Laurel Schafer Colloquium

Laurel Schafer from the University of British Columbia will present a seminar.

Title: Ureate Early Transition Metal Complexes. The Catalytic Addition of Amines to Alkenes and Beyond

Abstract: Early transition metal catalyzed hydroaminoalkylation is a Green Chemistry approach for the synthesis of selectively substituted amines for the pharmaceutical, agrochemical and functional materials industries. Hydroaminoalkylation allows for the direct reaction of amines with alkenes and recent advances have shown that aryl- and alkylamines, as well as N-heterocycles, react with terminal and internal alkenes to access diverse products. State-of-the-art catalysts feature N,O-chelating ureate ligands, with tuneable steric and electronic features and flexible bonding modes, to enable efficient C-H bond activation and Csp3-Csp3 bond formation. This catalytic technology can be used on large scale to access amine-containing, self-healing and adhesive materials with tuneable properties for application as underwater adhesives, anti-corrosion coatings and more.