{"id":5982,"date":"2023-06-18T13:54:39","date_gmt":"2023-06-18T17:54:39","guid":{"rendered":"https:\/\/www.bu.edu\/cbr\/?post_type=profile&#038;p=5982"},"modified":"2026-03-25T14:03:02","modified_gmt":"2026-03-25T18:03:02","slug":"isaac-falconer","status":"publish","type":"profile","link":"https:\/\/www.bu.edu\/cbr\/profile\/isaac-falconer\/","title":{"rendered":"Issac Falconer"},"content":{"rendered":"<p>Research Interests:<span> Functional reorganization of brain networks in post-stroke aphasia. Resting state functional connectivity and predicting language recovery. Dynamic functional network connectivity and neuroplasticity in post-stroke aphasia.<\/span><\/p>\n<p>Current Project:<a href=\"https:\/\/www.bu.edu\/aphasiaresearch\/research\/neural-markers\/multiple-demand-md-study\/\"> MD Project<\/a><\/p>\n<p>LinkedIn <a href=\"http:\/\/linkedin.com\/in\/isaac-falconer-72aab890\">Profile<\/a><\/p>\n<p>Google Scholar <a href=\"https:\/\/scholar.google.com\/citations?hl=en&amp;user=0pttK7AAAAAJ\">Profile<\/a><\/p>\n<p>Social Media Handle: @issacfalconer<\/p>\n<p>Peer Reviewed Publications:<\/p>\n<p><span>Marte, M. J., Carpenter, E., Falconer, I. B., Scimeca, M., Abdollahi, F., Pe\u00f1aloza, C., &amp; Kiran, S. (2022). LEX-BADAT: Language EXperience in Bilinguals With and Without Aphasia DATaset. Frontiers in Psychology, 13(June), 1\u20136. https:\/\/doi.org\/10.3389\/fpsyg.2022.875928 <\/span><\/p>\n<p><span>Abo, K. M., de Aja, J. S., Lindstrom-Vautrin, J., Alysandratos, K. D., Richards, A., Garcia-De-Alba, C., Huang, J., Hix, O. T., Werder, R. B., Bullitt, E., Hinds, A., Falconer, I., Villacorta-Martin, C., Jaenisch, R., Kim, C. F., Kotton, D. N., &amp; Wilson, A. A. (2022). Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell-derived alveolar epithelium. JCI Insight, 7(6). https:\/\/doi.org\/10.1172\/jci.insight.155589 <\/span><\/p>\n<p><span>Nichols, P. J., Falconer, I., Griffin, A., Mant, C., Hodges, R., McKnight, C. J., V\u00f6geli, B., &amp; Vugmeyster, L. (2020). Deuteration of nonexchangeable protons on proteins affects their thermal stability, side-chain dynamics, and hydrophobicity. Protein Science, 29(7). https:\/\/doi.org\/10.1002\/pro.3878 <\/span><\/p>\n<p><span>Falconer, I. B., Mant, C. T., McKnight, C. J., Vugmeyster, L., &amp; Hodges, R. (2017). Optimized purification of a fusion protein by reversed-phase high performance liquid chromatography informed by the linear solvent strength model. Journal of Chromatography A, 1521. https:\/\/doi.org\/10.1016\/j.chroma.2017.08.080 <\/span><\/p>\n<p><span>Vugmeyster, Liliya, Ostrovsky, D., Hoatson, G. L., Qiang, W., &amp; Falconer, I. B. (2017). Solvent-Driven Dynamical Crossover in the Phenylalanine Side-Chain from the Hydrophobic Core of Amyloid Fibrils Detected by 2H NMR Relaxation. Journal of Physical Chemistry B, 121(30). https:\/\/doi.org\/10.1021\/acs.jpcb.7b04726 <\/span><\/p>\n<p><span>Vugmeyster, L., Ostrovsky, D., Clark, M. A., Falconer, I. B., Hoatson, G. L., &amp; Qiang, W. (2016). Fast Motions of Key Methyl Groups in Amyloid-\u03b2 Fibrils. Biophysical Journal, 111(10). https:\/\/doi.org\/10.1016\/j.bpj.2016.10.001 Vugmeyster, Liliya, Clark, M. A., Falconer, I. B., Ostrovsky, D., Gantz, D., Qiang, W., &amp; Hoatson, G. L. (2016). Flexibility and solvation of amyloid-\u03b2 hydrophobic core. Journal of Biological Chemistry, 291(35), 18484\u201318495. https:\/\/doi.org\/10.1074\/jbc.M116.740530<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>Conference Presentations:<\/p>\n<p><span>Falconer, I. B., Varkanitsa, M., &amp; Kiran, S. People with post-stroke aphasia have reduced temporal variability of functional connectivity in the language network compared to healthy controls. 60th Annual Academy of Aphasia Meeting. 2022. Philadelphia, PA <\/span><\/p>\n<p><span>Falconer, I., Varkanitsa, M., &amp; Kiran, S. Dynamic resting state functional connectivity predicts treatment response in people with post-stroke aphasia. Organization for Human Brain Mapping. 2022. Glasgow, UK <\/span><\/p>\n<p><span>Falconer, I., Varkanitsa, M., &amp; Kiran, S. (2021). Pre-treatment graph measures of resting-state functional connectivity predict language treatment outcome in aphasia. Society for the Neurobiology of Language. 2021 (virtual). https:\/\/www.neurolang.org\/programs\/SNL_2021_Program.pdf<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>Awards and Recognition:<\/p>\n<p><span>2023 NIDCD Research Symposium in Clinical Aphasiology Fellowship<\/span><\/p>\n","protected":false},"author":22217,"template":"","_links":{"self":[{"href":"https:\/\/www.bu.edu\/cbr\/wp-json\/wp\/v2\/profile\/5982"}],"collection":[{"href":"https:\/\/www.bu.edu\/cbr\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bu.edu\/cbr\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/cbr\/wp-json\/wp\/v2\/users\/22217"}],"version-history":[{"count":3,"href":"https:\/\/www.bu.edu\/cbr\/wp-json\/wp\/v2\/profile\/5982\/revisions"}],"predecessor-version":[{"id":5985,"href":"https:\/\/www.bu.edu\/cbr\/wp-json\/wp\/v2\/profile\/5982\/revisions\/5985"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/cbr\/wp-json\/wp\/v2\/media?parent=5982"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}