg 222w\" sizes=\"(max-width: 117px) 100vw, 117px\" \/><\/a><figcaption id=\"caption-attachment-14718\" class=\"wp-caption-text\">Prof. Mark Grinstaff<\/figcaption><\/figure>\n<figure id=\"attachment_14721\" aria-describedby=\"caption-attachment-14721\" style=\"width: 111px\" class=\"wp-caption alignleft\"><a href=\"\/chemistry\/files\/2015\/06\/Aaron-Colby.jpg\"><img loading=\"lazy\" src=\"\/chemistry\/files\/2015\/06\/Aaron-Colby.jpg\" alt=\"Aaron Colby\" class=\"wp-image-14721\" height=\"155\" width=\"101\" srcset=\"https:\/\/www.bu.edu\/chemistry\/files\/2015\/06\/Aaron-Colby.jpg 445w, https:\/\/www.bu.edu\/chemistry\/files\/2015\/06\/Aaron-Colby-195x300.jpg 195w\" sizes=\"(max-width: 101px) 100vw, 101px\" \/><\/a><figcaption id=\"caption-attachment-14721\" class=\"wp-caption-text\">Dr. Aaron Colby<\/figcaption><\/figure>\n<p><strong>Professor <a href=\"https:\/\/www.bu.edu\/chemistry\/people\/faculty\/grinstaff\/\">Mark Grinstaff<\/a><\/strong> and postdoctoral scientist, <strong>Dr. Aaron Colby<\/strong>, have received a <a href=\"http:\/\/www.bu.edu\/otd\/funding-opportunities\/ignition\/\">2015 Ignition Award<\/a> from the BU Office of Technology Development to develop a nanoparticle-based drug delivery system for the treatment of mesothelioma.\u00a0 Mesothelioma is a rare form of cancer that develops from cells of the mesothelium, the protective lining that covers many of the internal organs of the body.<\/p>\n<p>The purpose of the Ignition Awards program is to validate early-stage projects with clear commercial and medical\u00a0 potential.\u00a0 This project was selected because, to date, there is no effective cure for mesothelioma and there is no way to prevent local recurrence. In this research, the Grinstaff group is\u00a0 developing a novel nanoparticle-based drug delivery system for localizing intraperitoneally administered chemotherapy directly to the site of established disease that remains following surgical resection procedures.\u00a0 The result is increased tumor-tissue drug concentrations and, subsequently, reduced recurrence and improved patient survival.<\/p>\n<p>Since its establishment in 2007, the <a href=\"http:\/\/www.bu.edu\/otd\/funding-opportunities\/ignition\/past-winners\/\">Ignition Awards Program<\/a> has funded 46 project.\u00a0 Of these projects, 10 have been developed by Chemistry faculty.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Professor Mark Grinstaff and postdoctoral scientist, Dr. Aaron Colby, have received a 2015 Ignition Award from the BU Office of Technology Development to develop a nanoparticle-based drug delivery system for the treatment of mesothelioma.\u00a0 Mesothelioma is a rare form of cancer that develops from cells of the mesothelium, the protective lining that covers many of [&hellip;]<\/p>\n","protected":false},"author":1532,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[63],"tags":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/posts\/14717"}],"collection":[{"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/users\/1532"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/comments?post=14717"}],"version-history":[{"count":3,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/posts\/14717\/revisions"}],"predecessor-version":[{"id":14723,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/posts\/14717\/revisions\/14723"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/media?parent=14717"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/categories?post=14717"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bu.edu\/chemistry\/wp-json\/wp\/v2\/tags?post=14717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}