{"id":1028,"date":"2018-09-05T14:11:09","date_gmt":"2018-09-05T18:11:09","guid":{"rendered":"https:\/\/www.bu.edu\/cell-met\/?page_id=1028"},"modified":"2025-10-03T14:01:32","modified_gmt":"2025-10-03T18:01:32","slug":"research-publications","status":"publish","type":"page","link":"https:\/\/www.bu.edu\/cell-met\/research\/research-publications\/","title":{"rendered":"Research Publications"},"content":{"rendered":"<p>CELL-MET faculty, trainees, and staff have published over 100 articles. Where available, publicly accessible links are provided below.<\/p>\n<p>[\/collapsible]<\/p>\n<div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h2 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">October 2023 to September 2024: Project Year 7<\/h2><div class=\"bu_collapsible_section\" style=\"display: none;\"><\/p>\n<p>Bae, H., Men, J., &#038; Mondisa, J. (2024). Education and Outreach Program Managers\u2019 Approaches to Engaging with Engineering Students in Summer Research Programs in the US. Education Sciences, 14(12), 1371.<\/p>\n<p><\/div>\n<\/div>\n\n<div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h2 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">October 2022 to September 2023: Project Year 6<\/h2><div class=\"bu_collapsible_section\" style=\"display: none;\"><\/p>\n<p>Agarwal, A., John, D., Lou, L., Rodrigues de Oliveira, N., Sahani, R., &#038; Sukumaran, A. K. (2023). Localized Nanoindentation Paradigm for Revealing Sutured Tissue Interface Mechanics and Integrity. ACS Applied Bio Materials, 6(2), 908-918.<\/p>\n<p>Baker, B. M., Bluem, A. S., DePalma, S., Jewett, M., Stis, A., &#038; Xi, S. (2022). Microfabricated Anisotropic Tissue Bundles for the Production of 3D Cardiac Tissue at Scale. Circulation, 146(Suppl_1), A15845-A15845.<\/p>\n<p>Haber, A. and Bifano, T. (2022). Dual-update data-driven control of deformable mirrors using Walsh basis functions. JOSA A, 39(3), pp.459-469.<\/p>\n<p>Imboden, M., Chen, S., Gudozhnik, O., Pollock, C., Javor, J., Bishop, D., &#8230; &#038; Rosset, S. (2022). The integration of optical stimulation in a mechanically dynamic cell culture substrate. Frontiers in Bioengineering and Biotechnology, 10, 934756.<\/p>\n<p>Javor, J., Imboden, M., Stange, A., Yao, Z., Campbell, D.K. and Bishop, D.J. (2022). Zeptometer Metrology Using the Casimir Effect. Journal of Low Temperature Physics, pp.1-13.<\/p>\n<p>Javor, J., Yao, Z., Barrett, L., Imboden, M., Apte, S., Giannetta, R. W., &#8230; &#038; Bishop, D. J. (2023). Modal engineering of electromagnetic circuits to achieve rapid settling times. Review of Scientific Instruments, 94(1), 014708.<\/p>\n<p>Jewett, M. E., Bluem, A. S., Xi, S. S., Zhang, Z., Hiraki, H. L., Wojasi\u0144ski, M., &#038; Baker, B. M. (2023). Rapid Magnetically Directed Assembly of Pre\u2010Patterned Capillary\u2010Scale Microvessels. Advanced Functional Materials, 2203715.<\/p>\n<p>Jewett, M., Bluem, A., Xi, S., DePalma, S., Stis, A., &#038; Baker, B. (2022). Microfabricated Anisotropic Tissue Bundles for the Production of 3D Cardiac Tissue at Scale. Circulation, 146(Suppl_1), A15845-A15845.<\/p>\n<p>Kalkunte, N., McGowen, L., Qasim, M., &#038; Borrego, M. (2022, August). Conducting a Diversity, Equity, and Inclusion Climate Survey of Engineering within a Large Texas University. In 2022 ASEE Annual Conference &#038; Exposition.<\/p>\n<p>Lenzi, E., Jimenez de Aberasturi, D., Henriksen-Lacey, M., Pi\u00f1eiro, P., Muniz, A.J., Lahann, J. and Liz-Marz\u00e1n, L.M., 2022. SERS and Fluorescence-Active Multimodal Tessellated Scaffolds for Three-Dimensional Bioimaging. ACS applied materials &#038; interfaces.<\/p>\n<p>Lou, L., Paolino, L., &#038; Agarwal, A. (2023). Bridging the Gap in Ashby\u2019s Map for Soft Material Properties for Tissue Engineering. ACS Applied Materials &#038; Interfaces.<\/p>\n<p>Lou, L., Agarwal, A., He, J., &#038; Rubfiaro, A. S. (2023). Understanding Spatiotemporal Mechanical Behavior, Viscoelasticity, and Functions of Stem Cell-Derived Cardiomyocytes. Nanoscale.<\/p>\n<p>Ma, M. S., Bifano, T. G., Agarwal, A., Chen, C. S., Lou, L., &#038; Sundaram, S. (2023). High throughput screening system for engineered cardiac tissues. Frontiers in Bioengineering and Biotechnology, 11, 1177688.<\/p>\n<p>Margara, F., Psaras, Y., Wang, Z. J., Schmid, M., Doste, R., Garfinkel, A. C., \u2026 &#038; Bueno-Orovio, A. (2022). Mechanism based therapies enable  ersonalized treatment of hypertrophic cardiomyopathy. Scientific Reports, 12(1), 22501.<\/p>\n<p>Margara, F., Psaras, Y., Wang, Z.J., Schmid, M., Doste, R., Garfinkel, A., Repetti, G.G., Seidman, J., Seidman, C., Rodriguez, B. and Toepfer, C.N., 2022. Human iPSC-CMs and in-silico technologies define mechanisms and accelerate targeted pharmacogenetics in hypertrophic cardiomyopathy. bioRxiv.<\/p>\n<p>Mohammadzadeh, S., &#038; Lejeune, E. (2023). SarcGraph: A Python package for analyzing the contractile behavior of pluripotent stem cell-derived cardiomyocytes. Journal of Open Source Software, 8(85), 5322.<\/p>\n<p>Moore, J., Ewoldt, J., Venturini, G., Pereira, A. C., Padilha, K., Lawton, M., &#8230; &#038; Emili, A. (2023). Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation\u2013Contraction Coupling. International journal of molecular sciences, 24(5), 4724.<\/p>\n<p>Nautiyal, P., Agarwal, A., Bacca, N., Thomas, T., Wiedorn, V., &#038; White, A. (2022). Unraveling the Mechanisms Governing Anisotropy in Accordion\u2010Shaped Honeycomb Microlattice Fabricated by Two\u2010Photon Polymerization. Advanced Engineering Materials, 24(5), 2101190.<\/p>\n<p>Reichart, D., Lindberg, E. L., Maatz, H., Miranda, A. M., Viveiros, A., Shvetsov, N., \u2026 &#038; Seidman, C. E. (2022). Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies. Science, 377(6606), eabo1984.