Publications

2026
  • Coming Soon
2025

  • Alnahhas RN, Andreani V, Dunlop MJ. Evaluating the predictive power of combined gene expression dynamics from single cells on antibiotic survival. mSystems. 2025 Jun 17;10(6):e0158824. doi: 10.1128/msystems.01588-24. Read here
  • Baka T, Moore J, Qin F, Yurista SR, Zhang A, He H, Chambers JM, Croteau D, Goel RK, Smith H, Wang MC, Chen CS, Hobai IA, Rombaldova M, Kuda O, Tardiff JC, Balschi JA, Pimentel DR, Seidman CE, Seidman JG, Emili A, Colucci WS, Luptak I. Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model. Eur Heart J. 2025 Oct 22;46(40):4105-4119. doi: 10.1093/eurheartj/ehaf324. Read here
  • Chen J, Borison A, Densmore D, Wong WW. Cell-free recombinase-integrated Boolean output system. Cell Syst. 2025 Oct 15;16(10):101395. doi: 10.1016/j.cels.2025.101395. Read here
  • Ching T, van Steen ACI, Gray-Scherr D, Teo JL, Vasan A, Jeon J, Shah J, Patel A, Stoddard AE, Bays JL, Eyckmans J, Chen CS. TapeTech microfluidic connectors: adhesive tape-enabled solution for organ-on-a-chip system integration. Lab Chip. 2025 Mar 11;25(6):1474-1488. doi: 10.1039/d4lc00970c. Read here
  • Descoteaux AE, Radulovic M, Alburi D, Bradham CA. CMTM4 is an adhesion modulator that regulates skeletal patterning and primary mesenchyme cell migration in sea urchin embryos. Dev Biol. 2025 May;521:85-95. doi: 10.1016/j.ydbio.2025.02.009. Read here
  • Dukovski I, Golden L, Zhang J, Osborne M, Segrè D, Korolev KS. Biophysical metabolic modeling of complex bacterial colony morphology. Cell Syst. 2025 Aug 20;16(8):101352. doi: 10.1016/j.cels.2025.101352. Read here
  • Ewoldt JK, DePalma SJ, Jewett ME, Karakan MÇ, Lin YM, Mir Hashemian P, Gao X, Lou L, McLellan MA, Tabares J, Ma M, Salazar Coariti AC, He J, Toussaint KC Jr, Bifano TG, Ramaswamy S, White AE, Agarwal A, Lejeune E, Baker BM, Chen CS. Induced pluripotent stem cell-derived cardiomyocyte in vitro models: benchmarking progress and ongoing challenges. Nat Methods. 2025 Jan;22(1):24-40. doi: 10.1038/s41592-024-02480-7. Read here
  • Feng Z, Blumenthal E, Mehta P, Goyal A. A theory of ecological invasions and its implications for eco-evolutionary dynamics. Proc Natl Acad Sci U S A. 2025 Dec 9;122(49):e2505850122. doi: 10.1073/pnas.2505850122. Read here
  • Floros KV, Fairchild CK Jr, Li J, Zhang K, Roberts JL, Kurupi R, Paudel D, Xing Y, Hu B, Kraskauskiene V, Hosseini N, Shen S, Inge MM, Smith-Fry K, Li L, Sotiriou A, Dalton KM, Jose A, Abdelfadiel EI, Hill RD, Slaughter JM, Shende M, Lorenz MR, Tanaka N, Kajino T, Nelson ML, Hinojosa MR, Kehinde VA, Belvin BR, Sugiokto FG, Lai Z, Dimopoulos AC, Boikos SA, Stamatouli AM, Lewis JP, Manjili MH, Ebi H, Valerie K, Li R, Poklepovic A, Koblinski JE, Siggers T, Banito A, Dozmorov MG, Jones KB, Radhakrishnan SK, Faber AC. Targeting SUMOylation promotes cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma. Nat Commun. 2025 Nov 5;16(1):9761. doi: 10.1038/s41467-025-64665-8. Read here
  • Gibbs JR, Mei C, Wunderlich Z. Beyond the heat shock pathway: Heat stress responses in Drosophila development. Dev Biol. 2025 Feb;518:53-60. doi: 10.1016/j.ydbio.2024.11.003. Read here
  • Goyal A, Rocks JW, Mehta P. Universal Niche Geometry Governs the Response of Ecosystems to Environmental Perturbations. PRX Life. 2025 Feb-Apr;3(1):10.1103/prxlife.3.013010. doi: 10.1103/prxlife.3.013010. Read here
  • Incandela JT, Hu K, Joshi P, Rosenstein JK, Larkin JW. Non-optical, label-free electrical capacitance imaging of microorganisms. mBio. 2025 Sep 10;16(9):e0167625. doi: 10.1128/mbio.01676-25. Read here
