Alexander Green

The Green lab applies the principles of self-assembly to develop new techniques for programming and probing biology. We use in silico tools to design RNA molecules from scratch that respond to stimuli and execute biomolecular programs in living cells. We engineer nucleic acids that sense and amplify molecular cues to develop diagnostic assays that are portable, low cost, and easy to use. We self-assemble complexes of nucleic acids, proteins, and other components and apply them to produce new chemicals and act as intracellular probes.