<\/p>\n<p>Ronaldson-Bouchard, K., Teles, D., Yeager, K., Tavakol, D.N., Zhao, Y., Chramiec, A., Tagore, S., Summers, M., Stylianos, S., Tamargo, M. and Lee, B.M., 2022. A multi-organ chip with matured tissue niches linked by vascular flow. Nature Biomedical Engineering, 6(4), pp<\/p>\n<p><\/div>\n<\/div>\n\n<div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h2 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">October 2021 to September 2022: Project Year 5<\/h2><div class=\"bu_collapsible_section\" style=\"display: none;\"><\/p>\n<p>Ahrens, J., Uzel, S., Skylar\u2010Scott, M., Mata, M., Lu, A., Kroll, K. and Lewis, J.A., 2022. Programming Cellular Alignment in Engineered Cardiac Tissue via Bioprinting Anisotropic Organ Building Blocks. Advanced Materials, p.2200217. DOI: <a href=\"https:\/\/doi.org\/10.1002\/adma.202200217\">https:\/\/doi.org\/10.1002\/adma.202200217<\/a><\/p>\n<p>Bifano, T., Chen, C., Li, H., Sundaram, S. and Hu, R., 2021. Dynamic Control of Contractile Force in Engineered Heart Tissue. DOI: <a href=\"https:\/\/doi.org\/10.36227\/techrxiv.15025236.v1\">https:\/\/doi.org\/10.36227\/techrxiv.15025236.v1<\/a><\/p>\n<p>Davidson, C.D., DePalma, S.J., Wang, W.Y., Kamen, J.L., Jayco, D.K.P. and Baker, B.M., 2021. Mechanical intercellular communication via matrix-borne cell force transmission during vascular network formation. bioRxiv. DOI: <a href=\"https:\/\/doi.org\/10.1101\/2021.08.17.456669\">https:\/\/doi.org\/10.1101\/2021.08.17.456669<\/a><\/p>\n<p>Javor, J., Imboden, M., Stange, A., Yao, Z., Campbell, D.K. and Bishop, D.J., 2022. Zeptometer Metrology Using the Casimir Effect. Journal of Low Temperature Physics, pp.1-13. DOI: <a href=\"https:\/\/doi.org\/10.1007\/s10909-021-02650-3\">https:\/\/doi.org\/10.1007\/s10909-021-02650-3<\/a><\/p>\n<p>Haber, A. and Bifano, T., 2021. General approach to precise deformable mirror control. <em>Optics Express,<\/em> 29(21), pp.33741-33759. DOI: <a href=\"https:\/\/doi.org\/10.1364\/OE.439306\">https:\/\/doi.org\/10.1364\/OE.439306<\/a><\/p>\n<p>Lock, R., Al Asafen, H., Fleischer, S., Tamargo, M., Zhao, Y., Radisic, M. and Vunjak-Novakovic, G., 2021. A framework for developing sex-specific engineered heart models. Nature Reviews Materials, pp.1-19. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41578-021-00381-1\">https:\/\/doi.org\/10.1038\/s41578-021-00381-1<\/a><\/p>\n<p>Lou, L., Lopez, K.O., Nautiyal, P. and Agarwal, A., 2021. Integrated Perspective of Scaffold Designing and Multiscale Mechanics in Cardiac Bioengineering. <em>Advanced NanoBiomed Research,<\/em> p.2100075. DOI: <a href=\"https:\/\/doi.org\/10.1002\/anbr.202100075\">https:\/\/doi.org\/10.1002\/anbr.202100075<\/a><\/p>\n<p>Nautiyal, P., Wiedorn, V., Thomas, T., Bacca, N., White, A. and Agarwal, A., Unraveling Mechanisms Governing Anisotropy in Accordion\u2010shaped Honeycomb Microlattice Fabricated by Two\u2010Photon Polymerization. Advanced Engineering Materials. DOI: <a href=\"https:\/\/doi.org\/10.1002\/adem.202101190\">https:\/\/doi.org\/10.1002\/adem.202101190<\/a><\/p>\n<p>Pandey, P., Rubfiaro, A.S., Khatri, S. and He, J., 2021. Development of multifunctional nanopipettes for controlled intracellular delivery and single-entity detection. <em>Faraday Discussions.<\/em> DOI: <a href=\"https:\/\/doi.org\/10.1039\/D1FD00057H\">https:\/\/doi.org\/10.1039\/D1FD00057H<\/a><\/p>\n<p>Rodr\u00edguez, C., Chen, A., Rivera, J.A., Mohr, M.A., Liang, Y., Natan, R.G., Sun, W., Milkie, D.E., Bifano, T.G., Chen, X. and Ji, N., 2021. An adaptive optics module for deep tissue multiphoton imaging in vivo. <em>Nature Methods,<\/em> 18(10), pp.1259-1264. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41592-021-01279-0\">https:\/\/doi.org\/10.1038\/s41592-021-01279-0<\/a><\/p>\n<p>Tsan, Y.C., DePalma, S.J., Zhao, Y.T., Capilnasiu, A., Wu, Y.W., Elder, B., Panse, I., Ufford, K., Matera, D.L., Friedline, S. and O\u2019Leary, T.S., 2021. Physiologic biomechanics enhance reproducible contractile development in a stem cell derived cardiac muscle platform. <em>Nature Communications,<\/em> 12(1), pp.1-16. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41467-021-26496-1\">https:\/\/doi.org\/10.1038\/s41467-021-26496-1<\/a><\/p>\n<p>Zhang, K., Cloonan, P.E., Sundaram, S., Liu, F., Das, S.L., Ewoldt, J.K., Bays, J.L., Tomp, S., Toepfer, C.N., Marsiglia, J.D. and Gorham, J., 2021. Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization. Science advances, 7(42), p.eabh3995. DOI: <a href=\"https:\/\/doi.org\/10.1126\/sciadv.abh3995\">https:\/\/doi.org\/10.1126\/sciadv.abh3995<\/a><\/p>\n<p>Zhao, B., Zhang, K., Chen, C.S. and Lejeune, E., 2021. Sarc-Graph: Automated segmentation, tracking, and analysis of sarcomeres in hiPSC-derived cardiomyocytes. <em>arXiv preprint arXiv<\/em>:2102.02412. DOI: <a href=\"https:\/\/doi.org\/10.1371\/journal.pcbi.1009443\">https:\/\/doi.org\/10.1371\/journal.pcbi.1009443<\/a><\/p>\n<p>&nbsp;<\/div>\n<\/div>\n\n<div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h2 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">October 2020 to September 2021: Project Year 4<\/h2><div class=\"bu_collapsible_section\" style=\"display: none;\"><strong><u>Peer-Reviewed Articles<\/u><\/strong><br \/>\nAgarwal, R., Paulo, J.A., Toepfer, C.N., Ewoldt, J.K., Sundaram, S., Chopra, A., Zhang, Q., Gorham, J., DePalma, S.R., Chen, C.S. and Gygi, S.P., 2021. Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation. <em>Circulation Research<\/em>, <em>129<\/em>(7), pp.751-766. DOI: <a href=\"https:\/\/doi.org\/10.1161\/CIRCRESAHA.120.317076\">https:\/\/doi.org\/10.1161\/CIRCRESAHA.120.317076<\/a><\/p>\n<p>Barrett, L. K., Imboden, M., Javor, J., Campbell, D. K., &amp; Bishop, D. J. (2021). Feedforward Control Algorithms for MEMS Galvos and Scanners. <em>Journal of Microelectromechanical Systems.<\/em> DOI: <a href=\"https:\/\/doi.org\/10.1109\/JMEMS.2021.3074301\">https:\/\/doi.org\/10.1109\/JMEMS.2021.3074301<\/a><\/p>\n<p>Barrett, L.K., Lally, R.W., Fuhr, N.E., Stange, A. and Bishop, D.J., 2020. A Chip-Scale, Low Cost PVD System. Journal of Microelectromechanical Systems, 29(6), pp.1547-1555. DOI: <a href=\"https:\/\/doi.org\/10.1109\/JMEMS.2020.3026533\">https:\/\/doi.org\/10.1109\/JMEMS.2020.3026533<\/a><\/p>\n<p>Chramiec, A., Teles, D., Yeager, K., Marturano-Kruik, A., Pak, J., Chen, T., Hao, L., Wang, M., Lock, R., Tavakol, D. N., Lee, M. B., Kim, J., Ronaldson-Bouchard, K., and Vunjak-Novakovic, G., 2020. Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety. <em>Lab on a chip,<\/em> 20(23), 4357\u20134372. DOI: <a href=\"https:\/\/doi.org\/10.1039\/d0lc00424c\">https:\/\/doi.org\/10.1039\/d0lc00424c<\/a><\/p>\n<p>DePalma, S.J., Davidson, C.D., Stis, A.E., Helms, A.S. and Baker, B.M., 2021. Microenvironmental determinants of organized iPSC-cardiomyocyte tissues on synthetic fibrous matrices. <em>Biomaterials Science,<\/em> 9, pp.93-107. DOI: <a href=\"https:\/\/doi.org\/10.1039\/D0BM01247E\">https:\/\/doi.org\/10.1039\/D0BM01247E<\/a><\/p>\n<p>Guo, J., Yan, X., Xu, M., Ghimire, G., Pan, X., &amp; He, J. (2021). Effective Electrochemical Modulation of SERS Intensity Assisted by Core\u2013Shell Nanoparticles. <em>Analytical Chemistry,<\/em> 93(10), 4441-4448. DOI: <a href=\"https:\/\/doi.org\/10.1021\/acs.analchem.0c04398\">https:\/\/doi.org\/10.1021\/acs.analchem.0c04398<\/a><\/p>\n<p>Horowitz, J. A., Zhong, X., DePalma, S. J., Ward Rashidi, M. R., Baker, B. M., Lahann, J., &amp; Forrest, S. R. (2021). Printable Organic Electronic Materials for Precisely Positioned Cell Attachment. <em>Langmuir,<\/em> 37(5), 1874-1881. DOI: <a href=\"https:\/\/doi.org\/10.1021\/acs.langmuir.0c03319\">https:\/\/doi.org\/10.1021\/acs.langmuir.0c03319<\/a><\/p>\n<p>Javor, J., Sundaram, S., Chen, C.S. and Bishop, D.J., 2020. A microtissue platform to simultaneously actuate and detect mechanical forces via non-contact magnetic approach. Journal of Microelectromechanical Systems, 30(1), pp.96-104. DOI: <a href=\"https:\/\/doi.org\/10.1109\/JMEMS.2020.3036978\">https:\/\/doi.org\/10.1109\/JMEMS.2020.3036978<\/a><\/p>\n<p>Javor J, Ewoldt JK, Cloonan PE, Chopra A, Luu RJ, Freychet G, Zhernenkov M, Ludwig K, Seidman JG, Seidman CE and Chen CS., 2021, January. Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41378-020-00234-x\">https:\/\/doi.org\/10.1038\/s41378-020-00234-x<\/a><\/p>\n<p>Javor, J., Sundaram, S., Chen, C. and Bishop, D.J., 2020, January. Controlled strain of cardiac microtissue via magnetic actuation. In 2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS) (pp. 452-455). IEEE. DOI: <a href=\"https:\/\/doi.org\/10.1109\/MEMS46641.2020.9056152\">https:\/\/doi.org\/10.1109\/MEMS46641.2020.9056152<\/a><\/p>\n<p>Javor, J., Stange, A., Pollock, C., Fuhr, N. and Bishop, D.J., 2020. 100 pT\/cm single-point MEMS magnetic gradiometer from a commercial accelerometer. Microsystems &amp; nanoengineering, 6(1), pp.1-13. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41378-020-0173-z\">https:\/\/doi.org\/10.1038\/s41378-020-0173-z<\/a><\/p>\n<p>Javor, J., Yao, Z., Imboden, M., Campbell, D.K. and Bishop, D.J., 2021. Analysis of a Casimir-driven parametric amplifier with resilience to Casimir pull-in for MEMS single-point magnetic gradiometry. <em>Microsystems &amp; nanoengineering<\/em>, <em>7<\/em>(1), pp.1-11. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41378-021-00289-4\">https:\/\/doi.org\/10.1038\/s41378-021-00289-4<\/a><\/p>\n<p>Jayne, R.K., Karakan, M.\u00c7., Zhang, K., Pierce, N., Michas, C., Bishop, D.J., Chen, C.S., Ekinci, K.L. and White, A.E., 2021. Direct laser writing for cardiac tissue engineering: a microfluidic heart on a chip with integrated transducers. <em>Lab on a Chip<\/em>, <em>21<\/em>(9), pp.1724-1737. DOI: <a href=\"https:\/\/doi.org\/10.1039\/D0LC01078B\">https:\/\/doi.org\/10.1039\/D0LC01078B<\/a><\/p>\n<p>Kong, N., Guo, J., Chang, S., Pan, J., Wang, J., Zhou, J., Liu, J., Zhou, H., Pfeffer, F.M., Liu, J. and Barrow, C.J., 2021. Direct Observation of Amide Bond Formation in a Plasmonic Nanocavity Triggered by Single Nanoparticle Collisions. <em>Journal of the American Chemical Society,<\/em> 143(26), pp.9781-9790. DOI: <a href=\"https:\/\/doi.org\/10.1021\/jacs.1c02426\">https:\/\/doi.org\/10.1021\/jacs.1c02426<\/a><\/p>\n<p>Lejeune, E. and Zhao, B., 2020. Exploring the potential of transfer learning for metamodels of heterogeneous material deformation. <em>Journal of the Mechanical Behavior of Biomedical Materials,<\/em> p.104276. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.jmbbm.2020.104276\">https:\/\/doi.org\/10.1016\/j.jmbbm.2020.104276<\/a><\/p>\n<p>Liu, B., Wang, B., Zhang, X., Lock, R., Nash, T. and Vunjak-Novakovic, G., 2021. Cell type\u2013specific microRNA therapies for myocardial infarction. <em>Science Translational Medicine,<\/em> 13(580). DOI: <a href=\"https:\/\/doi.org\/10.1126\/scitranslmed.abd0914\">https:\/\/doi.org\/10.1126\/scitranslmed.abd0914<\/a><\/p>\n<p>Lou, L., Rubfiaro, A.S., He, J. and Agarwal, A., 2021. Effect of Electrical Stimulation on Spontaneously Beating Dynamics of Cardiac Tissues: An Analysis Using Digital Image Correlation. <em>Advanced Materials Technologies,<\/em> p.2100669. DOI: <a href=\"https:\/\/doi.org\/10.1002\/admt.202100669\">https:\/\/doi.org\/10.1002\/admt.202100669<\/a><\/p>\n<p>Moon, S., Jones, M.S., Seo, E., Lee, J., Lahann, L., Jordahl, J.H., Lee, K.J. and Lahann, J., 2021. 3D jet writing of mechanically actuated tandem scaffolds. <em>Science Advances<\/em>, <em>7<\/em>(16), p.eabf5289. DOI: <a href=\"https:\/\/doi.org\/10.1126\/sciadv.abf5289\">https:\/\/doi.org\/10.1126\/sciadv.abf5289<\/a><\/p>\n<p>Mozneb, M., Mirtaheri, E., Sanabria, A.O. and Li, C.Z., 2020. Bioelectronic properties of DNA, protein, cells and their applications for diagnostic medical devices. Biosensors and Bioelectronics, 167, p.112441. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.bios.2020.112441\">https:\/\/doi.org\/10.1016\/j.bios.2020.112441<\/a><\/p>\n<p>Nautiyal, P., Zhang, C., Boesl, B. and Agarwal, A., 2021. Interfacial deformation and failure mechanisms at the single-splat length scale revealed in-situ by indentation of cold sprayed aluminum microparticles. <em>Materials Science and Engineering: A<\/em>, p.141828. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.msea.2021.141828\">https:\/\/doi.org\/10.1016\/j.msea.2021.141828<\/a><\/p>\n<p>Neale, D.B., Mu\u00f1iz, A.J., Jones, M.S., Kim, D.H., Buschhaus, J.M., Humphries, B.A., Wang, W.Y., Baker, B.M., Raymond, J.E., Solorio, L. and Luker, G.D., 2021. Aligned Networks of Engineered Fibrillar Fibronectin Guide Cellular Orientation and Motility. <em>Small Structures<\/em>, p.2000137. DOI: <a href=\"https:\/\/doi.org\/10.1002\/sstr.202000137\">https:\/\/doi.org\/10.1002\/sstr.202000137<\/a><\/p>\n<p>Orikasa, K., Bacca, N., &amp; Agarwal, A. (2021). Meso\/macro-scale ultra-soft materials\u2019 mechanical property evaluation device and testbed. <em>Review of Scientific Instruments,<\/em> 92(7), 073904. DOI: <a href=\"https:\/\/doi.org\/10.1063\/5.0046282\">https:\/\/doi.org\/10.1063\/5.0046282<\/a><\/p>\n<p>P\u00e9rez-Morelo, D., Stange, A., Lally, R.W., Barrett, L.K., Imboden, M., Som, A., Campbell, D.K., Aksyuk, V.A. and Bishop, D.J., 2020. A system for probing Casimir energy corrections to the condensation energy. Microsystems &amp; nanoengineering, 6(1), pp.1-12. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41378-020-00221-2\">https:\/\/doi.org\/10.1038\/s41378-020-00221-2<\/a><\/p>\n<p>Pollock, C., Javor, J., Stange, A., Barrett, L.K. and Bishop, D.J., 2019. Extreme angle, tip-tilt MEMS micromirror enabling full hemispheric, quasi-static optical coverage. Optics express, 27(11), pp.15318-15326. DOI: <a href=\"https:\/\/doi.org\/10.1364\/OE.27.015318\">https:\/\/doi.org\/10.1364\/OE.27.015318<\/a><\/p>\n<p>Psaras, Y., Margara, F., Cicconet, M., Sparrow, A. J., Repetti, G., Schmid, M., \u2026 &amp; Toepfer, C. N. (2021). CalTrack: High Throughput Automated Calcium Transient Analysis in Cardiomyocytes. <em>Circulation Research.