  • Kang NR, Im J, Biondo JR, Sharpes CE, Rhea KA, Garden PM, Jaramillo Montezco JJ, Ringaci A, Grinstaff MW, Phillips DA, Miklos AE, Green AA. A Rapid and Modular Nanobody Assay for Plug-and-Play Antigen Detection. ACS Synth Biol. 2025 Sep 19;14(9):3423-3433. doi: 10.1021/acssynbio.5c00182. Read here
  • Kuffner CJ, Marzilli AM, Ngo JT. RNA-stabilized coat proteins for sensitive and simultaneous imaging of distinct single mRNAs in live cells. Nat Methods. 2025 Sep 22:10.1038/s41592-025-02782-4. doi: 10.1038/s41592-025-02782-4. Read here
  • Lambourne L, Mattioli K, Santoso C, Sheynkman G, Inukai S, Kaundal B, Berenson A, Spirohn-Fitzgerald K, Bhattacharjee A, Rothman E, Shrestha S, Laval F, Carroll BS, Plassmeyer SP, Emenecker RJ, Yang Z, Bisht D, Sewell JA, Li G, Prasad A, Phanor S, Lane R, Moyer DC, Hunt T, Balcha D, Gebbia M, Twizere JC, Hao T, Holehouse AS, Frankish A, Riback JA, Salomonis N, Calderwood MA, Hill DE, Sahni N, Vidal M, Bulyk ML, Fuxman Bass JI. Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms. Mol Cell. 2025 Apr 3;85(7):1445-1466.e13. doi: 10.1016/j.molcel.2025.03.004. Read here
  • Le Q, Ngo JT. Protease-Containing Nanobodies for Detecting and Manipulating Intracellular Antigens Using Antiviral Drugs. ACS Chem Biol. 2025 Jun 20;20(6):1145-1152. doi: 10.1021/acschembio.5c00176. Read here
  • Li L, Yang J, Perry L, Bays JL, Bhatia SN, Eyckmans J, Chen CS. Engineering a heparin-mimetic biomaterial to promote tissue vascularization. Commun Biol. 2025 Nov 14;8(1):1570. doi: 10.1038/s42003-025-08946-4. Read here
  • Li Z, Fuxman Bass JI. ICARus: a pipeline to extract robust gene expression signatures from transcriptome datasets. Front Bioinform. 2025 Jun 19;5:1604418. doi: 10.3389/fbinf.2025.1604418. Read here
  • Lin H, Seitz S, Tan Y, Lugagne JB, Wang L, Ding G, He H, Rauwolf TJ, Dunlop MJ, Connor JH, Porco JA Jr, Tian L, Cheng JX. Label-free nanoscopy of cell metabolism by ultrasensitive reweighted visible stimulated Raman scattering. Nat Methods. 2025 May;22(5):1040-1050. doi: 10.1038/s41592-024-02575-1. Read here
  • Lion AT, Bodine SM, McCutcheon KR, Ghogale M, Chandragiri S, Abayawardena D, Shrestha BD, Descoteaux A, Alvarez K, Balkman JA, Cocke B, Wikramanayake AH, Schlezinger J, Wong JY, Prakash VN, Bradham CA. PFAS compounds PFOA and Gen X are teratogenic to sea urchin embryos. Dev Biol. 2025 Sep;525:139-154. doi: 10.1016/j.ydbio.2025.06.004. Read here
  • Lu C, Li Y, Cummings JR, Banskota S. Delivery of genome editors with engineered virus-like particles. Methods Enzymol. 2025;712:475-516. doi: 10.1016/bs.mie.2025.01.007. Read here
  • McGee JE, Kirsch JR, Kenney D, Cerbo F, Chavez EC, Shih TY, Douam F, Wong WW, Grinstaff MW. Complete substitution with modified nucleotides in self-amplifying RNA suppresses the interferon response and increases potency. Nat Biotechnol. 2025 May;43(5):720-726. doi: 10.1038/s41587-024-02306-z. Read here
  • McIntyre D, Arguijo D, Kawata K, Densmore D. Component library creation and pixel array generation with micromilled droplet microfluidics. Microsyst Nanoeng. 2025 Jan 14;11(1):6. doi: 10.1038/s41378-024-00839-6. Read here
  • Moyer DC, Reimertz J, Fuxman Bass JI, Segrè D. Flux sampling and context-specific genome-scale metabolic models for biotechnological applications. Trends Biotechnol. 2025 Aug 7:S0167-7799(25)00271-9. doi: 10.1016/j.tibtech.2025.07.010. Read here
  • Moyer DC, Reimertz J, Segrè D, Fuxman Bass JI. MACAW: a method for semi-automatic detection of errors in genome-scale metabolic models. Genome Biol. 2025 Mar 28;26(1):79. doi: 10.1186/s13059-025-03533-6. Read here
