Medicine, Immunology, Ophthalmology – Taylor
Medicine, Immunology, Ophthalmology
Options: Volunteer Basis, Potential for Academic Credit
Within the healthy eye, there are specific neuropeptides that control and manipulate immunity necessary to preserve vision. These neuropeptides individually modulate different immune cells and immune cell functions. Collectively they suppress inflammation and make the immune system regulate itself. Understanding how each of these neuropeptides alter immunity and how they work together to suppress inflammation has a profound impact on finding ways to reestablishing a healthy eye with inflammation caused by autoimmune disease, trauma, graft rejection, and aging. In addition, this understanding advances the use of neuropeptides as therapy to regulate immunity. Our experimental approaches use techniques of molecular, biochemical, flow cytometry, gene delivery, cultured immune cells, and autoimmune disease models.