<\/em> DOI: <a href=\"https:\/\/doi.org\/10.1161\/CIRCRESAHA.121.318868\">https:\/\/doi.org\/10.1161\/CIRCRESAHA.121.318868<\/a><\/p>\n<p>Rubfiaro, A.S., Tsegay, P.S., Lai, Y., Cabello, E., Shaver, M., Hutcheson, J., Liu, Y. and He, J., 2021. Scanning Ion Conductance Microscopy Study Reveals the Disruption of the Integrity of the Human Cell Membrane Structure by Oxidative DNA Damage. <em>ACS Applied Bio Materials<\/em>, <em>4<\/em>(2), pp.1632-1639. DOI: <a href=\"https:\/\/doi.org\/10.1021\/acsabm.0c01461\">https:\/\/doi.org\/10.1021\/acsabm.0c01461<\/a><\/p>\n<p>Sharma, A., Wasson, L.K., Willcox, J.A., Morton, S.U., Gorham, J.M., DeLaughter, D.M., Neyazi, M., Schmid, M., Agarwal, R., Jang, M.Y. and Toepfer, C.N., 2020. GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm. <em>Elife,<\/em> 9, p.e53278. DOI: <a href=\"https:\/\/doi.org\/10.7554\/eLife.53278\">https:\/\/doi.org\/10.7554\/eLife.53278<\/a><\/p>\n<p>Song, J., Korunes\u2010Miller, J., Banerji, R., Wu, Y., Fazeli, S., Zheng, H., Orr, B., Morgan, E., Andry, C., Henderson, J. and Miller, N.S., 2021. On\u2010Site, On\u2010Demand 3D\u2010Printed Nasopharyngeal Swabs to Improve the Access of Coronavirus Disease\u201019 Testing. <em>Global Challenges<\/em>, <em>5<\/em>(11), p.2100039. DOI: <a href=\"https:\/\/doi.org\/10.1002\/gch2.202100039\">https:\/\/doi.org\/10.1002\/gch2.202100039<\/a><\/p>\n<p>Song, J., Michas, C., Chen, C. S., White, A. E., &amp; Grinstaff, M. W. (2021). Controlled Cell Alignment Using Two\u2010Photon Direct Laser Writing\u2010Patterned Hydrogels in 2D and 3D. <em>Macromolecular Bioscience,<\/em> 21(5), 2100051. DOI: <a href=\"https:\/\/doi.org\/10.1002\/mabi.202100051\">https:\/\/doi.org\/10.1002\/mabi.202100051<\/a><\/p>\n<p>Tsang, J. M., Gritton, H. J., Das, S. L., Weber, T. D., Chen, C. S., Han, X., &amp; Mertz, J. (2021). Fast, multiplane line-scan confocal microscopy using axially distributed slits. <em>Biomedical optics express,<\/em> 12(3), 1339-1350. DOI: <a href=\"https:\/\/doi.org\/10.1364\/BOE.417286\">https:\/\/doi.org\/10.1364\/BOE.417286<\/a><\/p>\n<p>Ward, T., Tai, W., Morton, S., Impens, F., Van Damme, P., Van Haver, D., Timmerman, E., Venturini, G., Zhang, K., Jang, M.Y. and Willcox, J.A., 2021. Mechanisms of congenital heart disease caused by NAA15 haploinsufficiency. Circulation research, 128(8), pp.1156-1169. DOI: <a href=\"https:\/\/doi.org\/10.1161\/CIRCRESAHA.120.316966\">https:\/\/doi.org\/10.1161\/CIRCRESAHA.120.316966<\/a><\/p>\n<p>&nbsp;<br \/>\n<\/div>\n<\/div>\n\n<div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h2 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">October 2019 to September 2020: Project Year 3<\/h2><div class=\"bu_collapsible_section\" style=\"display: none;\"><strong><u>Peer-Reviewed Articles<\/u><\/strong><\/p>\n<p>Beaulieu, D.R., Davison, I.G., K\u0131l\u0131\u00e7, K., Bifano, T.G. and Mertz, J., 2020. Simultaneous multiplane imaging with reverberation two-photon microscopy. <em>Nature methods,<\/em> 17(3), pp.283-286. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41592-019-0728-9\">https:\/\/doi.org\/10.1038\/s41592-019-0728-9<\/a><\/p>\n<p>Chen, F., Panday, N., Li, X., Ma, T., Guo, J., Wang, X., Kos, L., Hu, K., Gu, N. and He, J., 2020. Simultaneous mapping of nanoscale topography and surface potential of charged surfaces by scanning ion conductance microscopy. <em>Nanoscale,<\/em> 12(40), pp.20737-20748. DOI: <a href=\"https:\/\/doi.org\/10.1039\/D0NR04555A\">https:\/\/doi.org\/10.1039\/D0NR04555A<\/a><\/p>\n<p>Christopher, J.W., Vutukuru, M., Lloyd, D., Bunch, J.S., Goldberg, B.B., Bishop, D.J. and Swan, A.K., 2019. Monolayer MoS 2 strained to 1.3% with a microelectromechanical system. Journal of <em>Microelectromechanical Systems,<\/em> 28(2), pp.254-263. DOI: <a href=\"https:\/\/doi.org\/10.1109\/JMEMS.2018.2877983\">https:\/\/doi.org\/10.1109\/JMEMS.2018.2877983<\/a><\/p>\n<p>Davidson, C.D., Jayco, D.K.P., Matera, D.L., DePalma, S.J., Hiraki, H.L., Wang, W.Y. and Baker, B.M., 2020. Myofibroblast activation in synthetic fibrous matrices composed of dextran vinyl sulfone. <em>Acta biomaterialia,<\/em> 105, pp.78-86. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.actbio.2020.01.009\">https:\/\/doi.org\/10.1016\/j.actbio.2020.01.009<\/a><\/p>\n<p>Fine, B. and Vunjak-Novakovic, G., 2020. Heart regeneration in mouse and human: a bioengineering perspective. <em>Current opinion in physiology,<\/em> 14, pp.56-63. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.cophys.2020.01.004\">https:\/\/doi.org\/10.1016\/j.cophys.2020.01.004<\/a><\/p>\n<p>Fleischer, S., Tavakol, D. N., and Vunjak-Novakovic, G., 2020. From Arteries to Capillaries: Approaches to Engineering Human Vasculature. <em>Adv. Funct. Mater.<\/em> (30)1910811. DOI: <a href=\"https:\/\/doi.org\/10.1002\/adfm.201910811\">https:\/\/doi.org\/10.1002\/adfm.201910811<\/a><\/p>\n<p>Guo, J., Rubfiaro, A.S., Lai, Y., Moscoso, J., Chen, F., Liu, Y., Wang, X. and He, J., 2020. Dynamic single-cell intracellular pH sensing using a SERS-active nanopipette. <em>Analyst,<\/em> 145(14), pp.4852-4859. DOI: <a href=\"https:\/\/doi.org\/10.1039\/D0AN00838A\">https:\/\/doi.org\/10.1039\/D0AN00838A<\/a><\/p>\n<p>Litvi\u0148ukov\u00e1, M., Talavera-L\u00f3pez, C., Maatz, H., Reichart, D., Worth, C.L., Lindberg, E.L., Kanda, M., Polanski, K., Heinig, M., Lee, M., Nadelmann, E.R., Roberts, K., Tuck, L., Fasouli, E.S., DeLaughter, D.M., McDonnough, B., Wakimoto, H., Gorham, J., Samari, S., Mahbubani, K.T., Saeb-Parsy, K., Patone, G., Boyle, J.J., Zhang, H., Zhang, H., Viveiros, A., Oudit, G.Y., Bayraktar, O.A., Seidman, C.E., Noseda, M., Hubner, N. and Teichmann, S.A., 2020. Cells of the adult human heart. <em>Nature,<\/em> 588(7838), pp.466-472. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41586-020-2797-4\">https:\/\/doi.org\/10.1038\/s41586-020-2797-4<\/a><\/p>\n<p>Mozneb, M., Mirza, A. M., &amp; Li, C. Z., 2019. Non-Invasive Plasmonic Based Real Time Characterization of Cardiac Drugs on Cardiomyocytes Functional Behavior.\u00a0<em>Analytical Chemistry.<\/em> DOI: <a href=\"https:\/\/doi.org\/10.1021\/acs.analchem.9b04956\">https:\/\/doi.org\/10.1021\/acs.analchem.9b04956<\/a><\/p>\n<p>Pandey, P., Garcia, J., Guo, J., Wang, X., Yang, D. and He, J., 2019. Differentiation of metallic and dielectric nanoparticles in solution by single-nanoparticle collision events at the nanoelectrode. <em>Nanotechnology,<\/em> 31(1), p.015503. DOI: <a href=\"https:\/\/doi.org\/10.1088\/1361-6528\/ab4445\">https:\/\/doi.org\/10.1088\/1361-6528\/ab4445<\/a><\/p>\n<p>Pandey, P., Ghimire, G., Garcia, J., Rubfiaro, A., Wang, X., Tomitaka, A., Nair, M., Kaushik, A. and He, J., 2020. Single-entity approach to investigate surface charge enhancement in magnetoelectric nanoparticles induced by AC magnetic field stimulation. <em>ACS Sensors.