  • Mulder OJ, Peters Kostman M, Almodaimegh A, Edge MD, Larkin JW. An agent-based model of metabolic signaling oscillations in Bacillus subtilis biofilms. PLoS Comput Biol. 2025 Dec 4;21(12):e1013746. doi: 10.1371/journal.pcbi.1013746. Read here
  • O’Connor OM, Dunlop MJ. Cell-TRACTR: A transformer-based model for end-to-end segmentation and tracking of cells. PLoS Comput Biol. 2025 May 23;21(5):e1013071. doi: 10.1371/journal.pcbi.1013071. Read here
  • Padmakumar JP, Sun JJ, Cho W, Zhou Y, Krenz C, Han WZ, Densmore D, Sontag ED, Voigt CA. Partitioning of a 2-bit hash function across 66 communicating cells. Nat Chem Biol. 2025 Feb;21(2):268-279. Read here
  • Patalano SD, Fuxman Bass P, Fuxman Bass JI. Transcription factors in the development and treatment of immune disorders. Transcription. 2025 Feb;16(1):118-140. doi: 10.1080/21541264.2023.2294623. Epub 2023 Dec 15. Read here
  • Peng H, Kotelnikov S, Egbert ME, Ofaim S, Stevens GC, Phanse S, Saccon T, Ignatov M, Dutta S, Istace Z, Moutaoufik MT, Aoki H, Kewalramani N, Sun J, Gong Y, Padhorny D, Poda G, Alekseenko A, Porter KA, Jones G, Rodionova I, Guo H, Pogoutse O, Datta S, Saier M, Crovella M, Vajda S, Moreno-Hagelsieb G, Parkinson J, Segre D, Babu M, Kozakov D, Emili A. Ligand interaction landscape of transcription factors and essential enzymes in E. coli. Cell. 2025 Mar 6;188(5):1441-1455.e15. Read here
  • Rijal K, Mehta P. A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits. Elife. 2025 Mar 17;14:RP103877. doi: 10.7554/eLife.103877. Read here
  • Riley AT, Robson JM, Ulanova A, Green AA. Generative and predictive neural networks for the design of functional RNA molecules. Nat Commun. 2025 May 4;16(1):4155. doi: 10.1038/s41467-025-59389-8. Read here
  • Scott H, Segrè D. Metabolic Flux Modeling in Marine Ecosystems. Ann Rev Mar Sci. 2025 Jan;17(1):593-620. doi: 10.1146/annurev-marine-032123-033718. Read here
  • Tous C, Kinstlinger IS, Rice MEL, Deng J, Wong WW. Multiplexing light-inducible recombinases to control cell fate, Boolean logic, and cell patterning in mammalian cells. Sci Adv. 2025 May 9;11(19):eadt1971. doi: 10.1126/sciadv.adt1971. Read here
  • Tran JC, Kuffner CJ, Marzilli AM, Miller RE, Silfen ZE, McMahan JB, Sloas DC, Chen CS, Ngo JT. Fluorescein-based SynNotch adaptors for regulating gene expression responses to diverse extracellular and matrix-based cues. Nat Commun. 2025 Jan 20;16(1):852. doi: 10.1038/s41467-025-56148-7. Read here
  • Vasan A, Kim S, Davis E, Roh DS, Eyckmans J. Advances in Designer Materials for Chronic Wound Healing. Adv Wound Care. 2025 Oct;14(10):552-568. doi: 10.1089/wound.2024.0108. Read here
  • Yan Z, Li Y, Eshed A, Wu K, Ticktin ZM, Murugan V, Lim ES, Hong F, Green AA. Programmable fluorescent aptamer-based RNA switches for rapid identification of point mutations. Nat Chem. 2025 Dec;17(12):1826-1838. doi: 10.1038/s41557-025-01995-6. Read here
  • Yang X, Rocks JW, Jiang K, Walters AJ, Rai K, Liu J, Nguyen J, Olson SD, Mehta P, Collins JJ, Daringer NM, Bashor CJ. Engineering synthetic phosphorylation signaling networks in human cells. Science. 2025 Jan 3;387(6729):74-81. doi: 10.1126/science.adm8485. Read here
  • Yazicigil RT, Bali A, Caygara D, Densmore D. Improving engineered biological systems with electronics and microfluidics. Nat Biotechnol. 2025 Jul;43(7):1067-1083. doi: 10.1038/s41587-025-02709-6. Read here
  • Zhou Y, Voigt CA, Densmore D. Constraint-Based Sub-Graph Partitioning for Multi-Cellular Biological Networks. IEEE Trans Comput Biol Bioinform. 2025 Jul-Aug;22(4):1888-1901. doi: 10.1109/TCBBIO.2025.3575288. Read here

