{"id":18,"date":"2009-10-23T15:09:36","date_gmt":"2009-10-23T19:09:36","guid":{"rendered":"https:\/\/www.bu.edu\/amyloid\/about\/what\/"},"modified":"2019-08-30T15:58:18","modified_gmt":"2019-08-30T19:58:18","slug":"what","status":"publish","type":"page","link":"https:\/\/www.bu.edu\/amyloid\/what\/","title":{"rendered":"What is Amyloidosis?"},"content":{"rendered":"<p>Amyloidosis is a term for diseases that have in common the extracellular deposition of insoluble fibrillar proteins in tissues and organs. These are part of a growing group of diseases now thought to be caused by misfolding of proteins.\u00a0 The Amyloidosis Center studies the systemic types of amyloidoses defined under amyloid types.\u00a0 Other forms of amyloidosis include Alzheimer\u2019s and other neurodegenerative diseases, prion diseases, serpinopathies, some of the cystic fibrosis, and others. A unifying feature of the amyloidoses is that the deposits share a common \u00df-pleated sheet structural conformation that confers unique staining properties.<\/p>\n<p style=\"text-align: justify;\"><a href=\"\/amyloid\/files\/2009\/10\/Abd-fat23.jpg\"><\/a><a href=\"\/amyloid\/files\/2009\/10\/Abd-fat-10-042.jpg\"><\/a><\/p>\n<div style=\"text-align: left;\" class=\"mceTemp mceIEcenter\">\n<figure id=\"attachment_1095\" aria-describedby=\"caption-attachment-1095\" style=\"width: 519px\" class=\"wp-caption aligncenter\"><a href=\"\/amyloid\/files\/2009\/10\/abdominal-fat1.jpg\"><img loading=\"lazy\" alt=\"Abdominal fat aspirate stained with Congo red and viewed under polarization microscopy showing green birefringence.\" src=\"\/amyloid\/files\/2009\/10\/abdominal-fat1.jpg\" title=\"abdominal fat\" class=\"size-full wp-image-1095 \" height=\"164\" width=\"509\" srcset=\"https:\/\/www.bu.edu\/amyloid\/files\/2009\/10\/abdominal-fat1.jpg 944w, https:\/\/www.bu.edu\/amyloid\/files\/2009\/10\/abdominal-fat1-650x209.jpg 650w\" sizes=\"(max-width: 509px) 100vw, 509px\" \/><\/a><figcaption id=\"caption-attachment-1095\" class=\"wp-caption-text\">Abdominal fat aspirate stained with Congo red and viewed under polarization microscopy showing green birefringence.<\/figcaption><\/figure>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Amyloidosis is a term for diseases that have in common the extracellular deposition of insoluble fibrillar proteins in tissues and organs. These are part of a growing group of diseases now thought to be caused by misfolding of proteins.\u00a0 The Amyloidosis Center studies the systemic types of amyloidoses defined under amyloid types.\u00a0 Other forms of [&hellip;]<\/p>\n","protected":false},"author":1963,"featured_media":0,"parent":0,"menu_order":6,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.bu.edu\/amyloid\/wp-json\/wp\/v2\/pages\/18"}],"collection":[{"href":"https:\/\/www.bu.edu\/amyloid\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bu.edu\/amyloid\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/amyloid\/wp-json\/wp\/v2\/users\/1963"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/amyloid\/wp-json\/wp\/v2\/comments?post=18"}],"version-history":[{"count":24,"href":"https:\/\/www.bu.edu\/amyloid\/wp-json\/wp\/v2\/pages\/18\/revisions"}],"predecessor-version":[{"id":3859,"href":"https:\/\/www.bu.edu\/amyloid\/wp-json\/wp\/v2\/pages\/18\/revisions\/3859"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/amyloid\/wp-json\/wp\/v2\/media?parent=18"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}