<\/em> DOI: <a href=\"https:\/\/doi.org\/10.1021\/acssensors.0c00664\">https:\/\/doi.org\/10.1021\/acssensors.0c00664<\/a><\/p>\n<p>Pollock, C., Pardo, F., Imboden, M. and Bishop, D.J., 2020. Open loop control theory algorithms for high-speed 3D MEMS optical switches. <em>Optics Express,<\/em> 28(2), pp.2010-2019. DOI: <a href=\"https:\/\/doi.org\/10.1364\/OE.367554\">https:\/\/doi.org\/10.1364\/OE.367554<\/a><\/p>\n<p>Sarwar, M., Leichner, J., Naja, G.M. and Li, C.Z., 2019. Smart-phone, paper-based fluorescent sensor for ultra-low inorganic phosphate detection in environmental samples. M<em>icrosystems &amp; Nanoengineering,<\/em> 5(1), pp.1-10. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41378-019-0096-8\">https:\/\/doi.org\/10.1038\/s41378-019-0096-8<\/a><\/p>\n<p>Shroff, S.N., Das, S.L., Tseng, H.A., Noueihed, J., Fernandez, F., White, J.A., Chen, C.S. and Han, X., 2020. Voltage Imaging of Cardiac Cells and Tissue Using the Genetically Encoded Voltage Sensor Archon1. <em>Iscience,<\/em> 23(4), p.100974. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.isci.2020.100974\">https:\/\/doi.org\/10.1016\/j.isci.2020.100974<\/a><\/p>\n<p>Song, H.H.G., Lammers, A., Sundaram, S., Rubio, L., Chen, A.X., Li, L., Eyckmans, J., Bhatia, S.N. and Chen, C.S., 2020. Transient support from fibroblasts is sufficient to drive functional vascularization in engineered tissues. <em>Advanced Functional Materials,<\/em> 30(48), p.2003777. DOI: <a href=\"https:\/\/doi.org\/10.1002\/adfm.202003777\">https:\/\/doi.org\/10.1002\/adfm.202003777<\/a><\/p>\n<p>Song, J., Michas, C., Chen, C.S., White, A.E. and Grinstaff, M.W., 2020. From Simple to Architecturally Complex Hydrogel Scaffolds for Cell and Tissue Engineering Applications: Opportunities Presented by Two-Photon Polymerization. <em>Advanced Healthcare Materials,<\/em> 9(1), p.1901217. DOI: <a href=\"https:\/\/doi.org\/10.1002\/adhm.201901217\">https:\/\/doi.org\/10.1002\/adhm.201901217<\/a><\/p>\n<p>Song, J., Michas, C., Chen, C.S., White, A.E. and Grinstaff, M.W., 2020. From Simple to Architecturally Complex Hydrogel Scaffolds for Cell and Tissue Engineering Applications: Opportunities Presented by Two\u2010Photon Polymerization. <em>Advanced Healthcare Materials,<\/em> 9(1), p.1901217. DOI: <a href=\"https:\/\/doi.org\/10.1002\/adhm.201901217\">https:\/\/doi.org\/10.1002\/adhm.201901217<\/a><\/p>\n<p>Thomas, T., Rubfiaro, A.S., Nautiyal, P., Brooks, R., Dickerson, D., He, J. and Agarwal, A., 2020. Extrusion 3D Printing of Porous Silicone Architectures for Engineering Human Cardiomyocyte-Infused Patches Mimicking Adult Heart Stiffness. <em>ACS Applied Bio Materials,<\/em> 3(9), pp.5865-5871. DOI: <a href=\"https:\/\/doi.org\/10.1021\/acsabm.0c00572\">https:\/\/doi.org\/10.1021\/acsabm.0c00572<\/a><\/p>\n<p>Toepfer, C.N., Garfinkel, A.C., Venturini, G., Wakimoto, H., Repetti, G., Alamo, L., Sharma, A., Agarwal, R., Ewoldt, J.F., Cloonan, P. and Letendre, J., 2020. Myosin sequestration regulates sarcomere function, cardiomyocyte energetics, and metabolism, informing the pathogenesis of hypertrophic cardiomyopathy. <em>Circulation,<\/em> 141(10), pp.828-842. DOI: <a href=\"https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.119.042339\">https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.119.042339<\/a><\/p>\n<p>Wagner, K.T., Nash, T.R., Liu, B., Vunjak-Novakovic, G. and Radisic, M., 2020. Extracellular Vesicles in Cardiac Regeneration: Potential Applications for Tissues-on-a-Chip. <em>Trends in Biotechnology.<\/em> DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.tibtech.2020.08.005\">https:\/\/doi.org\/10.1016\/j.tibtech.2020.08.005<\/a><\/p>\n<p><strong><u>Books, Book Chapters<\/u><\/strong><\/p>\n<p>Mozneb, M., Smothers, C., Rodriguez, P. &amp; Li, C.-Z., 2019. Electrochemical Analysis of Single Cells. In\u00a0R.N. Krishnaraj and R.K. Sani (Eds.), <em>Bioelectrochemical Interface Engineering<\/em> (pp. 55-76). Hoboken, NJ:\u00a0John Wiley &amp; Sons, Inc.\u00a0DOI: <a href=\"https:\/\/doi.org\/10.1002\/9781119611103.ch4\">https:\/\/doi.org\/10.1002\/9781119611103.ch4<\/a><\/p>\n<p>Nautiyal, P., Boesl, B. and Agarwal, A., 2020. <em>In-situ Mechanics of Materials. Springer International Publishing.<\/em> DOI: <a href=\"https:\/\/doi.org\/10.1007\/978-3-030-43320-8\">https:\/\/doi.org\/10.1007\/978-3-030-43320-8<\/a><\/p>\n<p>Zhao Y., Eng G., Li B.W., Radisic M. &amp; G. Vunjak-Novakovic, 2020. Cardiac Tissue Engineering. In Lanza, R., Langer, R., &amp; Vacanti, J. P. (Eds.). <em>Principles of Tissue Engineering 5th ed.<\/em> (Chapter 32).\u00a0San Diego, United States: Elsevier Science Publishing Co Inc. DOI: <a href=\"https:\/\/doi.org\/10.1016\/B978-0-12-818422-6.00033-2\">https:\/\/doi.org\/10.1016\/B978-0-12-818422-6.00033-2<\/a><\/div>\n<\/div>\n\n<div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h2 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">October 2018 to September 2019: Project Year 2<\/h2><div class=\"bu_collapsible_section\" style=\"display: none;\"><\/p>\n<p>Barrett, L. K., Stark, T., Reeves, J., Lally, R., Stange, A., Pollock, C., Imboden, M., &amp; Bishop, D. J. (2019). A Large Range of Motion 3D MEMS Scanner with Five Degrees of Freedom. <em>Journal of Microelectromechanical Systems,<\/em> 28(1), 170-179. DOI: <a href=\"https:\/\/doi.org\/10.1109\/JMEMS.2018.2886653\">https:\/\/doi.org\/10.1109\/JMEMS.2018.2886653<\/a><\/p>\n<p>Chen, F., Manandhar, P., Ahmed, M. S., Chang, S., Panday, N., Zhang, H., Moon, J. H., &amp; He, J. (2019). Extracellular Surface Potential Mapping by Scanning Ion Conductance Microscopy Revealed Transient Transmembrane Pore Formation Induced by Conjugated Polymer Nanoparticles. <em>Macromolecular Bioscience,<\/em> 19(2), 1800271. DOI: <a href=\"https:\/\/doi.org\/10.1002\/mabi.201800271\">https:\/\/doi.org\/10.1002\/mabi.201800271<\/a><\/p>\n<p>Chen, T., &amp; Vunjak-Novakovic, G. (2019). Human Tissue-Engineered Model of Myocardial Ischemia\u2013Reperfusion Injury. <em>Tissue Engineering Part A,<\/em> 25(9-10), 711-724. DOI: <a href=\"https:\/\/doi.org\/10.1089\/ten.tea.2018.0212\">https:\/\/doi.org\/10.1089\/ten.tea.2018.0212<\/a><\/p>\n<p>Cheng, D., Jayne, R. K., Tamborini, A., Eyckmans, J., White, A. E., &amp; Chen, C. S. (2019). Studies