 

2024

  • Abdelatty M, Incandela J, Hu K, Joshi P, Larkin JW, Reda S, Rosenstein JK. Electrical Capacitance Tomography of Cell Cultures on a CMOS Microelectrode Array. IEEE Trans Biomed Circuits Syst. 2024 Aug;18(4):799-809. doi: 10.1109/TBCAS.2024.3415360. Read here

  • Adams SC, Nambiar AK, Bressler EM, Raut CP, Colson YL, Wong WW, Grinstaff MW. Immunotherapies for locally aggressive cancers. Adv Drug Deliv Rev. 2024 Jul;210:115331. doi: 10.1016/j.addr.2024.115331. Read here

  • Andreani V, South EJ, Dunlop MJ. Generating information-dense promoter sequences with optimal string packing. PLoS Comput Biol. 2024 Jul 24;20(7):e1012276. doi: 10.1371/journal.pcbi.1012276. Read here

  • Blumenthal E, Rocks JW, Mehta P. Phase Transition to Chaos in Complex Ecosystems with Nonreciprocal Species-Resource Interactions. Phys Rev Lett. 2024 Mar 22;132(12):127401. doi: 10.1103/PhysRevLett.132.127401. Read more

  • Burgess CL, Huang J, Bawa PS, Alysandratos KD, Minakin K, Ayers LJ, Morley MP, Babu A, Villacorta-Martin C, Yampolskaya M, Hinds A, Thapa BR, Wang F, Matschulat A, Mehta P, Morrisey EE, Varelas X, Kotton DN. Generation of human alveolar epithelial type I cells from pluripotent stem cells. Cell Stem Cell. 2024 May 2;31(5):657-675.e8. doi: 10.1016/j.stem.2024.03.017. Read here

