John Ngo
Work in the Ngo Laboratory applies the principles of evolution, chemistry, and engineering to develop new tools for measuring, visualizing, and controlling biomolecules in living cells and organisms. The goal of our work is to develop novel technologies that enable discovery, and to apply those tools to reveal new insights into cellular function and disease. […]
Trevor Siggers
The goal of my laboratory’s research is a systems-level understanding of immune cell responses through integrative proteomic and genomic study of transcription factors (TFs). It is our vision that a biophysical understanding of TF function combined with genome-scale data will lead to quantitative models that can describe immune signaling in healthy and disease states. We have […]
Arturo Vegas
The Vegas group pursues general and systematic approaches to developing targeted therapeutic carriers for the treatment of multiple human diseases. Small-molecule drugs excel at altering disease states at the cellular level, but their therapeutic benefits are often hindered by physiological barriers that impact their toxicity, efficacy, and distribution. The ability to overcome these barriers can […]
Wilson Wong
Our ability to observe biological systems has advanced dramatically over the past decades. However, our ability to modulate and control biology, especially through genetic means, has been lagging. Even with the recent developments in genome editing, we cannot still dynamically regulate cell functions, especially in complex living multicellular organisms such as mammals, with independent control […]
Zeba Wunderlich
Regulatory DNA encodes the gene regulatory networks that are required for virtually every process in an animal, from development to immunity. The Wunderlich lab is interested in understanding how a gene regulatory network’s tasks influence its architecture, robustness, and evolvability. To probe these questions, we use two model systems: the Drosophila early embryonic patterning system […]
Rabia Yazicigil Kirby
My team develops Cyber-Secure Biological Systems uniquely coupling genetically engineered biological systems with secure low-power integrated electronics for healthcare, environmental monitoring, and sustainable manufacturing