{"id":958,"date":"2005-07-01T10:04:00","date_gmt":"2005-07-01T14:04:00","guid":{"rendered":"http:\/\/jaydub.cms-devl.bu.edu\/aodhealth\/2005\/01\/01\/changes-in-alcohol-intake-and-subsequent-health-outcomes\/"},"modified":"2017-01-31T11:47:14","modified_gmt":"2017-01-31T16:47:14","slug":"changes-in-alcohol-intake-and-subsequent-health-outcomes","status":"publish","type":"post","link":"https:\/\/www.bu.edu\/aodhealth\/2005\/07\/01\/changes-in-alcohol-intake-and-subsequent-health-outcomes\/","title":{"rendered":"Changes   in Alcohol Intake and Subsequent Health Outcomes"},"content":{"rendered":"<div class=\"research-summary-body\">\n                    <!-- InstanceBeginEditable name=\"contents\" -->  <\/p>\n<p>To<br \/>\n  assess how changes in drinking over time may impact coronary<br \/>\n  heart disease (CHD), stroke, and all-cause mortality,<br \/>\n  investigators analyzed data from 6544 middle-aged, healthy<br \/>\n  British men who had participated in a 20-year prospective<br \/>\n  study on cardiovascular health. During follow-up, 922<br \/>\n  men died from CHD or had a nonfatal myocardial infarction,<br \/>\n  352 had a stroke, and 1552 died from all causes.\n  <\/p>\n<ul>\n<li>The<br \/>\n  relationship between alcohol intake at study entry and<br \/>\n  the risks of CHD, stroke, and all-cause mortality was<br \/>\n  generally U-shaped, with the lowest risk for subjects<br \/>\n  who consumed 1-2 drinks per day or 1-6 drinks per day<br \/>\n  only on the weekends. <\/li>\n<li>In<br \/>\n  analyses that averaged consumption during follow-up<br \/>\n  (to account for intake over time), the benefits of lighter<br \/>\n  drinking and the risks of heavier drinking increased.<br \/>\n  Further, the risks of nondrinking decreased. <\/li>\n<\/ul>\n<p><!-- InstanceEndEditable --><\/p>\n<div class=\"research-summary-footnotes-1\">\n\t\t\t\t\t\t<!-- InstanceBeginEditable name=\"footnotes-1\" --><!-- InstanceEndEditable -->\n\t\t\t\t\t<\/div>\n<h2 class=\"research-summary-comments\">Comments:<\/h2>\n<p>\t\t\t\t\t<!-- InstanceBeginEditable name=\"comments\" -->  <\/p>\n<p>It<br \/>\n  is laudable to try to account for drinking, and changes<br \/>\n  in drinking, over time when assessing how alcohol use<br \/>\n  influences health outcomes. However, the results of this<br \/>\n  study are difficult to interpret for two major reasons.<br \/>\n  First, by using one value of &#8220;average&#8221; intake, investigators<br \/>\n  cannot accurately assess the effects of changes in drinking<br \/>\n  over time. Second, grouping subjects who drank small amounts<br \/>\n  regularly without bingeing with subjects who were weekend<br \/>\n  bingers is problematic. Researchers should be encouraged<br \/>\n  to study changes in alcohol intake over time, using appropriate<br \/>\n  methods, so we can better understand the effects of alcohol<br \/>\n  on CHD, stroke, and mortality. <\/p>\n<p>  <!-- InstanceEndEditable --><br \/>\n                    <cite><br \/>\n\t\t\t\t\t\t<!-- InstanceBeginEditable name=\"name\" -->  R.<br \/>\n  Curt Ellison, MD<!-- InstanceEndEditable --><br \/>\n\t\t\t\t\t<\/cite><\/p>\n<div class=\"research-summary-footnotes\">\n\t\t\t\t\t<!-- InstanceBeginEditable name=\"footnotes\" --><!-- InstanceEndEditable -->\n\t\t\t\t\t<\/div>\n<h2>Reference:<\/h2>\n<p>\t\t\t\t\t<!-- InstanceBeginEditable name=\"reference\" -->  <\/p>\n<p>Emberson<br \/>\n  JR, Shaper AG, Wannamethee SG, et al. <a href=\"http:\/\/aje.oxfordjournals.org\/cgi\/content\/abstract\/161\/9\/856\" target=\"_blank\">Alcohol intake in<br \/>\n  middle age and risk of cardiovascular disease and mortality:<br \/>\n  accounting for intake variation over time.<\/a> <em>Am J Epidemiol.<br \/>\n  <\/em> 2005;161(9):856-863.<\/p>\n<p>  <!-- InstanceEndEditable -->\n\t\t\t\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>To assess how changes in drinking over time may impact coronary heart disease (CHD), stroke, and all-cause mortality, investigators analyzed data from 6544 middle-aged, healthy British men who had participated in a 20-year prospective study on cardiovascular health. During follow-up, 922 men died from CHD or had a nonfatal myocardial infarction, 352 had a stroke, [&hellip;]<\/p>\n","protected":false},"author":11272,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[16],"tags":[77],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/aodhealth\/wp-json\/wp\/v2\/posts\/958"}],"collection":[{"href":"https:\/\/www.bu.edu\/aodhealth\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bu.edu\/aodhealth\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/aodhealth\/wp-json\/wp\/v2\/users\/11272"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/aodhealth\/wp-json\/wp\/v2\/comments?post=958"}],"version-history":[{"count":1,"href":"https:\/\/www.bu.edu\/aodhealth\/wp-json\/wp\/v2\/posts\/958\/revisions"}],"predecessor-version":[{"id":3094,"href":"https:\/\/www.bu.edu\/aodhealth\/wp-json\/wp\/v2\/posts\/958\/revisions\/3094"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/aodhealth\/wp-json\/wp\/v2\/media?parent=958"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bu.edu\/aodhealth\/wp-json\/wp\/v2\/categories?post=958"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bu.edu\/aodhealth\/wp-json\/wp\/v2\/tags?post=958"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}