  • Ding Y, Tous C, Choi J, Chen J, Wong WW. Orthogonal inducible control of Cas13 circuits enables programmable RNA regulation in mammalian cells. Nat Commun. 2024 Feb 21;15(1):1572. doi: 10.1038/s41467-024-45795-x. Read here

  • Ewoldt JK, Wang MC, McLellan MA, Cloonan PE, Chopra A, Gorham J, Li L, DeLaughter DM, Gao X, Lee JH, Willcox JAL, Layton O, Luu RJ, Toepfer CN, Eyckmans J, Seidman CE, Seidman JG, Chen CS. Hypertrophic cardiomyopathy-associated mutations drive stromal activation via EGFR-mediated paracrine signaling. Sci Adv. 2024 Oct 18;10(42):eadi6927. doi: 10.1126/sciadv.adi6927. Read here

  • Feaster TK, Ewoldt JK, Avila A, Casciola M, Narkar A, Chen CS, Blinova K. Nonclinical evaluation of chronic cardiac contractility modulation on 3D human engineered cardiac tissues. J Cardiovasc Electrophysiol. 2024 May;35(5):895-905. doi: 10.1111/jce.16222. Read here

  • Feng Z, Marsland R 3rd, Rocks JW, Mehta P. Emergent competition shapes top-down versus bottom-up control in multi-trophic ecosystems. PLoS Comput Biol. 2024 Feb 8;20(2):e1011675. doi: 10.1371/journal.pcbi.1011675. Read here

  • Frankel NW, Deng H, Yucel G, Gainer M, Leemans N, Lam A, Li Y, Hung M, Lee D, Lee CT, Banicki A, Tian M, Almudhfar N, Naitmazi L, Roguev A, Lee S, Wong W, Gordley R, Lu TK, Garrison BS. Precision off-the-shelf natural killer cell therapies for oncology with logic-gated gene circuits. Cell Rep. 2024 May 28;43(5):114145. doi: 10.1016/j.celrep.2024.114145. Read here

  • Gagnon KA, Huang J, Hix OT, Hui VW, Hinds A, Bullitt E, Eyckmans J, Kotton DN, Chen CS. Multicompartment duct platform to study epithelial-endothelial crosstalk associated with lung adenocarcinoma. APL Bioeng. 2024 Jun 17;8(2):026126. doi: 10.1063/5.0207228. Read here

  • He XA, Berenson A, Bernard M, Weber C, Cook LE, Visel A, Fuxman Bass JI, Fisher S. Identification of conserved skeletal enhancers associated with craniosynostosis risk genes. Hum Mol Genet. 2024 May 4;33(10):837-849. doi: 10.1093/hmg/ddad182. Read here

  • Herbst K, Wang T, Forchielli EJ, Thommes M, Paschalidis IC, Segrè D. Multi-Attribute Subset Selection enables prediction of representative phenotypes across microbial populations. Commun Biol. 2024 Apr 3;7(1):407. doi: 10.1038/s42003-024-06093-w. Read here

  • Inge MM, Miller R, Hook H, Bray D, Keenan JL, Zhao R, Gilmore TD, Siggers T. Rapid profiling of transcription factor-cofactor interaction networks reveals principles of epigenetic regulation. Nucleic Acids Res. 2024 Sep 23;52(17):10276-10296. doi: 10.1093/nar/gkae706. Read here

  • Jafarbeglou F, Dunlop MJ. Red Light Responsive Cre Recombinase for Bacterial Optogenetics. ACS Synth Biol. 2024 Dec 20;13(12):3991-4001. doi: 10.1021/acssynbio.4c00388. Read here

  • Karakan MÇ, Ewoldt JK, Segarra AJ, Sundaram S, Wang MC, White AE, Chen CS, Ekinci KL. Geometry and length control of 3D engineered heart tissues using direct laser writing. Lab Chip. 2024 Mar 12;24(6):1685-1701. doi: 10.1039/d3lc00752a. Read here