of 3D directed cell migration enabled by direct laser writing of curved wave topography. <em>Biofabrication,<\/em> 11(2), 021001. DOI: <a href=\"https:\/\/doi.org\/10.1088\/1758-5090\/ab047f\">https:\/\/doi.org\/10.1088\/1758-5090\/ab047f<\/a><\/p>\n<p>Kumar, R., Welle, A., Becker, F., Kopyeva, I., &amp; Lahann, J. (2018). Substrate-Independent Micropatterning of Polymer Brushes Based on Photolytic Deactivation of Chemical Vapor Deposition Based Surface-Initiated Atom-Transfer Radical Polymerization Initiator Films. <em>ACS Applied Materials &amp; Interfaces,<\/em> 10(38), 31965-31976. DOI: <a href=\"https:\/\/doi.org\/10.1021\/acsami.8b11525\">https:\/\/doi.org\/10.1021\/acsami.8b11525<\/a><\/p>\n<p>Lu, W., Jiao, Y., Gao, Y., Qiao, J., Mozneb, M., Shuang, S., Dong, D., &amp; Li, C. Z. (2018). Bright Yellow Fluorescent Carbon Dots as a Multifunctional Sensing Platform for the Label-Free Detection of Fluoroquinolones and Histidine. <em>ACS Applied Materials &amp; Interfaces,<\/em> 10(49), 42915-42924. DOI: <a href=\"https:\/\/doi.org\/10.1021\/acsami.8b16710\">https:\/\/doi.org\/10.1021\/acsami.8b16710<\/a><\/p>\n<p>Ma, T., Guo, J., Chang, S., Wang, X., Zhou, J., Liang, F., &amp; He, J. (2019). Modulating and probing the dynamic intermolecular interactions in plasmonic molecule-pair junctions. <em>Physical Chemistry Chemical Physics.<\/em> DOI: <a href=\"https:\/\/doi.org\/10.1039\/C9CP02030F\">https:\/\/doi.org\/10.1039\/C9CP02030F<\/a><\/p>\n<p>Mirtaheri, E., &amp; Li, C. Z. (2019). Wearable Biomedical Devices: State of the Art, Challenges, and Future Perspectives.\u00a0<em>The Electrochemical Society Interface<\/em>,\u00a0<em>28<\/em>(3), 71-74. <a href=\"https:\/\/doi.org\/10.1149\/2.F10193IF\">https:\/\/doi.org\/10.1149\/2.F10193IF<\/a><\/p>\n<p>Pollock, C., Barrett, L. K., del Corro, P. G., Stange, A., Bifano, T. G., &amp; Bishop, D. J. (2019). PWM as a Low Cost Method for the Analog Control of MEMS Devices. <em>Journal of Microelectromechanical Systems,<\/em> 28(2), 245-253. DOI: <a href=\"https:\/\/doi.org\/10.1109\/JMEMS.2019.2891205\">https:\/\/doi.org\/10.1109\/JMEMS.2019.2891205<\/a><\/p>\n<p>Reeves, J. B., Jayne, R. K., Barrett, L., White, A. E., &amp; Bishop, D. J. (2019). Fabrication of multi-material 3D structures by the integration of direct laser writing and MEMS stencil patterning. <em>Nanoscale,<\/em> 11(7), 3261-3267. DOI: <a href=\"https:\/\/doi.org\/10.1039\/C8NR09174A\">https:\/\/doi.org\/10.1039\/C8NR09174A<\/a><\/p>\n<p>Ronaldson-Bouchard, K., Teles, D., Yeager, K., Ma, S. P., Chen, T., Song, L. J., Morikawa, K., Wobma, H. M., Vasciaveo, A., Ruiz, E.C., Yazawa, M., &amp; Vunjak-Novakovic, G. (2019). Engineering of human cardiac muscle electromechanically matured to an adult-like phenotype. <em>Nature Protocols,<\/em> 14, 2781\u20132817. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41596-019-0189-8\">https:\/\/doi.org\/10.1038\/s41596-019-0189-8<\/a><\/p>\n<p>Sarwar, M., Rodriguez, P., &amp; Li, C. Z. (2019). Sweat-Based in Vitro Diagnostics (IVD): From Sample Collection to Point-of-Care Testing (POCT). <em>Journal of Analysis and Testing,<\/em> 3(1), 80-88. DOI: <a href=\"https:\/\/doi.org\/10.1007\/s41664-019-00097-w\">https:\/\/doi.org\/10.1007\/s41664-019-00097-w<\/a><\/p>\n<p>Skylar-Scott, M. A., Uzel, S. G., Nam, L. L., Ahrens, J. H., Truby, R. L., Damaraju, S., &amp; Lewis, J. A. (2019). Biomanufacturing of organ-specific tissues with high cellular density and embedded vascular channels. <em>Science Advances,<\/em> 5(9), eaaw2459. DOI: <a href=\"https:\/\/doi.org\/10.1126\/sciadv.aaw2459\">https:\/\/doi.org\/10.1126\/sciadv.aaw2459<\/a><\/p>\n<p>Stange, A., Imboden, M., Javor, J., Barrett, L. K., &amp; Bishop, D. J. (2019). Building a Casimir metrology platform with a commercial MEMS sensor. <em>Microsystems &amp; Nanoengineering,<\/em> 5(1), 14. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41378-019-0054-5\">https:\/\/doi.org\/10.1038\/s41378-019-0054-5<\/a><\/p>\n<p>Steier, A., Mu\u00f1iz, A., Neale, D., &amp; Lahann, J. (2019). Emerging Trends in Information\u2010Driven Engineering of Complex Biological Systems. <em>Advanced Materials,<\/em> 1806898. DOI: <a href=\"https:\/\/doi.org\/10.1002\/adma.201806898\">https:\/\/doi.org\/10.1002\/adma.201806898<\/a><\/p>\n<p>Thomas, T., Zhang, C., Nautiyal, P., Boesl, B., &amp; Agarwal, A. (2019). 3D Graphene Foam Reinforced Low-Temperature Ceramic with Multifunctional Mechanical, Electrical, and Thermal Properties. <em>Advanced Engineering Materials.<\/em> DOI: <a href=\"https:\/\/doi.org\/10.10.1002\/adem.201900085\">https:\/\/doi.org\/10.10.1002\/adem.201900085<\/a><\/p>\n<p>Toepfer, C. N., Sharma, A., Cicconet, M., Garfinkel, A. C., M\u00fccke, M., Neyazi, M. &amp; Ewoldt, J. (2019). SarcTrack: an adaptable software tool for efficient large-scale analysis of sarcomere function in hiPSC-cardiomyocytes. <em>Circulation Research,<\/em> 124(8), 1172-1183. DOI: <a href=\"https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.314505\">https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.314505<\/a><\/p>\n<p>Toepfer, C. N., Wakimoto, H., Garfinkel, A. C., McDonough, B., Liao, D., Jiang, J., Tai, A. C., Gorham, J. M., Lunde, I. G., Lun, M., Lynch 4th, T. L., McNamara, J. W., Sadayappan, S., Redwood C. S., Watkins, H. C., Seidman, J. G., &amp; Seidman, C. E. (2019). Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin. <em>Science Translational Medicine<\/em>, 11(476), eaat1199. DOI: <a href=\"https:\/\/doi.org\/10.1126\/scitranslmed.aat1199\">https:\/\/doi.org\/10.1126\/scitranslmed.aat1199<\/a><\/p>\n<p>Tong, L., Mozneb, M., Bravo, E., Ferrando, V., &amp; Li, C. Z. (2019). Whole cell analysis ranging from intercellular assay to organ on a chip. <em>TrAC Trends in Analytical Chemistry<\/em>. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.trac.2019.05.021\">https:\/\/doi.org\/10.1016\/j.trac.2019.05.021<\/a><\/p>\n<p>Venkidasubramonian, G., Kratzer, D., Trouillet, V., Zydziak, N., Franzreb, M., Barner, L., &amp; Lahann, J. (2018). Surface-initiated RAFT polymerization from vapor-based polymer coatings. <em>Polymer,<\/em> 150, 26-34. