Study for Alcohol Reduction (STAR)

What is the purpose of this study?
The Study for Alcohol Reduction (StAR) is a federally funded research program at Boston University. The purpose of this study is to further investigate a medication called Zonisamide (ZON), which has been shown to be more effective than a placebo in reducing alcohol consumption.

Who qualifies to participate in this study?
We are currently enrolling individuals who are 21-65 years old and are moderate to heavy alcohol drinkers wishing to cut back or stop alcohol use. Individuals will be required to undergo a screening assessment to determine eligibility in the study.

What will participants be doing in this study?
If you participate in the study, you will receive either:
1. Zonisamide medication and a computerized alcohol reduction program called Take Control, or
2. Placebo treatment with Take Control

All participants enrolled in the study will be asked to attend 14 weekly sessions, provide urine and blood tests, and track and report possible side effects. In addition, some participants will be asked to undergo two noninvasive brain scans, called fMRIs.

Eligible participants will be compensated for completion of study procedures.

Interested in this study?

  • Call (857-895-2248) or email ( the StAR program if you are interested in learning more.
  • Visit our web page for more information about the study and research staff.