Optical Spectroscopy for Improved PCP Screening of Colorectal Cancer

Project members

Irving J. Bigio, Boston University

Satish K. Singh, Boston University Medical School


The project demonstrates the benefits of elastic scattering spectroscopy (ESS) as a pre-screening tool for colorectal cancer (CRC) at the primary-care physician (PCP) level. An optical measurement of the rectal/sigmoid mucosa that reliably predicts the presence of proximal adenomatous polyps, would dramatically alter clinical CRC screening and prevention paradigms. ESS offers the advantages of simplicity, low-cost and clinical friendliness, and enables the opportunity dramatically improve crc screeing in the PCP office. The goal is to demonstrate improvements in the screening and prevention of CRC compared to current standard practices. The potential impact on the health care system is profound, including greater CRC screening compliance and access, while lowering the overall cost burden.