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.polymer.2018.06.073\">https:\/\/doi.org\/10.1016\/j.polymer.2018.06.073<\/a><\/p>\n<p>Vutukuru, M., Christopher, J. W., Pollock, C., Bishop, D. J., &amp; Swan, A. K. (2019). Modeling and Thermal Metrology of Thermally Isolated MEMS Electrothermal Actuators for Strain Engineering of 2D Materials in Air. <em>Journal of Microelectromechanical Systems,<\/em> 28(3), 550-557. DOI: <a href=\"https:\/\/doi.org\/10.1109\/JMEMS.2019.2902757\">https:\/\/doi.org\/10.1109\/JMEMS.2019.2902757<\/a><\/p>\n<p>Zhu, X., Sarwar, M., Zhu, J. J., Zhang, C., Kaushik, A., &amp; Li, C. Z. (2019). Using a glucose meter to quantitatively detect disease biomarkers through a universal nanozyme integrated lateral fluidic sensing platform. <em>Biosensors and Bioelectronics,<\/em> 126, 690-696. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.bios.2018.11.033\">https:\/\/doi.org\/10.1016\/j.bios.2018.11.033<\/a><\/div>\n<\/div>\n\n<div class=\"bu_collapsible_container \" aria-live=\"polite\" data-customize-animation=\"false\"><h2 class=\"bu_collapsible\" aria-expanded=\"false\"tabindex=\"0\" role=\"button\">October 2017 to September 2018: Project Year 1<\/h2><div class=\"bu_collapsible_section\" style=\"display: none;\"><\/p>\n<p>Ba, C., Tsang, J.-M., &amp; Mertz, J. (2018). Fast hyperspectral phase and amplitude imaging in scattering tissue. <em>Optics Letters<\/em>. 43, 2058. DOI: <a href=\"https:\/\/doi.org\/10.1364\/OL.43.002058\">https:\/\/doi.org\/10.1364\/OL.43.002058<\/a><\/p>\n<p>Badon, A. &amp; Mertz, J. (2018). Extended Depth of Field in Confocal Microscopy. In proceedings of <em>Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy\/Translational\/Brain\/OTS), OSA Technical Digest (Optical Society of America, 2018)<\/em>. paper BF4C.5. DOI: <a href=\"https:\/\/doi.org\/10.1364\/BRAIN.2018.BF4C.5\">https:\/\/doi.org\/10.1364\/BRAIN.2018.BF4C.5<\/a><\/p>\n<p>Chang, J., Holyoak, M., Kannell, G., Beacken, M., Imboden, M., &amp; Bishop, D. J. (2018). High Performance, Continuously Tunable Microwave Filters using MEMS Devices with Very Large, Controlled, Out-of-Plane Actuation. <em>Journal of Microelectromechanical Systems<\/em>,\u00a0<em>27<\/em>(6): 1135-1147. DOI: <a href=\"https:\/\/doi.org\/10.1109\/JMEMS.2018.2871657\">https:\/\/doi.org\/10.1109\/JMEMS.2018.2871657<\/a><\/p>\n<p>Chen, T. &amp; Vunjak-Novakovic, G. (2018). In Vitro Models of Ischemia-Reperfusion Injury. <em>Regenerative Engineering and Translational Medicine<\/em>. DOI: <a href=\"https:\/\/doi.org\/10.1007\/s40883-018-0056-0\">https:\/\/doi.org\/10.1007\/s40883-018-0056-0<\/a><\/p>\n<p>Chopra, Anant, Kutys, Matthew L., Zhang, Kehan, Polacheck, William J., Sheng, Calvin C., Luu, Rebeccah J., Eyckmans, Jeroen, Hinson, J. Travis, Seidman, Jonathan G., Seidman, Christine E.,\u00a0 Chen, Christopher S. (2018). Force Generation via \u03b2-Cardiac Myosin, Titin, and \u03b1-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions. <em>Developmental Cell,<\/em> 44(1). <a href=\"https:\/\/doi.org\/10.1016\/j.devcel.2017.12.012\">https:\/\/doi.org\/10.1016\/j.devcel.2017.12.012<\/a><\/p>\n<p>Christopher, J.W., Vutukuru, M., Lloyd, D., Bunch, J.S., Goldberg, B.B., Bishop, D.J., Swan, A.K. (2019). Monolayer MoS2 Strained to 1.3% With a Microelectromechanical System, <em>Journal of Microelectromechanical Systems<\/em> 28(2): 254-263. DOI: <a href=\"https:\/\/doi.org\/10.1109\/JMEMS.2018.2877983\">https:\/\/doi.org\/10.1109\/JMEMS.2018.2877983<\/a><\/p>\n<p>Del Corro, P.G., Imboden, M., P\u00e9rez, D. J., Bishop, D. J., &amp; Pastoriza, H. (2018). Single ended capacitive self-sensing system for comb drives driven XY nanopositioners. <em>Sensors and Actuators A: Physical<\/em>, 271(C). DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.sna.2017.11.021\">https:\/\/doi.org\/10.1016\/j.sna.2017.11.021<\/a><\/p>\n<p>Guo, Jing, Pan, Jie, Chang, Shuai, Wang, Xuewen, Kong, Na, Yang, Wenrong, &amp; He, Jin. (2018). Monitoring the Dynamic Process of Formation of Plasmonic Molecular Junctions during Single Nanoparticle Collisions.\u00a0<em>Small<\/em>,\u00a0<em>14<\/em>(15). DOI: <a href=\"https:\/\/doi.org\/10.1002\/smll.201704164\">https:\/\/doi.org\/10.1002\/smll.201704164<\/a><\/p>\n<p>Jay, S.M. &amp; Vunjak-Novakovic, G. (2017). Emerging Impact of Extracellular Vesicles on Tissue Engineering and Regeneration. <em>Tissue Engineering Part A. <\/em>23 (21-22), 1210-1211. <a href=\"https:\/\/doi.org\/10.1089\/ten.TEA.2017.0302\">https:\/\/doi.org\/10.1089\/ten.TEA.2017.0302<\/a><\/p>\n<p>Jayne, R.K., Stark, T.J., Reeves, J.B., Bishop, D.J., &amp; White, A.E. (2018).\u00a0 Dynamic Actuation of Soft 3D Micromechanical Structures Using Micro\u2010Electromechanical Systems (MEMS). <em>Adv. Mater. Technol. 3<\/em>, 1700293. DOI: <a href=\"https:\/\/doi.org\/10.1002\/admt.201700293\">https:\/\/doi.org\/10.1002\/admt.201700293<\/a><\/p>\n<p>Kumar, Ramya, Kratzer, Domenic, Cheng, Kenneth, Prisby, Julia, Sugai, James, Giannobile, William V., &amp; Lahann, Joerg. (2018). Carbohydrate-Based Polymer Brushes Prevent Viral Adsorption on Electrostatically Heterogeneous Interfaces.\u00a0<em>Macromolecular Rapid Communications<\/em>. DOI: <a href=\"https:\/\/doi.org\/10.1002\/marc.201800530\">https:\/\/doi.org\/10.1002\/marc.201800530<\/a><\/p>\n<p>Li, L., Eyckmans, J., &amp; Chen, C.S. (2017). Designer biomaterials for mechanobiology. <em>Nature Materials. 16<\/em> (12), 1164 to 1168. DOI: <a href=\"https:\/\/doi.org\/10.1038\/nmat5049\">https:\/\/doi.org\/10.1038\/nmat5049<\/a><\/p>\n<p>Liu, B., Lee, B.W., Nakanishi, K., Villasante, A., Williamson, R., Metz, J., Kim, J., Kanai, M., Bi, L., Brown, K., Di Paolo, G., Homma, S., Sims, P.A., Topkara, V.K., &amp; Vunjak-Novakovic, G. (2018). Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells. <em>Nature Biomedical Engineering 2<\/em> (5), 293-303. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41551-018-0229-7\">https:\/\/doi.org\/10.1038\/s41551-018-0229-7<\/a><\/p>\n<p>Nautiyal, Pranjal, Alam, Fahad, Balani, Kantesh, &amp; Agarwal, Arvind. (2018). The Role of Nanomechanics in Healthcare.\u00a0<em>Advanced Healthcare Materials<\/em>,\u00a0<em>7<\/em>(3). DOI: <a href=\"https:\/\/doi.org\/10.1002\/adhm.201700793\">https:\/\/doi.org\/10.1002\/adhm.201700793<\/a><\/p>\n<p>Nautiyal, Pranjal, Boesl, Benjamin, &amp; Agarwal, Arvind. (2018). The mechanics of energy dissipation in a three-dimensional graphene foam with macroporous architecture.\u00a0<em>Carbon<\/em>,\u00a0<em>132<\/em>(C). DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.carbon.2018.02.028\">https:\/\/doi.org\/10.1016\/j.carbon.2018.02.028<\/a><\/p>\n<p>Nautiyal, Pranjal, Mujawar, Mubarak, Boesl, Benjamin, Agarwal, Arvind. (2018) In-situ mechanics of 3D graphene foam based ultra-stiff and flexible metallic metamaterial. <em>Carbon<\/em>, 137, 502-510. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.carbon.2018.05.063\">https:\/\/doi.org\/10.1016\/j.carbon.2018.05.063<\/a><\/p>\n<p>Pandey, P., Panday, N., Chang, S., Pang, P., Garcia, J., Wang, X., Fu, Q., &amp; He, J. (2018), Probing Dynamic Events of Dielectric Nanoparticles by a Nanoelectrode\u2010Nanopore Nanopipette. <em>ChemElectroChem<\/em>. DOI: <a href=\"https:\/\/doi.org\/10.1002\/celc.201800163\">https:\/\/doi.org\/10.1002\/celc.201800163<\/a><\/p>\n<p>Pollock, Corey, Imboden, Matthias, Stange, Alexander, Javor, Josh, Mahapatra, Koshik, Chiles, Leila, &amp; Bishop, David J. (2018). Engineered PWM Drives for Achieving Rapid Step and Settle Times for MEMS Actuation.\u00a0<em>Journal of Microelectromechanical Systems<\/em>,\u00a0<em>27<\/em>(3). DOI: <a href=\"https:\/\/doi.org\/10.1109\/JMEMS.2018.2826843\">https:\/\/doi.org\/10.1109\/JMEMS.2018.2826843<\/a><\/p>\n<p>Reeves, J.B., Jayne, R.K., Stark, T.J., Barrett, L.K., White, A.E., &amp; Bishop, D.J. (2018). Tunable Infrared Metasurface on a Soft Polymer Scaffold. <em>Nano Letters 18<\/em> (5), 2802-2806. DOI: <a href=\"https:\/\/doi.org\/10.1021\/acs.nanolett.7b05042\">https:\/\/doi.org\/10.1021\/acs.nanolett.7b05042<\/a><\/p>\n<p>Ronaldson-Bouchard, K. &amp; Vunjak-Novakovic, G. (2018). Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development. <em>Cell Stem Cell. <\/em>22(3), 310-324. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.stem.2018.02.011\">https:\/\/doi.org\/10.1016\/j.stem.2018.02.011<\/a><\/p>\n<p>Ronaldson-Bouchard, K., Ma, S.P., Yeager, K., Chen, T., Song, L., Sirabella, D., Morikawa, K., Teles, D., Yazawa, M., &amp; Vunjak-Novakovic, G. (2018). Advanced maturation of human cardiac tissue grown from pluripotent stem cells. <em>Nature<\/em>. 556 (7700), 239-243. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41586-018-0016-3\">https:\/\/doi.org\/10.1038\/s41586-018-0016-3<\/a><\/p>\n<p>Sarwar, M., Rodriguez, P., Li, C. (2019). Sweat-Based in Vitro Diagnostics (IVD): From Sample Collection to Point-of-Care Testing (POCT).\u00a0 <em>Journal of Analysis and Testing<\/em> 3(1): 80-88. DOI: <a href=\"https:\/\/doi.org\/10.1007\/s41664-019-00097-w\">https:\/\/doi.org\/10.1007\/s41664-019-00097-w<\/a><\/p>\n<p>Sentenac, A., &amp; Mertz, J. (2018). Unified description of three-dimensional optical diffraction microscopy: from transmission microscopy to optical coherence tomography: tutorial. <em>J. Opt. Soc. Am. A<\/em>. 35(5), 748-754. DOI: <a href=\"https:\/\/doi.org\/10.1364\/JOSAA.35.000748\">https:\/\/doi.org\/10.1364\/JOSAA.35.000748<\/a><\/p>\n<p>Shain, W.J., Vickers, N.A., Li, J., Han, X., Bifano, T., &amp; Mertz, J. (2018). Axial localization with modulated-illumination extended-depth-of-field microscopy. <em>Biomedical Optics Express<\/em>. 9(4), 1771-1782. DOI: <a href=\"https:\/\/doi.org\/10.1364\/BOE.9.001771\">https:\/\/doi.org\/10.1364\/BOE.9.001771<\/a><\/p>\n<p>Shain, W.J., Vickers, N.A., Negash, A., Bifano, T., Sentenac, A., &amp; Mertz, J. (2017). Dual fluorescence-absorption deconvolution applied to extended-depth-of-field microscopy. <em>Optics Letters<\/em>. 42 (20) 4183-4186. DOI: <a href=\"https:\/\/doi.org\/10.1364\/OL.42.004183\">https:\/\/doi.org\/10.1364\/OL.42.004183<\/a><\/p>\n<p>Sharma A., Toepfer CN.., Ward T., Wasson L., Agarwal R., Conner D.A., Hu J.H., Seidman C.E. (2018). CRISPR\/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells. <em>Curr Protoc Hum Genet<\/em>. 96(1):21.11.1-21.11.20. DOI: <a href=\"https:\/\/doi.org\/10.1002\/cphg.52\">https:\/\/doi.org\/10.1002\/cphg.52<\/a><\/p>\n<p>Stange, A., Imboden, M., Javor, J., Barrett, L. K., &amp; Bishop, D. J. (2019). Building a Casimir metrology platform with a commercial MEMS sensor. <em>Microsystems &amp; Nanoengineering<\/em>, 5(1), 14. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41378-019-0054-5\">https:\/\/doi.org\/10.1038\/s41378-019-0054-5<\/a><\/p>\n<p>Steier, A., Mu\u00f1iz, A., Neale, D., and Lahann, J.* (2019). Emerging Trends in Information-Driven Engineering of Complex Biological Systems. <em>Advanced Materials<\/em>, 1806898. DOI: <a href=\"https:\/\/doi.org\/10.1002\/adma.201806898\">https:\/\/doi.org\/10.1002\/adma.201806898<\/a><\/p>\n<p>Thomas, T., Zhang, C., Nautiyal, P., Boesl, B. Agarwal, A. (2019). 3D Graphene Foam Reinforced Low-Temperature Ceramic with Multifunctional Mechanical, Electrical, and Thermal Properties. <em>Advanced Engineering Materials<\/em>, 1900085. DOI: <a href=\"https:\/\/doi.org\/10.1002\/adem.201900085\">https:\/\/doi.org\/10.1002\/adem.201900085<\/a><\/p>\n<p>Toepfer, C.N., et al. (2019). SarcTrack: An Adaptable Software Tool for Efficient Large-Scale Analysis of Sarcomere Function in hiPSC-Cardiomyocytes. <em>Circulation Research<\/em> 124(8): 1172\u20131183. DOI: <a href=\"https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.314505\">https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.314505<\/a><\/p>\n<p>Tong, L., Mozneb, M., Bravo, E., Ferrando, V., Li, C. (2019). Whole Cell Analysis Ranging from Intercellular Assay to Organ on a Chip. <em>TrAC Trends in Analytical Chemistry<\/em>, In Press. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.trac.2019.05.021\">https:\/\/doi.org\/10.1016\/j.trac.2019.05.021<\/a><\/p>\n<p>Weber, T.D., &amp; Mertz, J. (2018). Retina and Choroid Imaging with Transcranial Back-illumination. In proceedings of <em>Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy\/Translational\/Brain\/OTS), OSA Technical Digest (Optical Society of America, 2018)<\/em>. paper CF3B.8. DOI: <a href=\"https:\/\/doi.org\/10.1364\/TRANSLATIONAL.2018.CF3B.8\">https:\/\/doi.org\/10.1364\/TRANSLATIONAL.2018.CF3B.8<\/a><\/p>\n<p>Xiao, S., Tseng, H., Gritton, H., Han, X., &amp; Mertz, J. (2018). Video-rate volumetric neuronal imaging using 3D targeted illumination. <em>Scientific Reports<\/em> 8 (1): 7921. DOI: <a href=\"https:\/\/doi.org\/10.1038\/s41598-018-26240-8\">https:\/\/doi.org\/10.1038\/s41598-018-26240-8<\/a><\/p>\n<p>Xiao, S., Tseng, H., Gritton, H., Han, X., and Mertz, J. (2018). \u00a0Video-rate volumetric neuronal imaging using 3D targeted illumination.\u00a0 In proceedings of Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy\/Translational\/Brain\/OTS), OSA Technical Digest (Optical Society of America, 2018), paper BW2C.6. DOI: <a href=\"https:\/\/doi.org\/10.1364\/BRAIN.2018.BW2C.6\">https:\/\/doi.org\/10.1364\/BRAIN.2018.BW2C.6<\/a><\/div>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"<p>CELL-MET faculty, trainees, and staff have published over 100 articles. Where available, publicly accessible links are provided below. 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