  • Kim Y, Kim SW, Saul D, Neyazi M, Schmid M, Wakimoto H, Slaven N, Lee JH, Layton O, Wasson LK, Letendre JH, Xiao F, Ewoldt JK, Gkatzis K, Sommer P, Gobert B, Wiest-Daesslé N, McAfee Q, Singhal N, Lun M, Gorham JM, Arany Z, Sharma A, Toepfer CN, Oudit GY, Pu WT, Dickel DE, Pennacchio LA, Visel A, Chen CS, Seidman JG, Seidman CE. Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer. J Clin Invest. 2024 Dec 17;135(4):e183353. doi: 10.1172/JCI183353. Read here

  • Kobeissi H, Jilberto J, Karakan MÇ, Gao X, DePalma SJ, Das SL, Quach L, Urquia J, Baker BM, Chen CS, Nordsletten D, Lejeune E. MicroBundleCompute: Automated segmentation, tracking, and analysis of subdomain deformation in cardiac microbundles. PLoS One. 2024 Mar 26;19(3):e0298863. doi: 10.1371/journal.pone.0298863. Read here

  • Lammers A, Hsu HH, Sundaram S, Gagnon KA, Kim S, Lee JH, Tung YC, Eyckmans J, Chen CS. Rapid Tissue Perfusion Using Sacrificial Percolation of Anisotropic Networks. Matter. 2024 Jun 5;7(6):2184-2204. doi: 10.1016/j.matt.2024.04.001. Read here

  • Lashkaripour A, McIntyre DP, Calhoun SGK, Krauth K, Densmore DM, Fordyce PM. Design automation of microfluidic single and double emulsion droplets with machine learning. Nat Commun. 2024 Jan 2;15(1):83. doi: 10.1038/s41467-023-44068-3. Read here

  • Lawton ML, Inge MM, Blum BC, Smith-Mahoney EL, Bolzan D, Lin W, McConney C, Porter J, Moore J, Youssef A, Tharani Y, Varelas X, Denis GV, Wong WW, Padhorny D, Kozakov D, Siggers T, Wuchty S, Snyder-Cappione J, Emili A. Multiomic profiling of chronically activated CD4+ T cells identifies drivers of exhaustion and metabolic reprogramming. PLoS Biol. 2024 Dec 17;22(12):e3002943. doi: 10.1371/journal.pbio.3002943. Read here

  • Li L, Griebel ME, Uroz M, Bubli SY, Gagnon KA, Trappmann B, Baker BM, Eyckmans J, Chen CS. A Protein-Adsorbent Hydrogel with Tunable Stiffness for Tissue Culture Demonstrates Matrix-Dependent Stiffness Responses. Adv Funct Mater. 2024 Apr 25;34(17):2309567. doi: 10.1002/adfm.202309567. Read here

  • Liu Q, Mendoza DA, Yasar A, Caygara D, Kassem A, Densmore D, Yazicigil RT. Integrated Real-Time CMOS Luminescence Sensing and Impedance Spectroscopy in Droplet Microfluidics. IEEE Trans Biomed Circuits Syst. 2024 Dec;18(6):1233-1252. doi: 10.1109/TBCAS.2024.3491594. Read here

  • Lu Y, Berenson A, Lane R, Guelin I, Li Z, Chen Y, Shah S, Yin M, Soto-Ugaldi LF, Fiszbein A, Fuxman Bass JI. A large-scale cancer-specific protein-DNA interaction network. Life Sci Alliance. 2024 Jul 16;7(10):e202402641. doi: 10.26508/lsa.202402641. Read here

  • Lugagne JB, Blassick CM, Dunlop MJ. Deep model predictive control of gene expression in thousands of single cells. Nat Commun. 2024 Mar 8;15(1):2148. doi: 10.1038/s41467-024-46361-1. Read here

  • Natarajan A, Kim S, Moreno GH, Eyckmans J, Chen CS, Dean D, Vijayan VM. 3D printing assisted surface patterning process on acrylated hydrogels for contact guidance of fibroblasts. Colloids Surf B Biointerfaces. 2024 Oct;242:114099. doi: 10.1016/j.colsurfb.2024.114099. Read here

