Fostering Scientific Collaboration and Capacity Strengthening
Responding to emerging infectious diseases (EID) requires not only timely mobilization of public health resources but also scientific capacity and collaboration. Conduct of scientific research during infectious diseases emergencies is often fraught with immense challenges of exchanging information and samples, developing sensible regulatory oversight, setting up equitable and ethical research infrastructure, and sharing results in a timely manner.
Additionally, research capacity has to be universal across low and high resources areas. Research infrastructure in low- and middle-income countries (LMICs) can generate resilience required to combat EID threats, and can help the global community answer relevant scientific questions about these pathogens more effectively, while refining the questions that should be asked. Strong research capacity can lead to more equitable governance of research during outbreaks.
Like prior EID outbreaks, the COVID-19 pandemic has also underscored the need for global collaboration for the development of vaccines, diagnostics and therapeutics. The pandemic also reveals the need for broader conversation, increased understanding and transparency, international collaboration, and multi-stakeholder involvement in scientific diplomacy worldwide. Critical to this effort is an understanding of the role that maximum- and high-containment research laboratories play in pandemic preparedness and in providing infrastructure for rapidly deployed measures of collecting data and specimens from animals and humans to support researchers in their quest for understanding emerging pathogens — during outbreaks and in preparation for the next inevitable threat. CEID’s work in this space aims to strengthen collaboration among key players in forging the path towards a faster and more equitable global scientific response by identifying key programmatic and policy interventions in this space.
Our Current Work In This Space:
Lessons from COVID-19 Pandemic for High and Maximum Research and Sample Sharing in Emergency Settings
Overview
This research examines the scientific, regulatory and logistic challenges as well as ethical dilemmas surrounding sharing pathogen sample sharing during EID outbreaks.
- What did COVID-19 pandemic teach us about sample sharing for timely research in emergencies?
- What research is specific to high and maximum containment laboratories?
- How can multiple stakeholders work together to improve the processes?
- How do we ensure equity in research representation and benefits of research?
Project Faculty & Collaborators
- Gerald Keusch, MD, Professor, Medicine & International Health, Boston University School of Medicine
- Ron Corley, PhD, Chair, Department of Microbiology, Boston University School of Medicine, Director, National Emerging Infectious Diseases Laboratories
- Adam Hume, PhD, Research Assistant Professor, National Emerging Infectious Diseases Laboratories
- Lauren Sauer, PhD, Associate Professor, UNMC College of Public Health; Director of the Special Pathogens Research Network with the National Emerging Special Pathogens Training and Education Center (NETEC), CEID Adjunct Faculty
- Nahid Bhadelia, MD, MALD, Director, CEID
- Scott Seitz, PhD, Postdoctoral Fellow of Microbiology, Connor Lab, National Emerging Infectious Diseases Laboratories
Other Related Resources
Related CEID Faculty Publications
- Integrating Clinical Research into Epidemic Response: The Ebola Experience, Gerald Keusch, MD, editor
- Clinical trials during epidemics, Gerald Keusch, MD, co-author
- In search of global governance for research in epidemics., Gerald Keusch, MD, co-author
- The R&D Preparedness Ecosystem: Preparedness for Health Emergencies
Report to the Global Preparedness Monitoring Board, Gerald Keusch, MD, co-author
- Designing an R&D Preparedness and Response Ecosystem for Potentially Pandemic Pathogens, Gerald Keusch, MD, co-author
- Urgent lessons from COVID 19: why the world needs a standing, coordinated system and sustainable financing for global research and development, Gerald Keusch, MD, co-author
- Science, not speculation, is essential to determine how SARS-CoV-2 reached humans, Gerald Keusch, MD, co-author
- Maximum Containment Infectious Disease Laboratories as an Integral Part of Emergency Preparedness and Emergency Response by Sarah Carpenter, MD & Nahid Bhadelia, MD, MALD