Our study on optical scattering for chemo monitoring is published in Neoplasia

In this work we used SFDI to monitor optical scattering in prostate and breast animal tumor models. We found that the reduced scattering coefficient was strongly correlated with apoptosis, and the scattering power was strongly correlated with proliferation. This helped us track treatment response to cyclophosphamide and the antiangiogenic DC101. This work helps establish optical scattering as an important label-free optical marker of anti-cancer treatment response that can be used with other more common markers, such as oxygen saturation, hemoglobin levels, water, and lipids. It also helps make the case for frequency-domain and/or time-domain diffuse optical techniques such as SFDI, DOS, FD-NIRS, etc. which can quantify optical scattering in thick tissue.

paper here

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