  • Rocks JW, Mehta P. Integrating local energetics into Maxwell-Calladine constraint counting to design mechanical metamaterials. Phys Rev E. 2024 Aug;110(2-2):025002. doi: 10.1103/PhysRevE.110.025002. Read here

  • Roehner N, Roberts J, Lapets A, Gould D, Akavoor V, Qin L, Gordon DB, Voigt C, Densmore D. GOLDBAR: A Framework for Combinatorial Biological Design. ACS Synth Biol. 2024 Sep 20;13(9):2899-2911. doi: 10.1021/acssynbio.4c00296. Read here

  • Rottenberg JT, Taslim TH, Soto-Ugaldi LF, Martinez-Cuesta L, Martinez-Calejman C, Fuxman Bass JI. Viral cis-regulatory elements as sensors of cellular states and environmental cues. Trends Genet. 2024 Sep;40(9):772-783. doi: 10.1016/j.tig.2024.05.004. Read here

  • Silverstein MR, Bhatnagar JM, Segrè D. Metabolic complexity drives divergence in microbial communities. Nat Ecol Evol. 2024 Aug;8(8):1493-1504. doi: 10.1038/s41559-024-02440-6. Read here

  • Sundaram S, Lee JH, Bjørge IM, Michas C, Kim S, Lammers A, Mano JF, Eyckmans J, White AE, Chen CS. Sacrificial capillary pumps to engineer multiscalar biological forms. Nature. 2024 Dec;636(8042):361-367. doi: 10.1038/s41586-024-08175-5. Read here

  • Tague N, Coriano-Ortiz C, Sheets MB, Dunlop MJ. Light-inducible protein degradation in E. coli with the LOVdeg tag. Elife. 2024 Jan 25;12:RP87303. doi: 10.7554/eLife.87303. Read here

  • Uroz M, Stoddard AE, Sutherland BP, Courbot O, Oria R, Li L, Ravasio CR, Ngo MT, Yang J, Tefft JB, Eyckmans J, Han X, Elosegui-Artola A, Weaver VM, Chen CS. Differential stiffness between brain vasculature and parenchyma promotes metastatic infiltration through vessel co-option. Nat Cell Biol. 2024 Dec;26(12):2144-2153. doi: 10.1038/s41556-024-01532-6. Read here

  • Van Dover G, Javor J, Ewoldt JK, Zhernenkov M, Wąsik P, Freychet G, Lee J, Brown D, Chen CS, Bishop DJ. Structural maturation of myofilaments in engineered 3D cardiac microtissues characterized using small angle x-ray scattering. Phys Biol. 2024 Mar 20;21(3). Read here

  • Yan Z, Eshed A, Tang AA, Arevalos NR, Ticktin ZM, Chaudhary S, Ma D, McCutcheon G, Li Y, Wu K, Saha S, Alcantar-Fernandez J, Moreno-Camacho JL, Campos-Romero A, Collins JJ, Yin P, Green AA. Rapid, Multiplexed, and Enzyme-Free Nucleic Acid Detection Using Programmable Aptamer-Based RNA Switches. Chem. 2024 Jul 11;10(7):2220-2244. doi: 10.1016/j.chempr.2024.03.015. Read here

  • Yordanov TE, Keyser MS, Enriquez Martinez MA, Esposito T, Tefft JB, Morris EK, Labzin LI, Stehbens SJ, Rowan AE, Hogan BM, Chen CS, Lauko J, Lagendijk AK. Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels. APL Bioeng. 2024 Feb 12;8(1):016108. doi: 10.1063/5.0159330. Read here

  • Zhou Y, Sheng P, Li J, Li Y, Xie M, Green AA. Conditional RNA interference in mammalian cells via RNA transactivation. Nat Commun. 2024 Aug 10;15(1):6855. doi: 10.1038/s41467-024-50600-w. Read here